Evaluation of the Protective Efficacy of Different Doses of a Chlamydia abortus Subcellular Vaccine in a Pregnant Sheep Challenge Model for Ovine Enzootic Abortion

Autor: Morag Livingstone, Kevin Aitchison, Javier Palarea-Albaladejo, Francesca Chianini, Mara Silvia Rocchi, Sergio Gastón Caspe, Clare Underwood, Allen Flockhart, Nicholas Wheelhouse, Gary Entrican, Sean Ranjan Wattegedera, David Longbottom

Publikováno v: Animals, Vol 14, Iss 20, p 3004 (2024)

Chlamydia abortus causes the disease ovine enzootic abortion, which is one of the most infectious causes of foetal death in small ruminants worldwide. While the disease can be controlled using live and inactivated commercial vaccines, there is scope

Externí odkaz: https://doaj.org/article/07d8797f458c4142bdb22cae51c6e1bb

Virulence related traits in yeast species associated with food; Debaryomyces hansenii, Kluyveromyces marxianus, and Wickerhamomyces anomalus

Autor: Laura Pérez-Través, Rosa de Llanos, Marizeth Groenewald, Roberto Pérez-Torrado, Lydia García-Domingo, Amparo Querol, Allen Flockhart

Publikováno v: FOOD CONTROL, 124:107901. Elsevier B.V.
Digital.CSIC. Repositorio Institucional del CSIC
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There is an increase in the number of human infections associated with yeast species that are also known to be involved in processing foods such as Saccharomyces cerevisiae, Debaryomyces hansenii, Wickerhamomyces anomalus, or Kluyveromyces marxianus.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d34aba44102a45c249f16f819956374

Identification of a novel prophage regulator in Escherichia coli controlling the expression of type III secretion

Autor: John M. Leong, Allen Flockhart, Christopher Low, Thamarai Schneiders, Ronen Rosenblum, Angus I. Best, Chad R. Laing, Victor P. J. Gannon, David L. Gally, Sean P. McAteer, Maryia Karpiyevich, Roberto M. La Ragione, Kenan C. Murphy, Xuefang Xu, Darren J. Shaw, Jai J. Tree

Publikováno v: Flockhart, A F, Tree, J J, Xu, X, Karpiyevich, M, McAteer, S P, Rosenblum, R, Shaw, D J, Low, C J, Best, A, Gannon, V, Laing, C, Murphy, K C, Leong, J M, Schneiders, T, La Ragione, R & Gally, D L 2012, ' Identification of a novel prophage regulator in Escherichia coli controlling the expression of type III secretion ', Molecular Microbiology, vol. 83, no. 1, pp. 208-223 . https://doi.org/10.1111/j.1365-2958.2011.07927.x
Molecular Microbiology
Flockhart, A F, Tree, J J, Xu, X, Karpiyevich, M, McAteer, S P, Rosenblum, R, Shaw, D J, Low, C J, Best, A, Gannon, V, Laing, C, Murphy, K C, Leong, J M, Schneiders, T, La Ragione, R & Gally, D L 2012, ' Identification of a novel prophage regulator in Escherichia coli controlling the expression of type III secretion. ', Molecular Microbiology, vol. 83, no. 1, pp. 208-223 .

This study has identified horizontally acquired genomic regions of enterohaemorrhagic Escherichia coli O157:H7 that regulate expression of the type III secretion (T3S) system encoded by the locus of enterocyte effacement (LEE). Deletion of O‐island

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34def9761558583ab753579e7499c0a5
https://doi.org/10.1111/j.1365-2958.2011.07927.x

Mucosal antibody responses of colonized cattle toEscherichia coliO157-secreted proteins, flagellin, outer membrane proteins and lipopolysaccharide

Autor: Allen Flockhart, David L. Gally, J. Christopher Low, Nicola Holden, Stuart W. Naylor, Sean P. McAteer, Dai Wang, Pablo Nart, John F. Huntley

Publikováno v: FEMS Immunology & Medical Microbiology. 52:59-68

The aim of this work was to characterize adaptive mucosal immune responses to Escherichia coli O157:H7 at the principal site of colonization in the bovine species. Following experimental infection, extracts from terminal rectum mucosal samples were t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645a9e9083b51070b1e6b8b544c13042
https://doi.org/10.1111/j.1574-695x.2007.00341.x

Transcriptional regulators of the GAD acid stress island are carried by effector protein-encoding prophages and indirectly control type III secretion in enterohemorrhagic Escherichia coli O157:H7

Autor: Jai J, Tree, Andrew J, Roe, Allen, Flockhart, Sean P, McAteer, Xuefang, Xu, Darren, Shaw, Arvind, Mahajan, Scott A, Beatson, Angus, Best, Sabrina, Lotz, Martin J, Woodward, Roberto, La Ragione, Kenan C, Murphy, John M, Leong, David L, Gally

Publikováno v: Molecular microbiology. 80(5)

Type III secretion (T3S) plays a pivotal role in the colonization of ruminant hosts by Enterohemorrhagic Escherichia coli (EHEC). The T3S system translocates effector proteins into host cells to promote bacterial attachment and persistence. The reper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::93fa91289f8ae7eb2bb174c11e1e5d33
https://pubmed.ncbi.nlm.nih.gov/21492263