Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Allen E. Coleman"'
Autor:
Herbert C. Morse, Siegfried Janz, Sung Sup Park, Jerrold M. Ward, Tadamitsu Kishimoto, Allen E. Coleman, Michael Potter, Alexander L. Kovalchuk, Joong Su Kim
Publikováno v:
Proceedings of the National Academy of Sciences. 99:1509-1514
Plasma cell neoplasms in humans comprise plasma cell myeloma, otherwise known as multiple myeloma, Ig deposition and heavy chain diseases, and plasmacytoma (PCT). A subset of PCT, designated extramedullary PCT, is distinguished from multiple myeloma
Autor:
Thomas Ried, Christoph Cremer, Sung S. Park, Alexander L. Kovalchuk, Allen E. Coleman, Arif Esa, Siegfried Janz
Publikováno v:
Genes, Chromosomes and Cancer. 30:283-291
Myc-activating chromosomal 12;15 translocations, the hallmark mutations of inflammation-induced BALB/c plasmacytomas, have recently been shown to undergo remodeling by isotype switch-like genetic recombinations that remove approximately 180 kb of imm
Autor:
Allen E. Coleman, Stacie M. Anderson, Marek Liyanage, Thomas Ried, Daniel G. Pankratz, Carrolee Barlow, Zoë Weaver, Anthony Wynshaw-Boris
Publikováno v:
Blood. 96:1940-1946
Atm-deficient mice (Atm−/−) recapitulate many aspects of the ataxia telangiectasia (AT) syndrome, including the susceptibility to tumors of lymphoid origin. To investigate the mechanism of tumorigenesis, we have examined a panel of 8 thymic lymph
Autor:
Herbert C. Morse, B. Hilda Ye, Mitsuo Hori, Sisir K. Chattopadhyay, Chen Feng Qi, Janet W. Hartley, Allen E. Coleman, Ted A. Torrey, Lekidelu Taddesse-Heath
Publikováno v:
Leukemia Research. 24:719-732
BCL6 encodes a transcription factor deregulated by chromosomal translocations in human diffuse large cell B lymphomas (DLCL). This study was designed to determine whether Bcl6 might also be involved in lymphomas of mice. BCL6 protein was expressed at
Autor:
Ulli Weier, Michael P. Diamond, Alexandre N. Ermilov, Thomas M. Reid, Allen E. Coleman, Peter Nagy, D. Dozortsev, Marek Liyanage
Publikováno v:
Fertility and Sterility. 73:366-371
Objective: To investigate the arrangement of chromosomes within pronuclei-stage mouse zygotes. Design: In vitro study. Setting: Academic medical center. Patient(s): None. Intervention(s): None. Main Outcome Measure(s): Location of major α-satellite
Autor:
Jan Ellenberg, Andrea Farina, Anup Dey, Keiko Ozato, Selvaggia Sciortino, Allen E. Coleman, Jennifer Lippincott-Schwartz, Tetsuo Maruyama
Publikováno v:
Molecular and Cellular Biology. 20:6537-6549
We describe a novel nuclear factor called mitotic chromosome-associated protein (MCAP), which belongs to the poorly understood BET subgroup of the bromodomain superfamily. Expression of the 200-kDa MCAP was linked to cell division, as it was induced
Autor:
Zoë Weaver, Thomas Ried, RuiBai Luo, Hannah M. Young, Zhao-Qi Wang, Allen E. Coleman, Cynthia M. Simbulan-Rosenthal, Bassem R. Haddad, Mark E. Smulson, Dean S. Rosenthal
Publikováno v:
Proceedings of the National Academy of Sciences. 96:13191-13196
Depletion of poly(ADP-ribose) polymerase (PARP) increases the frequency of recombination, gene amplification, sister chromatid exchanges, and micronuclei formation in cells exposed to genotoxic agents, implicating PARP in the maintenance of genomic s
Autor:
Alexander L. Kovalchuk, Allen E. Coleman, Thomas Ried, Nicole McNeil, ST Forest, Siegfried Janz
Publikováno v:
Leukemia. 13:1592-1600
Spectral karyotyping (SKY) and comparative genomic hybridization (CGH) were used to elucidate the divergent cytogenetic make-up of the prototypical bilineage lymphoblastic pre-B lymphoma, P388, and its progenitor macrophage-like tumor, P388D1. P388 w
Autor:
Stan du Manoir, Allen E. Coleman, Evelin Schröck, Stephen J McCormack, Zoë Weaver, Robert B. Dickson, Marek Liyanage, Thomas Ried
Publikováno v:
Genes, Chromosomes and Cancer. 25:251-260
Mice carrying the MMTV-cmyc transgene develop mammary tumors at 9 to 12 months of age. Little is known about karyotypic changes in this model of human breast cancer. We have developed and applied molecular cytogenetic techniques to study chromosomal
Autor:
Gary M. Jones, D. Siwarski, Guillaume Dighiero, Allen E. Coleman, Jennifer Kim, Lena Diaw, Konrad Huppi
Publikováno v:
The Journal of Experimental Medicine
The many binding studies of monoclonal immunoglobulin (Ig) produced by plasmacytomas have found no universally common binding properties, but instead, groups of plasmacytomas with specific antigen-binding activities to haptens such as phosphorylcholi