Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Allen E. Cato"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:1788-1793
The effect of coadministration of ritonavir and zidovudine (ZDV) on the pharmacokinetics of these drugs was investigated in a three-period, multidose, crossover study. Eighteen asymptomatic, human immunodeficiency virus-positive men were assigned ran
Publikováno v:
Clinical Pharmacology & Therapeutics. 63:414-421
Objective To investigate the effects of ritonavir on the pharmacokinetics of rifabutin. Methods In a multiple-dose, randomized, parallel-group, double-blind study, subjects received 150 mg rifabutin daily for 24 days coadministered on days 15 to 24 w
Publikováno v:
Journal of pharmaceutical sciences. 85(4)
The effect of age on the in vitro binding of valproic acid (VPA) to serum proteins was investigated in rats ranging in age from 14 days (preweaning) to 24 months (senescent). The influence of free fatty acid (FFA) and total protein (TP) concentration
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 25(3)
1. Age-dependent differences in the intestinal hydrolysis of the glucuronide conjugate of valproic acid were evaluated in the Fisher-344 rat at 14 and 40 days, and 24 months of age. 2. Hydrolysis occurred more quickly when incubations were conducted
Publikováno v:
Seminars in Thrombosis and Hemostasis. 7:43-51
Publikováno v:
Clinical pharmacology and therapeutics. 30(2)
The effects of sequential prostacyclin infusions at 2, 4, and 8 ng/kg/min for 1 hr were determined in six patients with chronic renal failure. Diastolic blood pressure decreased in a dose-dependent fashion from 74 +/- 4 mm Hg (mean +/- SEM) to 70 +/-
Publikováno v:
Drug intelligenceclinical pharmacy. 21(1 Pt 2)
The UNC/BW fellowship, like other industry/academia collaborative fellowships, provides a unique training experience in clinical research. Both academia and the pharmaceutical industry have opened their doors and allowed clinical pharmacists to spend
Publikováno v:
Drug intelligenceclinical pharmacy. 15(11)
Over the past six years, both governmental institutions and private enterprise have expressed great interest and activity in the isolation of chemical constituents from the Cannabis sativa plant and synthesis of novel cannabinoid compounds with poten
Autor:
David M. Cocchetto, Nina Tolkoff-Rubin, Robert H. Rubin, James W. Crow, Allen E. Cato, Randall M. Zusman
Publikováno v:
The New England journal of medicine. 304(16)
Anticoagulation during hemodialysis is necessary to prevent clotting of the blood on contact with the dialysis membrane. Heparin is the usual anticoagulant used, but systemic anticoagulation may persist for hours, and hemorrhage is common. We success