Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Allen E. Buhl"'
Autor:
Gabriel Vogeli, Daniel J. Waldon, Vince Groppi, Thomas T. Kawabe, Linda S. Wood, Paul S. Kaytes, Thomas E. Wagner, Thomas J. Rea, Allen E. Buhl, Alistair R. McNab
Publikováno v:
Annals of the New York Academy of Sciences. 642:21-30
We analyzed the effect of minoxidil on hair follicles isolated from transgenic mice. These transgenic animals synthesize the reporter enzyme CAT in their hair follicles only during the active phases of hair growth. The recombinant gene used to genera
Autor:
Thomas T. Kawabe, Karl Kappenman, Roger A. Poorman, Barry S. Lutzke, Dennis E. Epps, Antonio Molinari, Ronald W. Sarver, Allen E. Buhl, Bruce M. Taylor, Gregory J. Fici
Publikováno v:
Journal of Protein Chemistry. 22:31-40
The time dependency of the spontaneous aggregation of the fibrillogenic beta-amyloid peptide, Abeta1-40, was measured by turbidity, circular dichroism, HPLC, and fluorescence polarization. The results by all methods were comparable and they were most
Autor:
Jinhe Li, Mark E. Gurney, Allen E. Buhl, Rongqing Shuang, Richard L. Myers, Cara L. Ruble, Riqiang Yan, John R. Brashler, Adele M. Pauley
Publikováno v:
Journal of Neurochemistry. 82:1540-1548
Mutations in the human presenilin genes (PS1 or PS2) have been linked to autosomal dominant, early onset Alzheimer's disease (AD). Presenilins, probably as an essential part of gamma-secretase, modulate gamma-cleavage of the amyloid protein precursor
Autor:
Mary E. Shuck, Donald B. Carter, John R. Brashler, Mark E. Gurney, Alfredo G. Tomasselli, Luis A. Parodi, Riqiang Yan, Michael Jerome Bienkowski, Monica C. Tory, Allen E. Buhl, Nancy C. Stratman, Adele M. Pauley, Robert L. Heinrikson, W. Rodney Mathews, Huiyi Miao
Publikováno v:
Nature. 402:533-537
Mutations in the gene encoding the amyloid protein precursor (APP) cause autosomal dominant Alzheimer's disease. Cleavage of APP by unidentified proteases, referred to as beta- and gamma-secretases, generates the amyloid beta-peptide, the main compon
Autor:
Kerry L. Blacker, H.G. Kampffmeyer, Allen E. Buhl, A. R. Diani, B. Henrikus, Christian Weiss, Thomas D. Boyer, B. Gabard, Anthony W. Ford-Hutchinson, Ulrich Täuber, Cynthia J. Mills, Louis Dubertret, A. Li Wan Po, P. Treffel, M. Charveron, S.Y. Chan, A. Moysan, Donald A. Vessey, D. Averbeck, Roger G. Ulrich, Kyung-Hee Lee, H. Matthes, A. Er-raki, J.L. Bonafé, Patrice Morlière
Publikováno v:
Skin Pharmacology and Physiology. 6:I-IV
Publikováno v:
Skin Pharmacology and Physiology. 6:259-267
The purpose of these experiments was to determine if an extracellular calcium binding site gradient is evident in freshly dissected or cultured mouse vibrissa and human scalp follicles and to measure possible drug effects on this gradient. Mouse vibr
Autor:
Kevin J Stefanski, Allen E. Buhl, Heinrich J. Schostarez, Bharat V. Kamdar, Marshall N. Brunden, Lisa Marie Thomasco, Garland A. Johnson, Kathy L. Shull, Daniel J. Waldon, Randall G. Stehle, A. R. Diani, Michael J. Mulholland, Theresa M. Schwartz, Steven J. Conrad, Robert C. Gadwood, Marc F. Kubicek
Publikováno v:
Journal of Investigative Dermatology. 98:315-319
The opening of intracellular potassium channels has been suggested as a mechanism regulating hair growth. Enhancing the flux of potassium ions is a mechanism shared by several structurally diverse antihypertensive agents including minoxidil sulfate (
Autor:
Donald K. MacCallum, Daniel J. Waldon, Garland A. Johnson, Karen A. Knight, Thomas T. Kawabe, Allen E. Buhl
Publikováno v:
Skin Pharmacology and Physiology. 5:114-123
To identify minoxidil target cells in hair follicles we followed the uptake of radiolabeled drug in mouse vibrissae follicles both in vitro and in vivo. Autoradiography showed that both 3H-minoxidil and 3H-minoxidil sulfate accumulated in the differe
Autor:
Thomas J. Rea, Paul S. Kaytes, Gabriel Vogeli, Arthur P. Bertolino, Allen E. Buhl, Alistair R. McNab, Nicole T. Hatzenbuhler, Thomas T. Kawabe, Vince Groppi
Publikováno v:
Journal of Investigative Dermatology. 97:835-842
A genomic clone for a member of the mouse type I hair keratin protein family has been isolated and analyzed in order to study the regulation of this keratin during the hair growth cycle. The coding sequence is divided into seven exons. The gene struc
Autor:
Vince Groppi, Gabriel Vogeli, Daniel J. Waldon, Thomas J. Rea, Paula Andrus, Thomas E. Wagner, Allen E. Buhl, Alistair R. McNab, Thomas K. Kawabe
Publikováno v:
Proceedings of the National Academy of Sciences. 87:6848-6852
We have generated a transgenic mouse line by microinjection of a chimeric DNA fragment (KER-CAT) containing a hair-specific, murine ultra-high-sulfur keratin promoter (KER) fused to the coding region of the bacterial chloramphenicol acetyltransferase