Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Allen C. T. Teng"'
Autor:
Allen C. T. Teng, Liyang Gu, Michelle Di Paola, Robert Lakin, Zachary J. Williams, Aaron Au, Wenliang Chen, Neal I. Callaghan, Farigol Hakem Zadeh, Yu-Qing Zhou, Meena Fatah, Diptendu Chatterjee, L. Jane Jourdan, Jack Liu, Craig A. Simmons, Thomas Kislinger, Christopher M. Yip, Peter H. Backx, Robert G. Gourdie, Robert M. Hamilton, Anthony O. Gramolini
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The intercalated disc (ICD) is a membrane structure of the cardiac muscle involved in normal heart function. Here the authors report that knockdown of the ICD-bound transmembrane protein 65 results in impaired ICD structure, abnormal cardiac electrop
Externí odkaz:
https://doaj.org/article/aafde2c6ca28412ea8f19a14b47c1f34
Autor:
Shin-Haw Lee, Sina Hadipour-Lakmehsari, Harsha R. Murthy, Natalie Gibb, Tetsuaki Miyake, Allen C. T. Teng, Jake Cosme, Jessica C. Yu, Mark Moon, SangHyun Lim, Victoria Wong, Peter Liu, Filio Billia, Rodrigo Fernandez-Gonzalez, Igor Stagljar, Parveen Sharma, Thomas Kislinger, Ian C. Scott, Anthony O. Gramolini
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
The sarcoplasmic (SR) and endoplasmic reticulum (ER) are involved in heart development but how this arises is unclear. Here, the authors show that loss of a SR/ER protein REEP5 causes membrane destabilization and decreased cardiac myocyte contractili
Externí odkaz:
https://doaj.org/article/9f62361bf8a34f7da79df62e9762126b
Autor:
Farigol Hakem Zadeh, Allen C. T. Teng, Uros Kuzmanov, Paige J. Chambers, Allan R. Tupling, Anthony O. Gramolini
Publikováno v:
Physiological Reports, Vol 7, Iss 14, Pp n/a-n/a (2019)
Abstract Phospholamban (PLN) is an important Ca2+ modulator at the sarcoplasmic reticulum (SR) of striated muscles. It physically interacts and inhibits sarcoplasmic reticulum Ca2+ ATPase (SERCA2) function, whereas a protein kinase A (PKA)‐dependen
Externí odkaz:
https://doaj.org/article/fddcae4ea88746798cb6cd54d91145c2
Autor:
Sean R. Cleary, Allen C. T. Teng, Audrey Deyawe Kongmeneck, Xuan Fang, Taylor A. Phillips, Ellen E. Cho, Peter Kekenes-Huskey, Anthony O. Gramolini, Seth L. Robia
Publikováno v:
bioRxiv
The sarco(endo)plasmic reticulum Ca2+ATPase (SERCA) is a membrane transporter that creates and maintains intracellular Ca2+stores. In the heart, SERCA is regulated by an inhibitory interaction with the monomeric form of the transmembrane micropeptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c50f8b7d085d24bd7bbfc13b3549c6
https://doi.org/10.1101/2023.05.26.542463
https://doi.org/10.1101/2023.05.26.542463
Autor:
Cristine J. Reitz, Marjan Tavassoli, Da Hye Kim, Saumya Shah, Robert Lakin, Allen C. T. Teng, Yu-Qing Zhou, Wenping Li, Sina Hadipour-Lakmehsari, Peter H. Backx, Andrew Emili, Gavin Y. Oudit, Uros Kuzmanov, Anthony O. Gramolini
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The prognosis and treatment outcomes of heart failure (HF) patients rely heavily on disease etiology, yet the majority of underlying signaling mechanisms are complex and not fully elucidated. Phosphorylation is a major point of protein regulation wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d06b71f0cbf827b0d57975817e32af14
https://doi.org/10.1073/pnas.2212118120
https://doi.org/10.1073/pnas.2212118120
Autor:
Suja Shrestha, Meghan J. McFadden, Allen C. T. Teng, Patrick Dong Min Chang, Joyce Deng, Tatianna W. Y. Wong, Ronald D. Cohn, Evgueni A. Ivakine, Anthony O. Gramolini, J. Paul Santerre
Publikováno v:
ACS Applied Materials & Interfaces. 13:58352-58368
Developing safe and effective strategies to deliver biomolecules such as oligonucleotides and proteins into cells has grown in importance over recent years, with an increasing demand for non-viral methods that enable clinical translation. Here, we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263f013586bb0dd551cd3774b30b5414
https://doi.org/10.1021/acsami.1c17868
https://doi.org/10.1021/acsami.1c17868
Autor:
Tetsuaki Miyake, Filio Billia, Thomas Kislinger, Peter Liu, Natalie Gibb, Mark Moon, Parveen Sharma, Shin-Haw Lee, Igor Stagljar, Allen C. T. Teng, Jake Cosme, Ian C. Scott, Anthony O. Gramolini, Victoria Wong, Jessica C. Yu, Sanghyun Lim, Sina Hadipour-Lakmehsari, Harsha R. Murthy, Rodrigo Fernandez-Gonzalez
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Cell Stress
NATURE COMMUNICATIONS
Cell Stress
NATURE COMMUNICATIONS
The sarco-endoplasmic reticulum (SR/ER) is the largest membrane-bound organelle in eukaryotic cells and plays important roles in essential cellular processes, and in development and progression of many cardiac diseases. However, many aspects of its s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807832a1ccff6438b218fdb0173bb7ad
https://doaj.org/article/9f62361bf8a34f7da79df62e9762126b
https://doaj.org/article/9f62361bf8a34f7da79df62e9762126b
Autor:
Anthony O. Gramolini, Jessica L. Braun, Rebecca E. K. MacPherson, Val A. Fajardo, Rachel K. Fenech, Chantal R. Ryan, Allen C. T. Teng, Mia S. Geromella
Publikováno v:
FEBS lettersReferences. 595(22)
Neuronatin (NNAT) is a transmembrane protein in the endoplasmic reticulum involved in metabolic regulation. It shares sequence homology with sarcolipin (SLN), which negatively regulates the sarco(endo)plasmic reticulum Ca2+ -ATPase (SERCA) that maint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d679cf36470e3cbdec8277baff54425
https://pubmed.ncbi.nlm.nih.gov/34693525
https://pubmed.ncbi.nlm.nih.gov/34693525
Autor:
Zachary J. Williams, Diptendu Chatterjee, J. J Jourdan, Michelle Di Paola, Yu-Qing Zhao, Allen C. T. Teng, Liyang Gu, Anthony O. Gramolini, Neal I. Callaghan, Craig A. Simmons, Christopher M. Yip, Robert G. Gourdie, Thomas Kislinger, Farigol Hakem Zadeh, Robert M. Hamilton, Aaron Au, Meena Fatah
Publikováno v:
Circulation Research. 129
The intercalated disc (ICD) is unique membrane structure that is indispensable to normal heart function. However, its structural organization is not well understood. Previously, we showed that the ICD-bound transmembrane protein 65 (Tmem65) was requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7ea46552c809745e319ec872eceb599
https://doi.org/10.1161/res.129.suppl_1.p361
https://doi.org/10.1161/res.129.suppl_1.p361
Autor:
Shin-Haw Lee, Cristine J Reitz, Sina Hadipour-Lakmehsari, Anthony O. Gramolini, Da Hye Kim, Uros Kuzmanov, Allen C. T. Teng, Andrew Emili, Marjan Tavassoli, Saumya Shah, Gavin Y. Oudit
Publikováno v:
Circulation Research. 129
Dilated cardiomyopathy (DCM) is one of the most common causes of heart failure, yet the majority of the underlying signaling mechanisms remain poorly characterized. Protein phosphorylation is a key regulatory element with profound effects on the acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0560aa357cdb8a5c7a39f825392db5d
https://doi.org/10.1161/res.129.suppl_1.mp216
https://doi.org/10.1161/res.129.suppl_1.mp216