Zobrazeno 1 - 10
of 458
pro vyhledávání: '"Allele-specific oligonucleotide"'
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Here we compared clonotype identification by allele-specific oligonucleotide real-time quantitative-PCR (ASO RQ-PCR) and next-generation sequencing (NGS) in 80 multiple myeloma patients. ASO RQ-PCR was applicable in 49/55 (89%) and NGS in 62/78 (80%)
Externí odkaz:
https://doaj.org/article/d7e1321a42ff4a0c868eb821a207ba0d
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Next-generation sequencing (NGS) has been applied to monitor minimal residual disease (MRD) in multiple myeloma (MM). Standardized DNA input and sequencing depth is essential for achieving a uniform sensitivity in NGS-based MRD study. Herein, the sen
Externí odkaz:
https://doaj.org/article/95a5e973153148678046ecda34f8b8d5
Autor:
Rashid Mir, Mirza Masroor, Jamsheed Javid, Imtiyaz Ahamad, Shazia Farooq, Prasant Yadav, Mariyam Zuberi, Maqbool Lone, P C Ray, Alpana Saxena
Publikováno v:
South Asian Journal of Cancer, Vol 5, Iss 1, Pp 33-36 (2016)
Aim: Lung cancer is considered to be the most common cancer in the world. In humans, about 50% or more cancers have a mutated tumor suppressor p53 gene thereby resulting in accumulation of p53 protein and losing its function to activate the target ge
Externí odkaz:
https://doaj.org/article/038fa4cb54dd4c6ea73ba60a1c728558
Autor:
Israa Saeed Abbas
Publikováno v:
Journal of Contemporary Medical Sciences, Vol 2, Iss 8, Pp 138-140 (2016)
Objectives This study includes the investigation of antifungal activity of the local propolis against dermatophytes and yeast. Methods A total of 92 tissue samples were taken from patients infected with H. pylori and 102 from uninfected individuals h
Externí odkaz:
https://doaj.org/article/e1df3504882344a29b7f5161c16994fe
Autor:
Ezzat Allah Ghaemi, Somayeh Rahimi, Hesamaddin Shirzad-Aski, Basireh Baei, Masoume Taziki, Maya Babaii Kochaksaraei, Ahmad Sohrabi, Maryam Shafipour, Kiarash Ghazvini
Publikováno v:
Current Microbiology. 78:4009-4013
Mycobacterium tuberculosis (M. tuberculosis) genotyping provides valuable information related to the origin and the evolution of the isolates. This study aimed to evaluate the applicability of single-nucleotide polymorphisms (SNPs) technique for line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2395398b8117e67d15c82e1a83d51e93
https://doi.org/10.1007/s00284-021-02659-7
https://doi.org/10.1007/s00284-021-02659-7
Publikováno v:
International Journal of Legal Medicine. 136:93-101
Genotype profiling has played a major role in forensics for decades. The technology for detection and discrimination has advanced substantially, from serology to DNA sequence analysis. Currently, there may be situations where there is a need for re-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16472546670ff0d22a7e63b0247d603e
https://doi.org/10.1007/s00414-021-02647-3
https://doi.org/10.1007/s00414-021-02647-3
Publikováno v:
Expert Opinion on Investigational Drugs. 29:1125-1132
Huntington's disease (HD) is an incurable, autosomal dominant neurodegenerative disease caused by an abnormally long polyglutamine tract in the huntingtin protein. Because this mutation causes disease via gain-of-function, lowering huntingtin levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1627b4b8c911f22a8f16fdfbbe75af50
https://doi.org/10.1080/13543784.2020.1804552
https://doi.org/10.1080/13543784.2020.1804552
Autor:
Jamshaid A. Siddiqui, Naseem Akhter, Nootan Kumar Shukla, Syed Akhtar Husain, Farah Parveen, Mohammad Margoob Ahmad
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: Cytokines are the key regulator molecules that modulate immune response. Tumor necrosis factor (TNF- α-308 G/A and TNF-β +252 A/G ) are inflammatory cytokine that control the progression of several types of cancer. They play a vital rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76db58eec0c44155cd66ac31a9b08f1e
https://doi.org/10.31557/apjcp.2020.21.2.301
https://doi.org/10.31557/apjcp.2020.21.2.301
Autor:
Jogeshwar Binota, Neelam Varma, Purnima Malhotra, Subhash Varma, Shano Naseem, Karthik Bommannan
Publikováno v:
Journal of postgraduate medicine. 68(2)
Introduction Despite the impressive responses achieved with tyrosine kinase inhibitor (TKI) therapy, treatment resistance develops in 16-33% of patients of chronic myelogenous leukemia (CML). Of the BCR-ABL1 dependent mechanisms, mutations in the tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621345876157d634149a21e45fb7e2d3
https://pubmed.ncbi.nlm.nih.gov/34747876
https://pubmed.ncbi.nlm.nih.gov/34747876
Autor:
Tipaya Ekalaksananan, Jureeporn Chuerduangphui, Natcha Patarapadungkit, Chamsai Pientong, Supannee Promthet, Patravoot Vatanasapt, Weerayut Wongjampa, Pensiri Phusingha
Publikováno v:
Pathology & Oncology Research. 26:1191-1199
Alterations of the P53 gene and human papillomavirus (HPV) infection are associated with development of oral squamous cell carcinoma (OSCC). We aimed to identify mutation of P53 exon 8 codon 282 in OSCC and correlate these with HPV infection as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3794a3a9c310808ca6b0c499d8f15332
https://doi.org/10.1007/s12253-019-00673-6
https://doi.org/10.1007/s12253-019-00673-6