Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Allein Plain"'
Autor:
Allein Plain, Wanling Pan, Deborah O’Neill, Megan Ure, Megan R. Beggs, Maikel Farhan, Henrik Dimke, Emmanuelle Cordat, R. Todd Alexander
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2074 (2020)
The renal proximal tubule (PT) is responsible for the reabsorption of approximately 65% of filtered calcium, primarily via a paracellular pathway. However, which protein(s) contribute this paracellular calcium pore is not known. The claudin family of
Externí odkaz:
https://doaj.org/article/d6cfbb692c604a0dbde7c9116243e510
Publikováno v:
F1000Research, Vol 6 (2017)
Calcium and phosphate are critical for a myriad of physiological and cellular processes within the organism. Consequently, plasma levels of calcium and phosphate are tightly regulated. This occurs through the combined effects of the phospho- and calc
Externí odkaz:
https://doaj.org/article/1f1ffd1c3d4e442e8940bc635c868702
Autor:
Carlos Manlio Díaz García, Frank Coro Antich, Allein Plain Reyes, Andrés Machado García, Evelyn Rodríguez
Publikováno v:
Revista Cubana de Investigaciones Biomédicas, Vol 27, Iss 1, p 0 (2008)
Introducción: La Variabilidad de la Frecuencia Cardíaca (VFC) constituye un instrumento de cuantificación de la actividad autónoma ante diferentes situaciones patofisiológicas. Objetivos: Caracterizar el efecto de la edad sobre el control autón
Externí odkaz:
https://doaj.org/article/a4522a0d3cdf49ca9af491c538effaed
Autor:
Wanling Pan, Debbie O'Neill, Kennedi Young, Allein Plain, Juraj Rievaj, Matthew Saurette, R. Todd Alexander, Emmanuelle Cordat, Megan R Beggs, Michael R. Doschak, Henrik Dimke
Publikováno v:
Beggs, M R, Young, K, Pan, W, O'Neill, D D, Saurette, M, Plain, A, Rievaj, J, Doschak, M R, Cordat, E, Dimke, H & Alexander, R T 2021, ' Claudin-2 and claudin-12 form independent, complementary pores required to maintain calcium homeostasis ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 48, e2111247118 . https://doi.org/10.1073/pnas.2111247118
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Significant calcium absorption across renal and intestinal epithelia occurs via the paracellular pathway. However, the identity of the paracellular pore involved is unknown. Claudin-2 and claudin-12 contribute paracellular calcium permea
Publikováno v:
American Journal of Physiology-Renal Physiology. 317:F240-F253
To garner insights into the renal regulation of Ca2+homeostasis, we performed an mRNA microarray on kidneys from mice treated with the Ca2+-sensing receptor (CaSR) agonist cinacalcet. This revealed decreased gene expression of Na+/H+exchanger isoform
Autor:
Maikel Farhan, Allein Plain, Deborah O'Neill, Emmanuelle Cordat, Megan E Ure, Wanling Pan, Henrik Dimke, R. Todd Alexander, Megan R Beggs
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 6
Plain, A, Pan, W, O'Neill, D, Ure, M, Beggs, M R, Farhan, M, Dimke, H, Cordat, E & Alexander, R T 2020, ' Claudin-12 Knockout Mice Demonstrate Reduced Proximal Tubule Calcium Permeability ', International Journal of Molecular Sciences, vol. 21, no. 6, 2074 . https://doi.org/10.3390/ijms21062074
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2074 (2020)
Volume 21
Issue 6
Plain, A, Pan, W, O'Neill, D, Ure, M, Beggs, M R, Farhan, M, Dimke, H, Cordat, E & Alexander, R T 2020, ' Claudin-12 Knockout Mice Demonstrate Reduced Proximal Tubule Calcium Permeability ', International Journal of Molecular Sciences, vol. 21, no. 6, 2074 . https://doi.org/10.3390/ijms21062074
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2074 (2020)
The renal proximal tubule (PT) is responsible for the reabsorption of approximately 65% of filtered calcium, primarily via a paracellular pathway. However, which protein(s) contribute this paracellular calcium pore is not known. The claudin family of
Autor:
Dominik N. Müller, Allein Plain, Thomas E. Willnow, Markus Bleich, Nina Himmerkus, Dorothee Günzel, Kerim Mutig, Tilman Breiderhoff, Hoora Drewell
Publikováno v:
Kidney International. 93:580-588
The tight junction proteins claudin-10 and -16 are crucial for the paracellular reabsorption of cations along the thick ascending limb of Henle's loop in the kidney. In patients, mutations in CLDN16 cause familial hypomagnesemia with hypercalciuria a
Autor:
Allein Plain, Nina Himmerkus, Markus Bleich, Svenja R. Sonntag, Alexander Paliege, Rita D. Marques, Jens Leipziger
Publikováno v:
Himmerkus, N, Plain, A, Marques, R D, Sonntag, S R, Paliege, A, Leipziger, J & Bleich, M 2017, ' AVP dynamically increases paracellular Na+ permeability and transcellular NaCl transport in the medullary thick ascending limb of Henle's loop ', Pflügers Archiv-European Journal of Physiology, vol. 469, no. 1, pp. 149-158 . https://doi.org/10.1007/s00424-016-1915-5
The medullary thick ascending limb of Henle's loop (mTAL) is crucial for urine-concentrating ability of the kidney. It is water tight and able to dilute the luminal fluid by active transcellular NaCl transport, fueling the counter current mechanism b
Autor:
Shane A, Wiebe, Allein, Plain, Wanling, Pan, Debbie, O'Neill, Branko, Braam, R Todd, Alexander
Publikováno v:
American journal of physiology. Renal physiology. 317(2)
To garner insights into the renal regulation of Ca
Autor:
Nina Himmerkus, Sebastian Bachmann, David H. Ellison, Vera Jankowski, Thomas E. Willnow, Markus Bleich, Rebecca A. Lazelle, Allein Plain, Kerim Mutig, James A. McCormick, Katharina I. Blankenstein, Christin Boldt, Aljona Borschewski
Publikováno v:
Journal of the American Society of Nephrology. 27:107-119
The furosemide-sensitive Na+-K+-2Cl(-)-cotransporter (NKCC2) is crucial for NaCl reabsorption in kidney thick ascending limb (TAL) and drives the urine concentrating mechanism. NKCC2 activity is modulated by N-terminal phosphorylation and dephosphory