Challenges and opportunities for digital twins in precision medicine: a complex systems perspective

Autor: De Domenico, Manlio, Allegri, Luca, Caldarelli, Guido, d'Andrea, Valeria, Di Camillo, Barbara, Rocha, Luis M., Rozum, Jordan, Sbarbati, Riccardo, Zambelli, Francesco

The adoption of digital twins (DTs) in precision medicine is increasingly viable, propelled by extensive data collection and advancements in artificial intelligence (AI), alongside traditional biomedical methodologies. However, the reliance on black-

Externí odkaz: http://arxiv.org/abs/2405.09649

A multi-dimensional Sustainable Diet Index (SDI) for Ghanaian adults under transition: the RODAM Study

Autor: Akinkunmi Paul Okekunle, Mary Nicolaou, Manuela De Allegri, Karlijn A.C. Meeks, Hibbah Osei-Kwasi, Julia Stockemer, Ama de-Graft Aikins, Isaac Agbemafle, Silver Bahendeka, Daniel Boateng, Kerstin Klipstein-Grobusch, Erik Beune, Charles Agyemang, Matthias B. Schulze, Ina Danquah

Publikováno v: Nutrition Journal, Vol 23, Iss 1, Pp 1-12 (2024)

Abstract Background The sustainability of diets consumed by African populations under socio-economic transition remains to be determined. This study developed and characterized a multi-dimensional Sustainable Diet Index (SDI) reflecting healthfulness

Externí odkaz: https://doaj.org/article/2162be3e58bf4f748a604ef45c9d3820

Impact on the nervous system of long COVID-19 infection in children

Autor: Nora Granana, Adriana Tarulla, Ismael Calandri, Analia De Carli, Belen Rivas, Jose Maria Festa, Susana Vacirca, María Lis, Iris Worff, Ricardo Allegri

Publikováno v: Arquivos de Neuro-Psiquiatria, Vol 82, Iss 09, Pp 001-007 (2024)

Background The coronavirus disease 2019 (COVID-19) pandemic has had a profound global impact, raising concerns about its long-term effects, particularly neurological complications. While studies have highlighted such complications in adults, there is

Externí odkaz: https://doaj.org/article/8c07005e3e3e475ba70c05fe4f9f96c0

CSF proteomics identifies early changes in autosomal dominant Alzheimer’s disease

Autor: Noble, James M., Day, Gregory S., Graff-Radford, Neill R., Voglein, Jonathan, Allegri, Ricardo, Mendez, Patricio Chrem, Surace, Ezequiel, Berman, Sarah B., Ikonomovic, Snezana, Nadkarni, Neelesh, Lopera, Francisco, Ramirez, Laura, Aguillon, David, Leon, Yudy, Ramos, Claudia, Alzate, Diana, Baena, Ana, Londono, Natalia, Mathias Jucker, Sonia Moreno, Laske, Christoph, Kuder-Buletta, Elke, Graber-Sultan, Susanne, Preische, Oliver, Hofmann, Anna, Ikeuchi, Takeshi, Kasuga, Kensaku, Niimi, Yoshiki, Ishii, Kenji, Senda, Michio, Sanchez-Valle, Raquel, Rosa-Neto, Pedro, Fox, Nick, Cash, Dave, Lee, Jae-Hong, Roh, Jee Hoon, Riddle, Meghan, Menard, William, Bodge, Courtney, Surti, Mustafa, Takada, Leonel Tadao, Farlow, Martin, Chhatwal, Jasmeer P., Sanchez-Gonzalez, V.J., Orozco-Barajas, Maribel, Goate, Alison, Renton, Alan, Esposito, Bianca, Karch, Celeste M., Marsh, Jacob, Cruchaga, Carlos, Fernandez, Victoria, Gordon, Brian A., Fagan, Anne M., Jerome, Gina, Herries, Elizabeth, Llibre-Guerra, Jorge, Levey, Allan I., Johnson, Erik C.B., Seyfried, Nicholas T., Schofield, Peter R., Brooks, William, Bechara, Jacob, Bateman, Randall J., McDade, Eric, Hassenstab, Jason, Perrin, Richard J., Franklin, Erin, Benzinger, Tammie L.S., Chen, Allison, Chen, Charles, Flores, Shaney, Friedrichsen, Nelly, Hantler, Nancy, Hornbeck, Russ, Jarman, Steve, Keefe, Sarah, Koudelis, Deborah, Massoumzadeh, Parinaz, McCullough, Austin, McKay, Nicole, Nicklaus, Joyce, Pulizos, Christine, Wang, Qing, Mishall, Sheetal, Sabaredzovic, Edita, Deng, Emily, Candela, Madison, Smith, Hunter, Hobbs, Diana, Scott, Jalen, Levin, Johannes, Xiong, Chengjie, Wang, Peter, Xu, Xiong, Li, Yan, Gremminger, Emily, Ma, Yinjiao, Bui, Ryan, Lu, Ruijin, Martins, Ralph, Sosa Ortiz, Ana Luisa, Daniels, Alisha, Courtney, Laura, Mori, Hiroshi, Supnet-Bell, Charlene, Xu, Jinbin, Ringman, John, Shen, Yuanyuan, Timsina, Jigyasha, Heo, Gyujin, Beric, Aleksandra, Ali, Muhammad, Wang, Ciyang, Yang, Chengran, Wang, Yueyao, Western, Daniel, Liu, Menghan, Gorijala, Priyanka, Budde, John, Do, Anh, Liu, Haiyan, Gordon, Brian, Llibre-Guerra, Jorge J., Joseph-Mathurin, Nelly, Maschi, Dario, Wyss-Coray, Tony, Pastor, Pau, Renton, Alan E., Surace, Ezequiel I., Alvarez, Ignacio, Ringman, John M., Allegri, Ricardo Francisco, Seyfried, Nicholas, Day, Gregg S., Wu, Qisi, Fernández, M. Victoria, Tarawneh, Rawan, Morris, John C., Ibanez, Laura, Sung, Yun Ju

Publikováno v: In Cell 31 October 2024 187(22):6309-6326

Using a policy learning lens to understand health financing policy outcomes: the case of translating strategic health purchasing into policy and practice in Burkina Faso

Autor: Manuela De Allegri, Joël Arthur Kiendrébéogo, Bruno Meessen, Wim Van Damme

Publikováno v: BMJ Global Health, Vol 9, Iss 11 (2024)

Introduction Achieving universal health coverage (UHC) through an effective health financing system is a challenge for many low-income countries. Learning is key to success due to many uncertainties and unknowns. Using the case of translating strateg

Externí odkaz: https://doaj.org/article/05b2f56a28aa4210b92a6144ab9b8b38