A Microphysiological System with an Anaerobic Air-Liquid Interface and Functional Mucus Layer for Coculture of Intestinal Bacteria and Primary Human Colonic Epithelium.

Autor: Kim R; Department of Biological and Chemical Engineering, Hongik University, Sejong-si 30016, Republic of Korea., Allbritton NL; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

Publikováno v: Advanced materials interfaces [Adv Mater Interfaces] 2024 Sep 03; Vol. 11 (25). Date of Electronic Publication: 2024 Jun 19.

IL-22 promotes mucin-type O-glycosylation and MATH1 ⁺ cell-mediated amelioration of intestinal inflammation.

Autor: Singh A, Beaupre M, Villegas-Novoa C, Shiomitsu K, Gaudino SJ, Tawch S, Damle R, Kempen C, Choudhury B, McAleer JP, Sheridan BS, Denoya P, Blumberg RS, Hearing P, Allbritton NL, Kumar P

Publikováno v: Cell reports [Cell Rep] 2024 Aug 27; Vol. 43 (8), pp. 114643. Date of Electronic Publication: 2024 Aug 03.

Clostridioides difficile -mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation.

Autor: Furtado KL; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA., Plott L; Marsico Lung Institute, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA., Markovetz M; Marsico Lung Institute, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA., Powers D; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA., Wang H; Department of Bioengineering, University of Washington, Seattle, Washington, USA., Hill DB; Marsico Lung Institute, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Physics and Astronomy, College of Arts and Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Papin J; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA.; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.; Department of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA., Allbritton NL; Department of Bioengineering, University of Washington, Seattle, Washington, USA., Tamayo R; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.

Publikováno v: MSphere [mSphere] 2024 Jun 25; Vol. 9 (6), pp. e0008124. Date of Electronic Publication: 2024 Jun 05.

Bifidobacterium infantis associates with T cell immunity in human infants and is sufficient to enhance antigen-specific T cells in mice.

Autor: Nyangahu DD; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA., Happel AU; Institute of Infectious Diseases and Molecular Medicine, Department of Pathology, Division of Immunology, University of Cape Town, Cape Town, South Africa., Wendoh J; Institute of Infectious Diseases and Molecular Medicine, Department of Pathology, Division of Immunology, University of Cape Town, Cape Town, South Africa., Kiravu A; Institute of Infectious Diseases and Molecular Medicine, Department of Pathology, Division of Immunology, University of Cape Town, Cape Town, South Africa., Wang Y; Department of Bioengineering, University of Washington, Seattle, WA, USA., Feng C; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA., Plumlee C; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA., Cohen S; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA., Brown BP; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA., Djukovic D; Northwest Metabolomics Research Center, University of Washington, Seattle, WA, USA., Ganief T; Institute of Infectious Diseases and Molecular Medicine, Department of Integrative Biomedical Sciences, Division of Chemical and Systems Biology, University of Cape Town, Cape Town, South Africa., Gasper M; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA., Raftery D; Northwest Metabolomics Research Center, University of Washington, Seattle, WA, USA., Blackburn JM; Institute of Infectious Diseases and Molecular Medicine, Department of Integrative Biomedical Sciences, Division of Chemical and Systems Biology, University of Cape Town, Cape Town, South Africa., Allbritton NL; Department of Bioengineering, University of Washington, Seattle, WA, USA., Gray CM; Institute of Infectious Diseases and Molecular Medicine, Department of Pathology, Division of Immunology, University of Cape Town, Cape Town, South Africa.; Biomedical Research Institute, Division of Molecular Biology and Human Genetics, Stellenbosch University, Cape Town, South Africa., Paik J; Department of Comparative Medicine, University of Washington, Seattle, WA, USA., Urdahl KB; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.; Department of Pediatrics, School of Medicine, University of Washington, Seattle WA, USA., Jaspan HB; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.; Institute of Infectious Diseases and Molecular Medicine, Department of Pathology, Division of Immunology, University of Cape Town, Cape Town, South Africa.; Department of Pediatrics, School of Medicine, University of Washington, Seattle WA, USA.

Publikováno v: Science advances [Sci Adv] 2023 Dec 08; Vol. 9 (49), pp. eade1370. Date of Electronic Publication: 2023 Dec 08.

Analytical Techniques for Single-Cell Biochemical Assays of Lipids.

Autor: Yao M; Department of Bioengineering, University of Washington, Seattle, Washington, USA; email: yaoming@uw.edu, mvaith@uw.edu, nlallbr@uw.edu., Vaithiyanathan M; Department of Bioengineering, University of Washington, Seattle, Washington, USA; email: yaoming@uw.edu, mvaith@uw.edu, nlallbr@uw.edu., Allbritton NL; Department of Bioengineering, University of Washington, Seattle, Washington, USA; email: yaoming@uw.edu, mvaith@uw.edu, nlallbr@uw.edu.

Publikováno v: Annual review of biomedical engineering [Annu Rev Biomed Eng] 2023 Jun 08; Vol. 25, pp. 281-309. Date of Electronic Publication: 2023 Apr 17.