Single-Molecule Structure and Topology of Kinetoplast DNA Networks

Autor: Pinyao He, Allard J. Katan, Luca Tubiana, Cees Dekker, Davide Michieletto

Publikováno v: Physical Review X, Vol 13, Iss 2, p 021010 (2023)

Kinetoplast DNA (kDNA) is a two-dimensional Olympic-ring-like network of mutually linked DNA minicircles found in certain parasites called trypanosomes. Understanding the self-assembly and replication of this structure are not only major open questio

Externí odkaz: https://doaj.org/article/1b0c945aa2c34735b17c81121d51d81a

Condensin Smc2-Smc4 Dimers Are Flexible and Dynamic

Autor: Jorine M. Eeftens, Allard J. Katan, Marc Kschonsak, Markus Hassler, Liza de Wilde, Essam M. Dief, Christian H. Haering, Cees Dekker

Publikováno v: Cell Reports, Vol 14, Iss 8, Pp 1813-1818 (2016)

Structural maintenance of chromosomes (SMC) protein complexes, including cohesin and condensin, play key roles in the regulation of higher-order chromosome organization. Even though SMC proteins are thought to mechanistically determine the function o

Externí odkaz: https://doaj.org/article/f66a30d959e644dab67ab4ad0a8ce36c

Bridging-induced phase separation induced by cohesin SMC protein complexes

Autor: Allard J. Katan, Davide Marenduzzo, Frank Uhlmann, Céline Bouchoux, Davide Michieletto, Ralph de Groot, Je-Kyung Ryu, Andrea Bonato, Eugene Kim, Hon Wing Liu, Masashi Minamino, Cees Dekker

Publikováno v: Ryu, J-K, Bouchoux, C, Liu, H W, Kim, E, Minamino, M, de Groot, R, Katan, A J, Bonato, A, Marenduzzo, D, Michieletto, D, Uhlmann, F & Dekker, C 2021, ' Bridging-induced phase separation induced by cohesin SMC protein complexes ', Science Advances, vol. 7, no. 7, eabe5905, pp. 1-10 . https://doi.org/10.1126/sciadv.abe5905
Science Advances 7
Science Advances
Science Advances, 7(7)

Yeast cohesin complexes cluster onto long DNA into liquid droplets, which they accomplish by ATP-independent DNA bridging.
Structural maintenance of chromosome (SMC) protein complexes are able to extrude DNA loops. While loop extrusion constitut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c381f78a4159ebcc57cd23771649b3
https://hdl.handle.net/20.500.11820/f19845b4-25f8-4949-afa2-25958ddda101

Semi-permeability of graphene nanodrums in sucrose solution

Autor: Allard J. Katan, Peter G. Steeneken, Herre S. J. van der Zant, Robin J. Dolleman

Publikováno v: 2D Materials
2D Materials, 8(1)
2D Materials 8(1), 015031 (2021). doi:10.1088/2053-1583/abbecd

2D Materials 8(1), 015031 (2021). doi:10.1088/2053-1583/abbecd
Published by IOP Publ., Bristol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db2c180f1416bdfeffaa412a7f2b76e

The condensin holocomplex cycles dynamically between open and collapsed states

Autor: Je-Kyung, Ryu, Allard J, Katan, Eli O, van der Sluis, Thomas, Wisse, Ralph, de Groot, Christian H, Haering, Cees, Dekker

Publikováno v: Nature structuralmolecular biology. 27(12)

Structural maintenance of chromosome (SMC) protein complexes are the key organizers of the spatiotemporal structure of chromosomes. The condensin SMC complex has recently been shown to be a molecular motor that extrudes large loops of DNA, but the me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ca95c70c5f9bd56f5d906b4000169a54
https://pubmed.ncbi.nlm.nih.gov/33033391