Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Allan V. Espinosa"'
Autor:
Pierre P. Massion, Bing Zhang, S.M. Jamshedur Rahman, Allan V. Espinosa, Yong Zou, Megan D. Hoeksema, Jun Qian, Jing Wang
Supplementary Figures 1-5 - PDF file 342K, Figure S1. The IGV plot of copy number variation for 152 TCGA samples in 3q regions. The samples are in descending order according to the average expression scores. Figure S2. The effect of knockdown SENP2 e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ccd0f5fff1ff9340d3d370cab9647d
https://doi.org/10.1158/1078-0432.22449746.v1
https://doi.org/10.1158/1078-0432.22449746.v1
Autor:
Pierre P. Massion, Bing Zhang, S.M. Jamshedur Rahman, Allan V. Espinosa, Yong Zou, Megan D. Hoeksema, Jun Qian, Jing Wang
Purpose: Chromosome 3q26-29 is a critical region of genomic amplification in lung squamous cell carcinomas (SCC). Identification of candidate drivers in this region could help uncover new mechanisms in the pathogenesis and potentially new targets in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d1e49dcea3a9ecec28d5361301097b
https://doi.org/10.1158/1078-0432.c.6521738.v1
https://doi.org/10.1158/1078-0432.c.6521738.v1
Autor:
Pierre P. Massion, Bing Zhang, S.M. Jamshedur Rahman, Allan V. Espinosa, Yong Zou, Megan D. Hoeksema, Jun Qian, Jing Wang
Supplementary Tables 1-13 - PDF file 135K, Supplementary Table S1: Amplification scores and average expression scores for all paired samples based on the TCGA copy number data and gene expression data Table S2: The corr_exp_amp and corr_exp_ave for 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a364777a786127b7b7ed32fc9e2038f
https://doi.org/10.1158/1078-0432.22449743.v1
https://doi.org/10.1158/1078-0432.22449743.v1
Autor:
Leora Horn, Allan V Espinosa
Publikováno v:
Clinical Investigation. 4:55-61
Afatinib is an irreversible ErbB family blocker approved for use as first-line therapy in EGF receptor (EGFR)-positive metastatic non-small-cell lung carcinoma. Its preclinical evaluation showed a higher affinity than reversible tyrosine kinase inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d7253193c8d72da66479b56591e6055
https://doi.org/10.4155/cli.13.120
https://doi.org/10.4155/cli.13.120
Autor:
Sandya Liyanarachchi, Albert de la Chapelle, Huiling He, Allan V. Espinosa, Motoyasu Saji, Herbert Auer, Alexander Larin, Victoria Savchenko, Gary L. Francis, Vasily Vasko, William T. Scouten, Matthew D. Ringel
Publikováno v:
Proceedings of the National Academy of Sciences. 104:2803-2808
Papillary thyroid carcinomas (PTCs) that invade into local structures are associated with a poor prognosis, but the mechanisms for PTC invasion are incompletely defined, limiting the development of new therapies. To characterize biological processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a494603eb12770b62038408be4106760
https://doi.org/10.1073/pnas.0610733104
https://doi.org/10.1073/pnas.0610733104
Autor:
Pierre P. Massion, S. M. Jamshedur Rahman, Jing Wang, Rosana Eisenberg, Heidi Chen, Xiangming Ji, Bradford K. Harris, Allan V. Espinosa, Megan D. Hoeksema, Pengcheng Lu, Jun Qian, Mohamed Hassanein, Yong Zou, Fredrick T. Harris
Aberrant expression of RNA-binding proteins has profound implications for cellular physiology and the pathogenesis of human diseases such as cancer. We previously identified the Fragile X-Related 1 gene (FXR1) as one amplified candidate driver gene a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119f138d7de4a687542841b425350e30
https://europepmc.org/articles/PMC4371932/
https://europepmc.org/articles/PMC4371932/
Publikováno v:
Europe PubMed Central
British Journal of Cancer
British Journal of Cancer
Activating mutations in the gene encoding BRAF are the most commonly identified oncogenic abnormalities in papillary thyroid cancer. In vitro and in vivo models have demonstrated that overexpression of activated BRAF induces malignant transformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30aff4d9a1863677505096f54e78dc98
https://doi.org/10.1038/sj.bjc.6603520
https://doi.org/10.1038/sj.bjc.6603520
Autor:
Megan D. Hoeksema, Jing Wang, Yong Zou, Allan V. Espinosa, Bing Zhang, Jun Qian, Pierre P. Massion, Jamshedur Rahman
Purpose: Chromosome 3q26-29 is a critical region of genomic amplification in lung squamous cell carcinomas (SCC). Identification of candidate drivers in this region could help uncover new mechanisms in the pathogenesis and potentially new targets in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d972705d2422de84c2995c008f84371c
https://europepmc.org/articles/PMC3807802/
https://europepmc.org/articles/PMC3807802/
Autor:
Thomas Hielscher, Andreas Gast, Allan V. Espinosa, Rainer Claus, Dirk Schadendorf, Joseph Huang, Carl Morrison, Khelifa Arab, Christoph Plass, Rajesh Kumar, Dieter Weichenhan, Laura T. Smith, Matthew D. Ringel
Metastatic melanoma is a fatal disease due to the lack of successful therapies and biomarkers for early detection and its incidence has been increasing. Genetic studies have defined recurrent chromosomal aberrations, suggesting the location of either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d0fabbbfefc457002d50b7c2d80f92
https://www.ncbi.nlm.nih.gov/pubmed/21771727
https://www.ncbi.nlm.nih.gov/pubmed/21771727
Autor:
Motoo Shinohara, Allan V. Espinosa, Leonardo M. Porchia, Samantha K McCarty, Matthew D. Ringel, Motoyasu Saji, Yun Jae Chung
Publikováno v:
Clinicalexperimental metastasis. 26(6)
Metastasis suppressors and other regulators of cell motility play an important role in tumor invasion and metastases. We previously identified that activation of the G protein coupled receptor 54 (GPR54) by the metastasis suppressor metastin inhibits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935f7cad0c62c04978c41cfd4e83a6ed
https://pubmed.ncbi.nlm.nih.gov/19306109
https://pubmed.ncbi.nlm.nih.gov/19306109