Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Allan Shuai Huang"'
Autor:
Allan Shuai Huang, Hui San Chin, Boris Reljic, Tirta M. Djajawi, Iris K. L. Tan, Jia-Nan Gong, David A. Stroud, David C. S. Huang, Mark F. van Delft, Grant Dewson
Publikováno v:
Cell Death & Differentiation. 30:632-646
Autor:
Allan Shuai, Huang, Hui San, Chin, Boris, Reljic, Tirta M, Djajawi, Iris K L, Tan, Jia-Nan, Gong, David A, Stroud, David C S, Huang, Mark F, van Delft, Grant, Dewson
Publikováno v:
Cell death and differentiation.
Intrinsic apoptosis is principally governed by the BCL-2 family of proteins, but some non-BCL-2 proteins are also critical to control this process. To identify novel apoptosis regulators, we performed a genome-wide CRISPR-Cas9 library screen, and it
Autor:
Jia-Nan Gong, Zhen Xu, Melissa J. Call, Ming-Jie Luo, Allan Shuai Huang, Lei Liu, Tirta Mario Djajawi, Mark F. van Delft, Toru Okamoto, David C. S. Huang
Publikováno v:
Cell Death and Differentiation
MCL1, a BCL2 relative, is critical for the survival of many cells. Its turnover is often tightly controlled through both ubiquitin-dependent and -independent mechanisms of proteasomal degradation. Several cell stress signals, including DNA damage and
Autor:
Daniel S. Simpson, Jiyi Pang, Ashley Weir, Isabella Y. Kong, Melanie Fritsch, Maryam Rashidi, James P. Cooney, Kathryn C. Davidson, Mary Speir, Tirta M. Djajawi, Sebastian Hughes, Liana Mackiewicz, Merle Dayton, Holly Anderton, Marcel Doerflinger, Yexuan Deng, Allan Shuai Huang, Stephanie A. Conos, Hazel Tye, Seong H. Chow, Arfatur Rahman, Raymond S. Norton, Thomas Naderer, Sandra E. Nicholson, Gaetan Burgio, Si Ming Man, Joanna R. Groom, Marco J. Herold, Edwin D. Hawkins, Kate E. Lawlor, Andreas Strasser, John Silke, Marc Pellegrini, Hamid Kashkar, Rebecca Feltham, James E. Vince
Publikováno v:
Immunity. 55:423-441.e9
Cell death plays an important role during pathogen infections. Here, we report that interferon-γ (IFNγ) sensitizes macrophages to Toll-like receptor (TLR)-induced death that requires macrophage-intrinsic death ligands and caspase-8 enzymatic activi