Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Allan R, Thomsen"'
Autor:
René Lemcke, Christine Egebjerg, Nicolai T Berendtsen, Kristoffer L Egerod, Allan R Thomsen, Tune H Pers, Jan P Christensen, Birgitte R Kornum
Publikováno v:
eLife, Vol 12 (2023)
Infection with Influenza A virus (IAV) causes the well-known symptoms of the flu, including fever, loss of appetite, and excessive sleepiness. These responses, mediated by the brain, will normally disappear once the virus is cleared from the system,
Externí odkaz:
https://doaj.org/article/cec76aac770e4e318f69c5fd2bfa978a
Publikováno v:
Viruses, Vol 14, Iss 3, p 601 (2022)
Understanding the complexity of the T-cell epitope hierarchy in humans through mouse models can be difficult. In particular, using only one murine strain, the C57BL/6 mouse, to investigate the immune response to influenza virus infection limits our u
Externí odkaz:
https://doaj.org/article/d7f9f34b36ec4912a4d0236b885f5c7d
Autor:
Jenna L. Lobby, Ida Uddbäck, Christopher D. Scharer, Tian Mi, Jeremy M. Boss, Allan R. Thomsen, Jan P. Christensen, Jacob E. Kohlmeier
Publikováno v:
The Journal of Immunology. 209:1778-1787
Lung tissue-resident memory T cells are crucial mediators of cellular immunity against respiratory viruses; however, their gradual decline hinders the development of T cell–based vaccines against respiratory pathogens. Recently, studies using adeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e45bcb21582ea145298249c19fc21a3
https://doi.org/10.4049/jimmunol.2200082
https://doi.org/10.4049/jimmunol.2200082
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
While the brain is considered an immune-privileged site, the CNS may nevertheless be the focus of immune mediated inflammation in the case of infection and certain autoimmune diseases, e.g., multiple sclerosis. As in other tissues, it has been found
Externí odkaz:
https://doaj.org/article/0c0de643276343bf89e4da5c15d5fe81
Autor:
Susan Thrane, Kara-Lee Aves, Ida E. M Uddbäck, Christoph M. Janitzek, Julianna Han, Yuhe R. Yang, Andrew B. Ward, Thor G. Theander, Morten A. Nielsen, Ali Salanti, Allan R. Thomsen, Jan P. Christensen, Adam F. Sander
Publikováno v:
Vaccines, Vol 8, Iss 3, p 389 (2020)
Due to constant antigenic drift and shift, current influenza-A vaccines need to be redesigned and administered annually. A universal flu vaccine (UFV) that provides long-lasting protection against both seasonal and emerging pandemic influenza strains
Externí odkaz:
https://doaj.org/article/db844abcf32c44f6b247988759fd368f
Autor:
Dennis Christensen, Jan P. Christensen, Karen S. Korsholm, Louise K. Isling, Karin Erneholm, Allan R. Thomsen, Peter Andersen
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Influenza epidemics occur annually, and estimated 5–10% of the adult population and 20–30% of children will become ill from influenza infection. Seasonal vaccines primarily work through the induction of neutralizing antibodies against the princip
Externí odkaz:
https://doaj.org/article/e6d6daa11fff4912aeff848ac1384606
Autor:
Maria R Bassi, Mads A B Larsen, Michael Kongsgaard, Michael Rasmussen, Søren Buus, Anette Stryhn, Allan R Thomsen, Jan P Christensen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004464 (2016)
The live attenuated yellow fever vaccine (YF-17D) has been successfully used for more than 70 years. It is generally considered a safe vaccine, however, recent reports of serious adverse events following vaccination have raised concerns and led to su
Externí odkaz:
https://doaj.org/article/cb730bdc179240e7a5953a19b2f97a1e
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117242 (2015)
In this study, we compared adenoviral vaccine vectors with the capacity to induce equally potent immune responses against non-dominant and immunodominant epitopes of murine lymphocytic choriomeningitis virus (LCMV). Our results demonstrate that vacci
Externí odkaz:
https://doaj.org/article/d1119242887f4c2f8eaea47939a28513
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87831 (2014)
Skin cancer is the most common type of all cancers. However, it comprises several different types of cancers, one of which is malignant melanoma. Even though melanomas only make up about 5% of skin cancers, they are responsible for the majority of sk
Externí odkaz:
https://doaj.org/article/f71a5c390951464e918fa57e1338854a
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66081 (2013)
It has previously been found that combination therapy with anti-CTLA-4 and anti-4-1BB antibodies may enhance tumor immunity. However, this treatment is not efficient against all tumors, and it has been suggested that variations in tumor control may r
Externí odkaz:
https://doaj.org/article/1d498ace87d84a57ab27548affe0c64a