Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Allan McI. Mowat"'
Autor:
Simone Isling Pærregaard, Line Wulff, Sophie Schussek, Kristoffer Niss, Urs Mörbe, Johan Jendholm, Kerstin Wendland, Anna T. Andrusaite, Kevin F. Brulois, Robert J. B. Nibbs, Katarzyna Sitnik, Allan McI Mowat, Eugene C. Butcher, Søren Brunak, William W. Agace
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The intestinal lamina propria contains a diverse network of fibroblasts that provide key support functions to cells within their local environment. Despite this, our understanding of the diversity, location and ontogeny of fibroblasts within
Externí odkaz:
https://doaj.org/article/87335917aa2d431bbb6623c43b0f8bbc
Autor:
Simone Isling Pærregaard, Line Wulff, Sophie Schussek, Kristoffer Niss, Urs Mörbe, Johan Jendholm, Kerstin Wendland, Anna T. Andrusaite, Kevin F. Brulois, Robert J. B. Nibbs, Katarzyna Sitnik, Allan McI Mowat, Eugene C. Butcher, Søren Brunak, William W. Agace
Publikováno v:
Nature Communications. 14
The intestinal lamina propria contains a diverse network of fibroblasts that provide key support functions to cells within their local environment. Despite this, our understanding of the diversity, location and ontogeny of fibroblasts within and alon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a48ba203dc33fb63c63c73e3546807ab
https://doi.org/10.1038/s41467-023-37952-5
https://doi.org/10.1038/s41467-023-37952-5
Autor:
Allan McI. Mowat
Publikováno v:
Journal of Leukocyte Biology. 109:513-517
Metchnikoff’s essay, Intestinal Bacteriotherapy, was written when the study of microbiology was still in its infancy and few intestinal diseases had been ascribed to a specific bacterial infection. Metchnikoff offered perceptive ideas that have bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5431e81bf54d43b082df306b9748bc8
https://doi.org/10.1002/jlb.4ri0920-599
https://doi.org/10.1002/jlb.4ri0920-599
Autor:
Telma Lança, Jonas Ungerbäck, Clément Da Silva, Thorsten Joeris, Fatemeh Ahmadi, Julien Vandamme, Marcus Svensson-Frej, Allan McI Mowat, Knut Kotarsky, Mikael Sigvardsson, William W. Agace
Publikováno v:
Lança, T, Ungerbäck, J, Da Silva, C, Joeris, T, Ahmadi, F, Vandamme, J, Svensson-Frej, M, Mowat, A M I, Kotarsky, K, Sigvardsson, M & Agace, W W 2022, ' IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage ', Immunity, vol. 55, no. 8, pp. 1431-1447.e11 . https://doi.org/10.1016/j.immuni.2022.06.006
Conventional dendritic cells (cDCs) consist of two major functionally and phenotypically distinct subsets, cDC1 and cDC2, whose development is dependent on distinct sets of transcription factors. Interferon regulatory factor 8 (IRF8) is required at m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa86f4772b068f92f822991e8ba661f
https://orbit.dtu.dk/en/publications/63adde2f-e070-437d-82eb-7cb771ca08cd
https://orbit.dtu.dk/en/publications/63adde2f-e070-437d-82eb-7cb771ca08cd
Autor:
Daniel R. Gaya, Simon Milling, Hannah M Baer, Elizabeth McDonald, Allan McI. Mowat, Slater L. Clay, Calum C. Bain, Umer Zeeshan Ijaz, Alberto Bravo-Blas, Anna Heawood, Pamela B. Wright, F. Morton, Jagtar Singh Nijjar, Elaine V Robertson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
To understand the contribution of mononuclear phagocytes (MNP), which include monocyte-derived intestinal macrophages, to the pathogenesis of inflammatory bowel disease (IBD), it is necessary to identify functionally-different MNP populations. We aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd220f15530017e76972d0cf0a929102
http://europepmc.org/articles/PMC8490356
http://europepmc.org/articles/PMC8490356
Autor:
Katarzyna M. Sitnik, S. I. Paerregaard, Kerstin Wendland, Johan Jendholm, U. Moerbe, Robert J. B. Nibbs, Kevin Brulois, Eugene C. Butcher, L. Wulff, Anna Andrusaite, William W. Agace, Søren Brunak, Kristoffer Niss, S. Schussek, Allan McI. Mowat
SummaryIntestinal fibroblasts (FB) play essential roles in intestinal homeostasis. Here we show that the small and large intestinal lamina propria (LP) contain similar FB subsets that locate in specific anatomical niches and express distinct arrays o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53f95821e56e3c5f19667eb7522dfba9
https://doi.org/10.1101/2021.08.13.456086
https://doi.org/10.1101/2021.08.13.456086
Autor:
Luisa Klotz, Aaron Silva-Sanchez, Troy D. Randall, Knut Kotarsky, Simon Tavernier, Cristina Gomez-Casado, Thorsten Joeris, Bernard Malissen, Petra Holmkvist, William W. Agace, Allan McI. Mowat
Publikováno v:
Science Immunology
Science Immunology, 2021, 6 (60), ⟨10.1126/sciimmunol.abd3774⟩
Science Immunology, 2021, 6 (60), ⟨10.1126/sciimmunol.abd3774⟩
Although CD8+ T cell tolerance to tissue-specific antigen (TSA) is essential for host homeostasis, the mechanisms underlying peripheral cross-tolerance and whether they may differ between tissue sites remain to be fully elucidated. Here, we demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6e9ed5af70c09a33643388be71f3b1
https://doi.org/10.1126/sciimmunol.abd3774
https://doi.org/10.1126/sciimmunol.abd3774
Autor:
Allan McI. Mowat, Calum C. Bain
Publikováno v:
Mucosal Immunology
Cell
Cell
Summary The colon is primarily responsible for absorbing fluids. It contains a large number of microorganisms including fungi, which are enriched in its distal segment. The colonic mucosa must therefore tightly regulate fluid influx to control absorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4af442367ce617ea1ace7ee62b861a4
https://eprints.gla.ac.uk/227589/1/227589.pdf
https://eprints.gla.ac.uk/227589/1/227589.pdf
Autor:
Mikael Sigvardsson, Thorsten Joeris, Marcus Svensson-Frej, William W. Agace, Fatemeh Ahmadi, Julien Vandamme, Allan McI. Mowat, Jonas Ungerbäck, Clément Da Silva, Telma Lança
Publikováno v:
SSRN Electronic Journal.
Conventional dendritic cells (cDC) consist of two functionally and phenotypically distinct subsets, cDC1 and cDC2, whose development is dependent on distinct sets of transcription factors. Interferon regulatory factor 8 (IRF8) is required at multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61b2b62ea6d4451e5adf3d40617d7d5c
https://doi.org/10.2139/ssrn.3813286
https://doi.org/10.2139/ssrn.3813286
Autor:
Daniel M. Wall, Simon Milling, Hannah M. Wessel, Susan M. Mason, Alberto Bravo-Blas, Allan McI. Mowat, Michael J. Ormsby, Heather Hulme, Stephen W.G. Tait, Síle A. Johnson, Anne McIntosh, Karen Blyth, Seth B. Coffelt
The use of bacteria as an alternative cancer therapy has been re-investigated in recent years. A number of bacterial strains for this purpose have been generated, one of which is SL7207: an auxotrophic Salmonella enterica serovar Typhimurium aroA mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4498723f4b3b038646b3d27afe1cbf50
https://doi.org/10.1101/2020.05.13.092858
https://doi.org/10.1101/2020.05.13.092858