Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Allan K. Hansen"'
Autor:
Paul Cumming, André H. Dias, Lars C. Gormsen, Allan K. Hansen, Ian Alberts, Axel Rominger, Ole L. Munk, Hasan Sari
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Background Until recently, quantitation of the net influx of 2-[18F]fluorodeoxyglucose (FDG) to brain (K i) and the cerebrometabolic rate for glucose (CMRglc) required serial arterial blood sampling in conjunction with dynamic positron emiss
Externí odkaz:
https://doaj.org/article/0f3d9f1c3dbe43708a12da22585cbf74
Autor:
Niels Okkels, Jacob Horsager, Miguel A. Labrador-Espinosa, Frederik O. Hansen, Katrine B. Andersen, Mie Kristine Just, Tatyana D. Fedorova, Casper Skjærbæk, Ole L. Munk, Kim V. Hansen, Hanne Gottrup, Allan K. Hansen, Michel J. Grothe, Per Borghammer
Publikováno v:
NeuroImage, Vol 269, Iss , Pp 119908- (2023)
Introduction: [18F]fluoroetoxybenzovesamicol ([18F]FEOBV) is a positron emission topography (PET) tracer for the vesicular acetylcholine transporter (VAChT), a protein located predominantly in synaptic vesicles in cholinergic nerve terminals. We aime
Externí odkaz:
https://doaj.org/article/caac9405089a4f35a1aa5b913d872eba
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Background Dynamic whole-body (D-WB) FDG PET/CT is a recently developed technique that allows direct reconstruction of multiparametric images of metabolic rate of FDG uptake (MRFDG) and “free” FDG (DVFDG). Multiparametric images have a m
Externí odkaz:
https://doaj.org/article/efe705a450604ea39e0a224b30faca17
Autor:
Rola Ismail, Peter Parbo, Lasse Stensvig Madsen, Allan K. Hansen, Kim V. Hansen, Jeppe L. Schaldemose, Pernille L. Kjeldsen, Morten G. Stokholm, Hanne Gottrup, Simon F. Eskildsen, David J. Brooks
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background The aim of this longitudinal study was to assess with positron emission tomography (PET) the relationship between levels of inflammation and the loads of aggregated β-amyloid and tau at baseline and again after 2 years in prodrom
Externí odkaz:
https://doaj.org/article/d6cbb349346a47e69fbe4d108ae94551
Autor:
Louise Devantier, Allan K. Hansen, Jens-Jacob Mølby-Henriksen, Michael Pedersen, Per Borghammer, Therese Ovesen, Måns Magnusson
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background: Ménière's disease (MD) is a chronic peripheral vestibular disorder with recurrent episodes of vertigo accompanied by fluctuating hearing loss, tinnitus and aural fullness in the affected ear. There are several unanswered fundamental que
Externí odkaz:
https://doaj.org/article/9253e130fbbd46929cfebf3cb848c5fa
Autor:
Louise Devantier, Allan K. Hansen, Jens-Jacob Mølby-Henriksen, Christian Bech Christensen, Tina Lildal, Michael Pedersen, Måns Magnusson, Per Borghammer, Therese Ovesen
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Introduction: The cortical metabolic activity in patients with Menière's disease has not been investigated. The aim of this study was to investigate the 18F-FDG cerebral uptake in Menière's patients compared to healthy controls.Method: Eight patien
Externí odkaz:
https://doaj.org/article/0369b537a9fd40cda686ecf736fe4e8f
Autor:
Peter Parbo, Rola Ismail, Michael Sommerauer, Morten G. Stokholm, Allan K. Hansen, Kim V. Hansen, Ali Amidi, Jeppe L. Schaldemose, Hanne Gottrup, Hans Brændgaard, Simon F. Eskildsen, Per Borghammer, Rainer Hinz, Joel Aanerud, David J. Brooks
Publikováno v:
Neurobiology of Disease, Vol 117, Iss , Pp 211-216 (2018)
Objective: Our aim was to assess with positron emission tomography (PET) the temporal and spatial inter-relationships between levels of cortical microglial activation and the aggregated amyloid-β and tau load in mild cognitive impairment (MCI) and e
Externí odkaz:
https://doaj.org/article/5538e535c0454476a035cf05a4b9006c
Autor:
Rola Ismail, Allan K. Hansen, Peter Parbo, Hans Brændgaard, Hanne Gottrup, David J. Brooks, Per Borghammer
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2018 (2018)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder. AD pathology is characterized by abnormal aggregation of the proteins amyloid-β (Aβ) and hyperphosphorylated tau. No effective disease modifying therapies are currently availab
Externí odkaz:
https://doaj.org/article/e743e93a6fe84b2e9bf1814ced17114c
Autor:
Christopher E.J. Doppler, Julia Smit, Maximilian Hommelsen, Aline Seger, Niels Okkels, Jacob Horsager, Martin Kinnerup, Allan K. Hansen, Tatyana D. Fedorova, Karoline Knudsen, Marit Otto, Adjmal Nahimi, Gereon R. Fink, Per Borghammer, Michael Sommerauer
Publikováno v:
Doppler, C E J, Smit, J, Hommelsen, M, Seger, A, Okkels, N, Horsager, J, Kinnerup, M, Hansen, A K, Fedorova, T D, Knudsen, K, Otto, M, Nahimi, A, Fink, G R, Borghammer, P & Sommerauer, M 2022, ' Disruption of Sleep Microarchitecture Is a Sensitive and Early Marker of Parkinson's Disease ', Journal of Parkinson's Disease, vol. 12, no. 8, pp. 2555-2560 . https://doi.org/10.3233/JPD-223442
BACKGROUND: Although sleep disturbances are highly prevalent in patients with Parkinson's disease, sleep macroarchitecture metrics show only minor changes.OBJECTIVE: To assess alterations of the cyclic alternating pattern (CAP) as a critical feature
Autor:
Jacob Horsager, Niels Okkels, Allan K. Hansen, Malene F. Damholdt, Katrine H. Andersen, Tatyana D. Fedorova, Ole Lajord Munk, Erik H. Danielsen, Nicola Pavese, David J. Brooks, Per Borghammer
Publikováno v:
Horsager, J, Okkels, N, Hansen, A K, Damholdt, M F, Andersen, K H, Fedorova, T D, Munk, O L, Danielsen, E H, Pavese, N, Brooks, D J & Borghammer, P 2022, ' Mapping Cholinergic Synaptic Loss in Parkinson's Disease : An [18F]FEOBV PET Case-Control Study ', Journal of Parkinson's Disease, vol. 12, no. 8, pp. 2493-2506 . https://doi.org/10.3233/JPD-223489
BACKGROUND: Cholinergic degeneration is strongly associated with cognitive decline in patients with Parkinson's disease (PD) but may also cause motor symptoms and olfactory dysfunction. Regional differences are striking and may reflect different PD r