Prevalence of antiretroviral therapy treatment failure among HIV-infected pregnant women at first antenatal care: PMTCT Option B+ in Malawi.

Autor: Maganizo B Chagomerana, William C Miller, Jennifer H Tang, Irving F Hoffman, Bryna J Harrington, Bethany DiPrete, Shaphil Wallie, Allan Jumbe, Laura Limarzi, Mina C Hosseinipour

Publikováno v: PLoS ONE, Vol 13, Iss 12, p e0209052 (2018)

BACKGROUND:In Malawi's PMTCT Option B+ program, HIV-infected pregnant women who are already receiving ART are continued on their current therapy regimen without testing for treatment failure at the first antenatal care (ANC) visit. HIV RNA screening

Externí odkaz: https://doaj.org/article/673da448aca443339ff798d26d8abc5c

Locally contextualizing understandings of depression, the EPDS, and PHQ-9 among a sample of postpartum women living with HIV in Malawi

Autor: Bryna J Harrington, William C. Miller, Laura Limarzi Klyn, Allan Jumbe, Vivian F. Go, Brian W. Pence, Laura M. Ruegsegger, Bradley N. Gaynes, Madalitso Maliwichi, Annie Thom, Melissa Stockton, Christopher F. Akiba, Joanna Maselko, Mina C. Hosseinipour

Publikováno v: J Affect Disord

Background: The Edinburgh Postnatal Depression Scale (EPDS) and Patient Health Questionnaire-9 (PHQ-9) are widely used depression screening tools, yet perceptions and understandings of their questions and of depression are not well defined in cross-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424a17ddf901bbb625d0ab0ad3c88fc0
https://pubmed.ncbi.nlm.nih.gov/33272687

Probable antenatal depression at antiretroviral initiation and postpartum viral suppression and engagement in Option B+

Autor: Allan Jumbe, William C. Miller, Bradley N. Gaynes, Ntchindi A Gondwe, Mina C. Hosseinipour, Joanna Maselko, Shaphil D Wallie, S Study team, Bryna J Harrington, Madalitso Maliwichi, Brian W. Pence

Objective To estimate the association of probable antenatal depression with postpartum HIV care engagement among pregnant women in Malawi. Design We conducted a prospective cohort study of 299 women who were initiating antiretroviral therapy (ART) th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640bc79a22eab8cf5c41b329e88d21b1
https://europepmc.org/articles/PMC6528829/

Optimizing prevention of HIV mother to child transmission: Duration of antiretroviral therapy and viral suppression at delivery among pregnant Malawian women

Autor: William C. Miller, Jennifer H. Tang, Mathias John, Maganizo Chagomerana, Mina C. Hosseinipour, Allan Jumbe, Irving F. Hoffman, Jacob Phulusa, Bryan C. Mthiko

Publikováno v: PLoS ONE, Vol 13, Iss 4, p e0195033 (2018)
PLoS ONE

BackgroundEffective antiretroviral therapy during pregnancy minimizes the risk of vertical HIV transmission. Some women present late in their pregnancy for first antenatal visit; whether these women achieve viral suppression by delivery and how suppr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e553f327e9c494879bfcbf314157e6d
https://doaj.org/article/ea451e04bc134b4aa557cf993abd325c

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

Autor: Jahit Sacarlal, Agnes Akoth Onyango, Jackton Omoto, Portia Kamthunzi, Norbert Awino, Samuel Ayamba, Yolanda Guerra, Tisungane Mvalo, Diana Quelhas, Daniel Ansong, Didier Leboulleux, Béatrice Peggy Abossolo, Halidou Tinto, Dalitso Nyakuipa, Tsiri Agbenyega, Victorine Owira, Roma Chilengi, Kingsley Kayan, David Sambian, Terrell Carter, Ali Ali, Martha M. Lemnge, Cornelia Conzelmann, Seth Owusu-Agyei, Quique Bassat, Jean-Bosco Ouédraogo, William Kabore, José Francisco Fernandes, Chris Drakeley, Peter G. Kremsner, Afiya Radford, Saadou Issifou, Philip Bejon, Umberto D'Alessandro, Christian Loucq, Chris Odero, Francisca Machera, Pedro L. Alonso, Ali Mtoro, Theresa Rettig, John Lusingu, Albans Msika, Kwaku Poku Asante, Brian Greenwood, Alex Agyekum, George Adjei, Ruth Wasuna, Innocent Valea, Ali Hamad, Irving F. Hoffman, Rose Minja, Nelecy Chome, John Williamson, Charity Maingi, Salim Abdulla, Omar Juma, Amanda J. Leach, Stacey M. O. Gondi, W. Ripley Ballou, Mwanajaa Shomari, Johan Vekemans, Opokua Ofori-Anyinam, Hermann Sorgho, Samwel Gesase, Myriam Bruls, Allan Otieno, Barbara Gaelle Nfono Ondo Methogo, Kephas Otieno, David Dosoo, Benjamin Mordmüller, Walter Otieno, John J. Aponte, Yannick Doucka, Bertrand Lell, Didier Lapierre, Joe Cohen, Selidji T Agnandji, Coline Mahende, Alwisa Urassa, Lucas Otieno, Sofia Mandjate, David B. Jones, Samuel Adjei, Mary J. Hamel, Martina Oneko, Bernhards Ogutu, Hassan Kilavo, Marla Sillman, Isaac Asante, Ruth Owusu-Ofori, Preeti Vansadia, Laurence Slutsker, Sayouba Ouedraogo, John Bawa, Christine Kerubo, Omari Abdul, Pedro Aide, Justice Sylverken, Marcel Tanner, Barbara Savarese, David Schellenberg, Marc Christian Tahita, Norbert Peshu, Yara Sandrine, Owusu Boahen, Ruthendo Nkomo, Benjamin Tsofa, Kayla F. Laserson, Patricia Njuguna, Pauline Akoo, Joseph Chintedza, Grace Mwangoka, Miguel A. Lanaspa, Robert T. Guiguemdé, Erik Jongert, Allan Jumbe, Larko Owusu, Thor G. Theander, Alma Sykes, Francis Martinson, Edwin Liheluka, Eusebio Macete, Kingsley Osei-Kwakye, Marc Lievens, Saumu Ahmed, Nahya Salim, Otsyula Nekoye, Arlindo Nhamuave, Kafuruki Shubis, Kevin Marsh, Ally Olotu, Trudie Lang, Harry Owusu Boateng, Anangisye Malabeja, Arnaud Flamen, Simon Kariuki, Solange Soulanoudjingar, Jesse Gitaka, Vincent Muturi-Kioi, Daniel Chandramohan

Publikováno v: New England Journal of Medicine. 365:1863-1875

BACKGROUND An ongoing phase 3 study of the efficacy, safety, and immunogenicity of candidate malaria vaccine RTS,S/AS01 is being conducted in seven African countries. METHODS From March 2009 through January 2011, we enrolled 15,460 children in two ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c16dced5eb2fd8989f7492b258232d8
https://doi.org/10.1056/nejmoa1102287