Zobrazeno 1 - 10
of 532
pro vyhledávání: '"Allan J. Pantuck"'
Autor:
Gavin Hui, Dimitrios Stefanoudakis, Yuliya Zektser, Dayna Jill Isaacs, Christopher Hannigan, Allan J. Pantuck, Alexandra Drakaki
Publikováno v:
Current Oncology, Vol 30, Iss 8, Pp 7398-7411 (2023)
Bladder cancer is one of the most commonly diagnosed genitourinary malignancies. For many years, the primary treatment for metastatic urothelial cancer (mUC) was predicated on the use of platinum-based chemotherapy. More recently, immune checkpoint i
Externí odkaz:
https://doaj.org/article/2eb8acf1faca4470bee76f1c879a8978
Autor:
Brian I. Rini, Dena Battle, Robert A. Figlin, Daniel J. George, Hans Hammers, Tom Hutson, Eric Jonasch, Richard W. Joseph, David F. McDermott, Robert J. Motzer, Sumanta K. Pal, Allan J. Pantuck, David I. Quinn, Virginia Seery, Martin H. Voss, Christopher G. Wood, Laura S. Wood, Michael B. Atkins
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-20 (2019)
Abstract The approval of immunotherapeutic agents and immunotherapy-based combination strategies in recent years has revolutionized the treatment of patients with advanced renal cell carcinoma (aRCC). Nivolumab, a programmed death 1 (PD-1) immune che
Externí odkaz:
https://doaj.org/article/eee5402a5743458ab14e581acfdc6861
Autor:
Tobias Klatte, Kevin M. Gallagher, Luca Afferi, Alessandro Volpe, Nils Kroeger, Silvia Ribback, Alan McNeill, Antony C. P. Riddick, James N. Armitage, Tevita F. ‘Aho, Tim Eisen, Kate Fife, Axel Bex, Allan J. Pantuck, Grant D. Stewart
Publikováno v:
BMC Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background The current World Health Organization classification recognises 12 major subtypes of renal cell carcinoma (RCC). Although these subtypes differ on molecular and clinical levels, they are generally managed as the same disease, simp
Externí odkaz:
https://doaj.org/article/881cc95bca894f10a09de5f52493ef70
Publikováno v:
Asian Journal of Urology, Vol 2, Iss 1, Pp 38-45 (2015)
Objective: Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC) and is characterized by biallelic inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene. One effect of VHL inactivation is hypoxia
Externí odkaz:
https://doaj.org/article/3b59a0a31e804efc935950b70318d96c
Autor:
Michael B. Atkins, David F. McDermott, David I. Quinn, Thomas Olencki, Thomas Hutson, Brian I. Rini, Laura S. Wood, Martin H. Voss, Hans Hammers, William Bro, Ronald M. Bukowski, Bernard Faba, Jo Faba, Robert A. Figlin, Eric Jonasch, Richard W. Joseph, Bradley C. Leibovich, Allan J. Pantuck, Virginia Seery, Christopher G. Wood
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 4, Iss 1 (2016)
Immunotherapy has produced durable clinical benefit in patients with metastatic renal cell cancer (RCC). In the past, patients treated with interferon-alpha (IFN) and interleukin-2 (IL-2) have achieved complete responses, many of which have lasted fo
Externí odkaz:
https://doaj.org/article/e2cf889874654be18d4dbbdd7a7a921c
Autor:
Behfar Ehdaie, Clare M Tempany, Ford Holland, Daniel D Sjoberg, Adam S Kibel, Quoc-Dien Trinh, Jeremy C Durack, Oguz Akin, Andrew J Vickers, Peter T Scardino, Dan Sperling, Jeffrey Y C Wong, Bertram Yuh, David A Woodrum, Lance A Mynderse, Steven S Raman, Allan J Pantuck, Marc H Schiffman, Timothy D McClure, Geoffrey A Sonn, Pejman Ghanouni
Publikováno v:
Lancet Oncol
Men with grade group 2 or 3 prostate cancer are often considered ineligible for active surveillance; some patients with grade group 2 prostate cancer who are managed with active surveillance will have early disease progression requiring radical thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ed6b42ffc7ec1c4bfb4e49ddacde36
https://doi.org/10.1016/s1470-2045(22)00251-0
https://doi.org/10.1016/s1470-2045(22)00251-0
Autor:
Nils Kroeger, Cédric Lebacle, Justine Hein, P.N. Rao, Reza Nejati, Shuanzeng Wei, Martin Burchardt, Alexandra Drakaki, Marshall Strother, Alexander Kutikov, Robert Uzzo, Allan J. Pantuck
Publikováno v:
European Journal of Cancer. 168:68-76
To elucidate which patients with clear cell renal cell carcinoma have the highest risk for disease relapse after curative nephrectomy is challenging but is acutely relevant in the era of approved adjuvant therapies. Pathological and genetic markers w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f07c9d8e23fb4c7c2c50a37ffd77ae
https://doi.org/10.1016/j.ejca.2022.03.023
https://doi.org/10.1016/j.ejca.2022.03.023
Autor:
Alexandra Drakaki, Dennis J. Slamon, Dimitrios Iliopoulos, Vassilis Georgoulias, Allan J. Pantuck, Shawnt Issakhanian, Tong Luo, Artin Soroosh, Christina Vorvis, Swapna Mahurkar-Joshi, Filippos Koinis, Neil O'Brien, Hsiao-Wang Chen, Marina Koutsioumpa
Supplementary Figure S1. PPP2R2A mRNA levels in the excised tumors from 5637 bearing mouse xenografts. Supplementary Figure S2. PPP2R2A mRNA and protein levels upon transient silencing.Supplementary Figure S3. PPP2R2A protein levels upon transient ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec9b28d868bcc1667181d942a073ae9
https://doi.org/10.1158/1535-7163.22505146.v1
https://doi.org/10.1158/1535-7163.22505146.v1
Autor:
Alexandra Drakaki, Dennis J. Slamon, Dimitrios Iliopoulos, Vassilis Georgoulias, Allan J. Pantuck, Shawnt Issakhanian, Tong Luo, Artin Soroosh, Christina Vorvis, Swapna Mahurkar-Joshi, Filippos Koinis, Neil O'Brien, Hsiao-Wang Chen, Marina Koutsioumpa
Bladder cancer represents a disease associated with significant morbidity and mortality. MiR-21 has been found to have oncogenic activity in multiple cancers, including bladder cancer, whereas inhibition of its expression suppresses tumor growth. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ba50fe86c1965b673e352b45bd603c3
https://doi.org/10.1158/1535-7163.c.6537967.v1
https://doi.org/10.1158/1535-7163.c.6537967.v1
Autor:
Brian Shuch, Allan J. Pantuck, Jean-Christophe Bernhard, Michael A. Morris, Viraj Master, Andrew Scott, Charles van Praet, Clement Bailly, Bülent Önal, Tamer Aksoy, Robin Merkx, David M. Schuster, Sze Ting Lee, Neeta Pandit-Taskar, Alice C. Fan, Libuse Tauchmanova, Karl Schmidt, Kavita Vadali, Colin Hayward, Peter Mulders
Publikováno v:
Journal of Urology. 209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c08c47258a9b68b400895b615653997
https://doi.org/10.1097/ju.0000000000003426.01
https://doi.org/10.1097/ju.0000000000003426.01