Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Allan G.A. Coombes"'
Publikováno v:
Journal of Microencapsulation. 36:204-214
Nigella sativa extract (NSE) was incorporated in alginate microcapsules using aerosolisation and homogenisation methods, respectively, with the aim of delivering high concentrations of the active s...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a271691270ca82ad3a195279845a9d3
https://doi.org/10.1080/02652048.2019.1620356
https://doi.org/10.1080/02652048.2019.1620356
Polycaprolactone (PCL) matrices incorporating lactoferrin as a natural macromolecular microbicide, were prepared by rapidly cooling a suspension of lactoferrin particulates in PCL solution to induce crystallisation and hardening of the polymer. Therm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37b7a0708e90ccecc91ecc93280412b
https://hdl.handle.net/11541.2/141581
https://hdl.handle.net/11541.2/141581
Publikováno v:
Journal of Drug Delivery Science and Technology. 46:384-391
Capsules containing indomethacin as a model, poorly water-soluble drug, were produced using the unconventional high-M alginate polymer for site-specific drug delivery in the GI tract. Hydrated Calcium (Ca)-alginate capsules (3 mm diameter), produced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c981babfe2522d41af71de1236b1d9b7
https://doi.org/10.1016/j.jddst.2018.05.024
https://doi.org/10.1016/j.jddst.2018.05.024
Publikováno v:
International Journal of Pharmaceutics. 607:121026
Oral delivery of anticancer drug-loaded nanoparticles (NPs) to the colon offers opportunities to improve colorectal cancer (CRC) treatment by increasing the free drug concentration at tumour sites and/or enhancing NP accumulation in tumours. Indometh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0134f68a4c264c22a9005b143a4696b
https://doi.org/10.1016/j.ijpharm.2021.121026
https://doi.org/10.1016/j.ijpharm.2021.121026
Publikováno v:
Journal of Pharmaceutical Sciences. 106:208-216
Alginate microparticles incorporating hydrocortisone hemisuccinate were produced by aerosolization and homogenization methods to investigate their potential for colonic drug delivery. Microparticle stabilization was achieved by CaCl2 crosslinking sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1d5ad46de264f15432e795acb44295
https://doi.org/10.1016/j.xphs.2016.08.015
https://doi.org/10.1016/j.xphs.2016.08.015
Autor:
Hevanshi Vidhushika Fernando, Allan G.A. Coombes, H Banneheke, Li Li Chan, Nhung Dang, Sivalingam Nalliah, Diviya Santhanes
Publikováno v:
Pharmaceutical development and technology. 24(3)
Microporous polymeric matrices prepared from poly(ɛ-caprolactone) [PCL] were evaluated for controlled vaginal delivery of the antiprotozoal agent (tinidazole) in the treatment of the sexually transmitted infection, trichomoniasis. The matrices were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1802168776ccd581fad12f93d9c71d
https://pubmed.ncbi.nlm.nih.gov/29799300
https://pubmed.ncbi.nlm.nih.gov/29799300
Publikováno v:
European Journal of Lipid Science and Technology. 118:1193-1201
Novel alkyds of short, medium, and long oil length were synthesized using a two-stage alcoholysis-polyesterification method from bio-sourced starting materials. Alcoholysis reaction mixtures of palm kernel oil and glycerol underwent transesterificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaac1f117ced955b9fe4858e3e7d29b7
https://doi.org/10.1002/ejlt.201500456
https://doi.org/10.1002/ejlt.201500456
Autor:
Meenakshi Pathak, Kathryn J. Steadman, Allan G.A. Coombes, Mark S. Turner, Dongjie Wang, Cheryn Palmer
Publikováno v:
Journal of Pharmaceutical Sciences. 104:4217-4222
Polycaprolactone (PCL) matrices loaded with doxycycline were produced by rapidly cooling suspensions of the drug powder in PCL solution in acetone. Drug loadings of 5%, 10%, and 15% (w/w) of the PCL content were achieved. Exposure of doxycycline powd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a9170b7ee7afd33a8cbc7c8456d12a
https://doi.org/10.1002/jps.24652
https://doi.org/10.1002/jps.24652
Autor:
Siang Yin Lee, Allan G.A. Coombes, Ching Lin Ong, Huey Lin Ong, Michael J. Rathbone, Seng Neon Gan, Siew Yong Teo
Publikováno v:
Journal of Nanomaterials, Vol 2015 (2015)
Novel oil-in-water (O/W) nanoemulsions were formulated using short, medium, and long oil length alkyds synthesized from palm kernel oil by a two-stage alcoholysis-polyesterification reaction. Alkyd/surfactant/water ternary phase diagrams identified a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc42ceb4c089af264f59f1530d2c4ce
https://doi.org/10.1155/2015/537598
https://doi.org/10.1155/2015/537598
Autor:
BoMi Ryu, Kathryn J. Steadman, Meenakshi Pathak, Dongjie Wang, Peter J. Cabot, Cheryn Palmer, Mark S. Turner, Allan G.A. Coombes
Publikováno v:
Journal of pharmaceutical sciences. 107(3)
Poly(ɛ-caprolactone) (PCL) intravaginal matrices were produced for local delivery of a combination of antibacterials, by rapidly cooling a mixture of drug powders dispersed in PCL solution. Matrices loaded with different combinations of metronidazol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a78f4399f001622440b94d6621fe34b
https://pubmed.ncbi.nlm.nih.gov/29100864
https://pubmed.ncbi.nlm.nih.gov/29100864