Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Allan Fleming"'
Autor:
Allan Fleming, Omar S. Aljitawi, Sunil Abhyankar, Travis Williams, Jianghua He, Heather Male, Siddhartha Ganguly, Joseph P. McGuirk, Tara L. Lin
Publikováno v:
Cancer Medicine
In addition to cytogenetics, additional molecular markers of prognosis have been identified and incorporated into the management of patients with acute myeloid leukemia (AML). We hypothesized that rates of molecular testing would be higher in an acad
Autor:
Suman Kambhampati, Ruben Reyes, Kapil N. Bhalla, Joseph P. McGuirk, Catherine Dutreix, Jo Wick, Casey Williams, Sunil Abhyankar, Allan Fleming, S Ganguly, Warren Fiskus, Omar S. Aljitawi
Publikováno v:
Pharmacotherapy. 33(12)
Purpose To determine the preclinical activity, clinical maximum tolerated dose (MTD), and recommended phase II dose of midostaurin (MS) combined either sequentially or concurrently with intravenous decitabine (DAC) in newly diagnosed patients 60 year
Autor:
Allan Fleming, Sneha Phadke
Publikováno v:
Kansas Journal of Medicine. 4
immunologic destruction of erythrocytes and can be life-threatening. • AIHA may be idiopathic, however, it should prompt a work-up for secondary causes. • Evaluation consists of a reticulocyte count, LDH, haptoglobin, indirect bilirubin, direct a
Autor:
Cole R Spresser, Allan Fleming
Publikováno v:
Kansas Journal of Medicine. 4
Autor:
Allan Fleming, Joseph P. McGuirk, Travis Williams, Heather Male, Tara L. Lin, Omar S. Aljitawi, Sunil Abhyankar, Siddhartha Ganguly
Publikováno v:
Journal of Clinical Oncology. 32:e18016-e18016
e18016 Background: Historically, cytogenetics has been the most significant predictor of outcome in Acute Myeloid Leukemia (AML). In 2008, the WHO revised its classification to recognize molecular ...
Autor:
Ramesh Balusu, Allan Fleming, Kapil N. Bhalla, Joseph P. McGuirk, Siddhartha Ganguly, Warren Fiskus, Uma Mudunuru, Heather Male, Casey Williams, Josiah Cox, Sunil Abhyankar, Stacey Hembruff, Rekha Rao, Ruben Reyes
Publikováno v:
Blood. 118:733-733
Abstract 733 NPM1 is a nucleolar phosphoprotein that functions as an oligomeric molecular chaperone for both proteins and nucleic acids. NPM1 is mutated in approximately one-third of patients with AML, especially those with the normal karyotype. The
Autor:
Allan Fleming, Sunil Abhyankar, Joseph P. McGuirk, Siddhartha Ganguly, Casey Williams, Omar S. Aljitawi, Ruben Reyes, Suman Kambhampati, Kapil N. Bhalla
Publikováno v:
Blood. 118:3610-3610
Abstract 3610 The activated FMS-like tyrosine kinase 3 (FLT3) receptor promotes proliferation, survival and differentiation of primitive hematopoietic progenitor cells, with downstream targets including the Raf/MEK/ERK pathway. Methylation-associated
Autor:
Joseph P. McGuirk, Siddhartha Ganguly, Lauren E. Damon, Ruben Reyes, Jacqueline E. Smith, Kapil N. Bhalla, Elisabeth A. Lasater, Mark S. Berger, Allan Fleming, Scott C. Wise, Sara Salerno, Catherine C. Smith, Warren Fiskus, Neil P. Shah, Tom J. Rutkoski
Publikováno v:
Blood. 118:2611-2611
Abstract 2611 Approximately 30% of acute myeloid leukemia (AML) patients have activating mutations in FLT3, commonly internal tandem duplication (ITD) mutations, which are associated with poor survival. Although FLT3 tyrosine kinase inhibitors (TKI)
Autor:
Livers, Allan Fleming
Publikováno v:
Dissertations, Theses, and Masters Projects.