Proteomic profiling reveals diagnostic signatures and pathogenic insights in multisystem inflammatory syndrome in children

Autor: Ulrikka Nygaard, Annelaura Bach Nielsen, Kia Hee Schultz Dungu, Lylia Drici, Mette Holm, Maud Eline Ottenheijm, Allan Bybeck Nielsen, Jonathan Peter Glenthøj, Lisbeth Samsø Schmidt, Dina Cortes, Inger Merete Jørgensen, Trine Hyrup Mogensen, Kjeld Schmiegelow, Matthias Mann, Nadja Hawwa Vissing, Nicolai J. Wewer Albrechtsen

Publikováno v: Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)

Abstract Multisystem inflammatory syndrome in children (MIS-C) is a severe disease that emerged during the COVID-19 pandemic. Although recognized as an immune-mediated condition, the pathogenesis remains unresolved. Furthermore, the absence of a diag

Externí odkaz: https://doaj.org/article/48a8c9538a9045699b5e329e6d316bf2

Multisystem inflammatory syndrome in children occurred in one of four thousand children with severe acute respiratory syndrome coronavirus-2

Autor: Morten Søndergaard Lindhard, Maren Johanne Heilskov Rytter, Alexandra Yasmin Kruse, Allan Bybeck Nielsen, Jens Jakob Herrche Petersen, Jesper Thaarup, Grethe Lemvik, Lise Jensen, Marie Cecilie Lawaetz, Pawel Andrej Marcinski, Luise Borch, Tatjana Zaharov, Jonathan Peter Glenthøj, Nadja Hawwa Vissing, Ulrikka Nygaard, Lisbeth Samsø Schmidt, Kjeld Schmiegelow, Mette Holm, Ulla Birgitte Hartling, Rikke Møller Andersen

Publikováno v: Holm, M, Hartling, U B, Schmidt, L S, Glenthøj, J P, Kruse, A, Rytter, M J H, Lindhard, M S, Lawaetz, M C, Zaharov, T, Petersen, J J H, Andersen, R M, Lemvik, G, Marcinski, P, Thaarup, J, Jensen, L H, Borch, L, Nielsen, A B, Vissing, N H, Schmiegelow, K & Nygaard, U 2021, ' Multisystem inflammatory syndrome in children occurred in one of four thousand children with severe acute respiratory syndrome coronavirus-2 ', Acta Paediatrica, vol. 110, no. 9, pp. 2581-2583 . https://doi.org/10.1111/apa.15985
Holm, M, Hartling, U B, Schmidt, L S, Glenthøj, J P, Kruse, A, Rytter, M H, Lindhard, M S, Lawaetz, M C, Zaharov, T, Petersen, J J, Andersen, R M, Lemvik, G, Marcinski, P, Thaarup, J, Jensen, L H, Borch, L, Nielsen, A B, Vissing, N H, Schmiegelow, K & Nygaard, U 2021, ' Multisystem inflammatory syndrome in children occurred in one of four thousand children with severe acute respiratory syndrome coronavirus 2 ', Acta Paediatrica, vol. 110, no. 9, pp. 2581-2583 . https://doi.org/10.1111/apa.15985
Acta Paediatrica (Oslo, Norway : 1992)
Holm, M, Hartling, U B, Schmidt, L S, Glenthøj, J P, Kruse, A, Rytter, M H, Lindhard, M S, Lawaetz, M C, Zaharov, T, Petersen, J J, Andersen, R M, Lemvik, G, Marcinski, P, Thaarup, J, Jensen, L H, Borch, L, Nielsen, A B, Vissing, N H, Schmiegelow, K & Nygaard, U 2021, ' Multisystem inflammatory syndrome in children occurred in one of four thousand children with severe acute respiratory syndrome coronavirus 2 ', Acta Paediatrica, International Journal of Paediatrics, vol. 110, no. 9, pp. 2581-2583 . https://doi.org/10.1111/apa.15985

Multisystem inflammatory syndrome in children (MIS-C) is a novel disease that is associated with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).1 Until now, only one study has attempted to estimate the incidence of MIS-C among SARS-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9b12c5a2dc99386d9a599937970f79
https://pure.au.dk/portal/da/publications/multisystem-inflammatory-syndrome-in-children-occurred-in-one-of-four-thousand-children-with-severe-acute-respiratory-syndrome-coronavirus2(4f29dc2c-d66e-460f-b76b-1ed5a03ae69c).html

Immunity to vaccine-preventable diseases among paediatric healthcare workers in Denmark, 2019

Autor: Marie-Louise von Linstow, Didi Bang, Nikolai Kirkby, Alex C. Y. Nielsen, Anja Poulsen, Thilde Nordmann Winther, Anna Korsgaard Eltvedt, Allan Bybeck Nielsen

Publikováno v: Eurosurveillance

Background Healthcare workers (HCW) have been identified as index cases in disease outbreaks of vaccine-preventable diseases (VPD) in hospitals. Aim We investigated whether Danish paediatric HCW were protected against selected serious VPD. Methods We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98337b1ea10653a5d98d903e4d5a7a78
https://doi.org/10.2807/1560-7917.es.2021.26.17.2001167

Short individualised treatment of bone and joint infections in Danish children

Autor: Kim Kristensen, Thomas Hoffmann, Ulrikka Nygaard, Allan Bybeck Nielsen

Publikováno v: Archives of Disease in Childhood. 104:205-206

Short individualised treatment of paediatric bone and joint infections, based on clinical and laboratory response, has the potential to reduce the duration of antibiotic therapy, but only few data exist on this treatment.1–4 In Denmark, short indiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ae053b80a4854b98c0e81b4a100fa2
https://doi.org/10.1136/archdischild-2018-315734

Immune response after one or two doses of pandemic influenza A (H1N1) monovalent, AS03-adjuvanted vaccine in HIV infected adults

Autor: Gitte Kronborg, Henriette Schjønning Nielsen, Lars Nielsen, Søren Thybo, Allan Bybeck Nielsen

Publikováno v: Vaccine. 30(49)

Introduction Continued research is needed to evaluate and improve the immunogenicity of influenza vaccines in HIV infected patients. We aimed to determine the antibody responses after one or two doses of the AS03-adjuvanted pandemic influenza A (H1N1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da1bbf77cad87f53f43732a70d53414
https://pubmed.ncbi.nlm.nih.gov/23036498