Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alla V Klyuyeva"'
Autor:
Olga V Belyaeva, Alla V Klyuyeva, Ansh Vyas, Wilhelm K Berger, Laszlo Halasz, Jianshi Yu, Venkatram R Atigadda, Aja Slay, Kelli R Goggans, Matthew B Renfrow, Maureen A Kane, Laszlo Nagy, Natalia Y Kedishvili
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301447 (2024)
Rexinoids are agonists of nuclear rexinoid X receptors (RXR) that heterodimerize with other nuclear receptors to regulate gene transcription. A number of selective RXR agonists have been developed for clinical use but their application has been hampe
Externí odkaz:
https://doaj.org/article/6e5107cea5b448e6b9fa7b3d56162106
Autor:
Jianfeng Li, Silvia Garavaglia, Zhaofeng Ye, Andrea Moretti, Olga V. Belyaeva, Alison Beiser, Md Ibrahim, Anna Wilk, Steve McClellan, Alla V. Klyuyeva, Kelli R. Goggans, Natalia Y. Kedishvili, E. Alan Salter, Andrzej Wierzbicki, Marie E. Migaud, Steven J. Mullett, Nathan A. Yates, Carlos J. Camacho, Menico Rizzi, Robert W. Sobol
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Using in silico modeling, Li et al. identify a selective inhibitor for aldehyde dehydrogenase isoform ALDH1A3, which is highly expressed in mesenchymal glioma stem cells and therefore a potential drug target. They solve the structure of the ALDH1A3/M
Externí odkaz:
https://doaj.org/article/d4ab4bd6ea5d4fe5ac3e294cb177d517
Autor:
Nathalia Melo, Olga V. Belyaeva, Wilhelm K. Berger, Laszlo Halasz, Jianshi Yu, Nagesh Pilli, Zhengrong Yang, Alla V. Klyuyeva, Craig A. Elmets, Venkatram Atigadda, Donald D. Muccio, Maureen A. Kane, Laszlo Nagy, Natalia Y. Kedishvili, Matthew B. Renfrow
Publikováno v:
The Journal of biological chemistry.
Retinoid X receptors (RXR) are nuclear transcription factors that partner with other nuclear receptors to regulate numerous physiological processes. Although RXR represents a valid therapeutic target, only a few RXR-specific ligands (rexinoids) have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca43ef40e3965ebb1235dd43253ddada
https://pubmed.ncbi.nlm.nih.gov/36436565
https://pubmed.ncbi.nlm.nih.gov/36436565
Publikováno v:
Methods in enzymology. 637
Several human enzymes of the short-chain dehydrogenase/reductase (SDR) superfamily of proteins exhibit catalytic oxidoreductive activity toward retinoid substrates in vitro. For some retinoid-active enzymes, their physiological significance for retin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5c9e629379bfbea05357c8da77d800d
https://pubmed.ncbi.nlm.nih.gov/32359656
https://pubmed.ncbi.nlm.nih.gov/32359656
Autor:
Kelli R. Goggans, Olga V. Belyaeva, Alla V. Klyuyeva, Jacob Studdard, Aja Slay, Regina B. Newman, Christine A. VanBuren, Helen B. Everts, Natalia Y. Kedishvili
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract The hair follicle (HF) is a self-renewing adult miniorgan that undergoes drastic metabolic and morphological changes during precisely timed cyclic organogenesis. The HF cycle is known to be regulated by steroid hormones, growth factors and c
Externí odkaz:
https://doaj.org/article/178a885c5b3041828802ae186182adf6