Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer

Autor: Andrea Strakova, Thomas J. Nicholls, Adrian Baez-Ortega, Máire Ní Leathlobhair, Alexander T. Sampson, Katherine Hughes, Isobelle A. G. Bolton, Kevin Gori, Jinhong Wang, Ilona Airikkala-Otter, Janice L. Allen, Karen M. Allum, Clara L. Arnold, Leontine Bansse-Issa, Thinlay N. Bhutia, Jocelyn L. Bisson, Kelli Blank, Cristóbal Briceño, Artemio Castillo Domracheva, Anne M. Corrigan, Hugh R. Cran, Jane T. Crawford, Stephen M. Cutter, Eric Davis, Karina F. de Castro, Andrigo B. De Nardi, Anna P. de Vos, Laura Delgadillo Keenan, Edward M. Donelan, Adela R. Espinoza Huerta, Ibikunle A. Faramade, Mohammed Fazil, Eleni Fotopoulou, Skye N. Fruean, Fanny Gallardo-Arrieta, Olga Glebova, Pagona G. Gouletsou, Rodrigo F. Häfelin Manrique, Joaquim J. G. P. Henriques, Rodrigo S. Horta, Natalia Ignatenko, Yaghouba Kane, Cathy King, Debbie Koenig, Ada Krupa, Steven J. Kruzeniski, Marta Lanza-Perea, Mihran Lazyan, Adriana M. Lopez Quintana, Thibault Losfelt, Gabriele Marino, Simón Martínez Castañeda, Mayra F. Martínez-López, Bedan M. Masuruli, Michael Meyer, Edward J. Migneco, Berna Nakanwagi, Karter B. Neal, Winifred Neunzig, Sally J. Nixon, Antonio Ortega-Pacheco, Francisco Pedraza-Ordoñez, Maria C. Peleteiro, Katherine Polak, Ruth J. Pye, Juan C. Ramirez-Ante, John F. Reece, Jose Rojas Gutierrez, Haleema Sadia, Sheila K. Schmeling, Olga Shamanova, Alan G. Sherlock, Audrey E. Steenland-Smit, Alla Svitich, Lester J. Tapia Martínez, Ismail Thoya Ngoka, Cristian G. Torres, Elizabeth M. Tudor, Mirjam G. van der Wel, Bogdan A. Vițălaru, Sevil A. Vural, Oliver Walkinton, Alvaro S. Wehrle-Martinez, Sophie A. E. Widdowson, Irina Zvarich, Patrick F. Chinnery, Maria Falkenberg, Claes M. Gustafsson, Elizabeth P. Murchison

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

The competitive dynamics of mitochondrial haplotypes juxtaposed within the same cell are poorly studied. Here the authors show, in the context of a transmissible cancer, that one haplotype has recurrently entered cancer cells by horizontal transfer a

Externí odkaz: https://doaj.org/article/cb9d1b65978f4b9aba741090656d7d49

Somatic evolution and global expansion of an ancient transmissible cancer lineage

Autor: Ludmil B. Alexandrov, Janice L Allen, Maximilian R Stammnitz, Adrian Baez-Ortega, Ismail Thoya Ngoka, Yaghouba Kane, Katherine Polak, Debbie Koenig, Gabriele Marino, Inigo Martincorena, Berna Nakanwagi, Andrigo Barboza De Nardi, Joaquim Henriques, Mayra F Martínez-López, Artemio Castillo Domracheva, Cathy King, Thibault Losfelt, Kevin Gori, Young Mi Kwon, Ada Krupa, John F Reece, Antonio Ortega-Pacheco, Natalia Ignatenko, Alvaro S Wehrle-Martinez, Pagona G. Gouletsou, Sally J Nixon, Bogdan A. Viţălaru, Laura Delgadillo Keenan, Elizabeth M Tudor, Audrey E Steenland-Smit, Hugh R Cran, Sevil Atalay Vural, Marta Lanza-Perea, Leontine Bansse-Issa, Michael R. Stratton, Edward J. Migneco, Maria C. Peleteiro, Karina F de Castro, Michael C. Meyer, Eric Davis, Sheila K Schmeling, Adriana M Lopez Quintana, Elizabeth P. Murchison, Simón Martínez Castañeda, Olga Shamanova, Rodrigo dos Santos Horta, Jinhong Wang, Mihran Lazyan, Fanny Gallardo-Arrieta, Skye N Fruean, Karter B. Neal, Anna P de Vos, Jocelyn L Bisson, Alan G. Sherlock, Sophie A.E. Widdowson, Olga Glebova, Lester J. Tapia Martínez, Mohammed Fazil, Steven J. Kruzeniski, Cristian G. Torres, Oliver Walkinton, Ibikunle A Faramade, Winifred Neunzig, Jose Rojas Gutierrez, Adela R. Espinoza Huerta, Mirjam G van der Wel, Haleema Sadia, Edward M Donelan, Alla Svitich, Rodrigo F Häfelin Manrique, Thinlay N Bhutia, Eleni Fotopoulou, Karen M Allum, Francisco Pedraza-Ordoñez, Cristóbal Briceño, Ruth J. Pye, Máire Ní Leathlobhair, Jane T Crawford, Andrea Strakova, Anne M Corrigan

Publikováno v: Baez-Ortega, A, Gori, K, Strakova, A, Allen, J L, Allum, K M, Bansse-Issa, L, Bhutia, T N, Bisson, J L, Briceño, C, Castillo Domracheva, A, Corrigan, A M, Cran, H R, Crawford, J T, Davis, E, de Castro, K F, B de Nardi, A, de Vos, A P, Delgadillo Keenan, L, Donelan, E M, Espinoza Huerta, A R, Faramade, I A, Fazil, M, Fotopoulou, E, Fruean, S N, Gallardo-Arrieta, F, Glebova, O, Gouletsou, P G, Häfelin Manrique, R F, Henriques, J J G P, Horta, R S, Ignatenko, N, Kane, Y, King, C, Koenig, D, Krupa, A, Kruzeniski, S J, Kwon, Y-M, Lanza-Perea, M, Lazyan, M, Lopez Quintana, A M, Losfelt, T, Marino, G, Martínez Castañeda, S, Martínez-López, M F, Meyer, M, Migneco, E J, Nakanwagi, B, Neal, K B, Neunzig, W, Ní Leathlobhair, M, Nixon, S J, Ortega-Pacheco, A, Pedraza-Ordoñez, F, Peleteiro, M C, Polak, K, Pye, R J, Reece, J F, Rojas Gutierrez, J, Sadia, H, Schmeling, S K, Shamanova, O, Sherlock, A G, Stammnitz, M, Steenland-Smit, A E, Svitich, A, Tapia Martínez, L J, Thoya Ngoka, I, Torres, C G, Tudor, E M, van der Wel, M G, Viţălaru, B A, Vural, S A, Walkinton, O, Wang, J, Wehrle-Martinez, A S, Widdowson, S A E, Stratton, M R, Alexandrov, L B, Martincorena, I & Murchison, E P 2019, ' Somatic evolution and global expansion of an ancient transmissible cancer lineage ', Science, vol. 365, no. 6452 . https://doi.org/10.1126/science.aau9923
Science (New York, N.Y.)
Science
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Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2019-10-06T15:53:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-02 GPD Charitable Trust Leverhulme Trust The canine transmissible venereal tumor (CTVT) is a cancer lineage that arose several millennia ago and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a8d470dc0d731744f9f15700e58704
https://hdl.handle.net/20.500.11820/f34b369d-63dd-4dc1-8101-e952ba9a35e9

Author response: Mitochondrial genetic diversity, selection and recombination in a canine transmissible cancer

Autor: Rodrigo F Häfelin Manrique, Richard K Ssuna, Laura Delgadillo Keenan, Alvaro S Wehrle-Martinez, Debbie Koenig, Inigo Martincorena, Anna P de Vos, Sheila K Schmeling, Sophie A.E. Widdowson, Ismail Thoya Ngoka, John F Reece, Janice L Allen, Karina F de Castro, Eleni Fotopoulou, Berna Nakanwagi, Elizabeth P. Murchison, Maria C. Peleteiro, Ilona Airikkala-Otter, Andrigo Barboza De Nardi, Erika Flores Reynoso, Thibault Losfelt, Ting-Ting Yin, Simón Martínez Castañeda, Jocelyn L Bisson, Oliver Walkinton, Michael Meyer, Haleema Sadia, Marta Lanza-Perea, Edward M Donelan, Audrey E Steenland-Smit, Leontine Bansse-Issa, Natalia Ignatenko, Antonio Ortega-Pacheco, David C. Wedge, Fanny Gallardo-Arrieta, Adriana M Lopez Quintana, Olga Glebova, Johan P de Vos, Artemio Castillo Domracheva, Bogdan A Vițălaru, Ibikunle A Faramade, Guo-Dong Wang, Gabriele Marino, Joaquim Henriques, Mirjam G van der Wel, Karen M Allum, Sally J Nixon, Alla Svitich, Ruth J. Pye, Mayra F Martínez-López, Máire Ní Leathlobhair, Jane T Crawford, Andrea Strakova, Anne M Corrigan, Hugh R Cran, Olga Shamanova, Remo Lobetti, Winifred Neunzig, Jose Rojas Gutierrez, Marsden M Onsare, Stephen M Cutter, Skye N Fruean

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc6ce2c2089810db1ee2ea15dc36b7a9
https://doi.org/10.7554/elife.14552.034