Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Alla Slynko"'
Autor:
Marieke Stolte, Nicholas Schreck, Alla Slynko, Maral Saadati, Axel Benner, Jörg Rahnenführer, Andrea Bommert
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0299989 (2024)
Simulation is a crucial tool for the evaluation and comparison of statistical methods. How to design fair and neutral simulation studies is therefore of great interest for both researchers developing new methods and practitioners confronted with the
Externí odkaz:
https://doaj.org/article/e231b4d5b6014a938d68a234ba7635bd
Autor:
Marco R. Cosenza, Anna Cazzola, Annik Rossberg, Nicole L. Schieber, Gleb Konotop, Elena Bausch, Alla Slynko, Tim Holland-Letz, Marc S. Raab, Taronish Dubash, Hanno Glimm, Sven Poppelreuther, Christel Herold-Mende, Yannick Schwab, Alwin Krämer
Publikováno v:
Cell Reports, Vol 20, Iss 8, Pp 1906-1920 (2017)
Chromosomal instability is a hallmark of cancer and correlates with the presence of extra centrosomes, which originate from centriole overduplication. Overduplicated centrioles lead to the formation of centriole rosettes, which mature into supernumer
Externí odkaz:
https://doaj.org/article/193775385eee40bca446c8e132ca6f3b
Autor:
Stefan Alexander Koerber, Erik Winter, Sonja Katayama, Alla Slynko, Matthias Felix Haefner, Matthias Uhl, Florian Sterzing, Gregor Habl, Kai Schubert, Juergen Debus, Klaus Herfarth
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Introduction: This prospective, non-randomized phase II trial aimed to investigate the role of additional irradiation of the pelvic nodes for patients with prostate cancer and a high risk for nodal metastases using helical intensity-modulated radioth
Externí odkaz:
https://doaj.org/article/af7c19db2cac4b658062d231529b7946
Autor:
Alla Slynko, Axel Benner
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218103 (2019)
Hydroxymethylcytosine (5hmC) methylation is a well-known epigenetic mark that is involved in gene regulation and may impact genome stability. To investigate a possible role of 5hmC in cancer development and progression, one must be able to detect and
Externí odkaz:
https://doaj.org/article/0da7ec62045443bb80654349c8db305f
Autor:
Christoph Weigel, Marlon R. Veldwijk, Christopher C. Oakes, Petra Seibold, Alla Slynko, David B. Liesenfeld, Mariona Rabionet, Sabrina A. Hanke, Frederik Wenz, Elena Sperk, Axel Benner, Christoph Rösli, Roger Sandhoff, Yassen Assenov, Christoph Plass, Carsten Herskind, Jenny Chang-Claude, Peter Schmezer, Odilia Popanda
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Radiotherapy can induce fibrosis in cancer patients, limiting its use in clinical settings. Here, the authors identify a differentially methylated enhancer of the lipid kinase DGKA in fibroblasts from breast cancer patients developing fibrosis after
Externí odkaz:
https://doaj.org/article/8d2cbcdc585d437387a5d8eedf91802c
Autor:
Alla Slynko
Publikováno v:
Statistical Papers (Berlin, Germany)
To access the reliability of a new dichotomous test and to capture the random variability of its results in the absence of a gold standard, two measures, the inconsistent acceptance probability (IAP) and inconsistent rejection probability (IRP), were
Autor:
Nina Lang, Alexander Enk, Jessica C. Hassel, Christos Sachpekidis, Carsten Schulz, Julika Dick, Alla Slynko, Antonia Dimitrakopoulou-Strauss
Publikováno v:
Immunotherapy. 11:667-676
Aim: Autoimmune colitis is a typical and possible severe side effect among patients treated with ipilimumab. Patients & methods: We prospectively included 100 patients with metastasized melanoma under ipilimumab treatment in a radiological study of 1
Autor:
Alla Slynko
Publikováno v:
Mathematical Biosciences. 343:108729
In this paper we address the situation where a well-established, but invasive, expensive or time-consuming diagnostic test may be replaced by multiple repetitions of a different diagnostic test which is known to be imperfect but less invasive or expe
Autor:
Ado, Alla Slynko, Ralf Gutzmer, Carolin Bender, Lisa Zimmer, Selma Ugurel, Benjamin Weide, Kristina Buder-Bakhaya, Carmen Loquai, Jessica C. Hassel
Publikováno v:
Cancer Medicine
Despite markedly improved treatment options for metastatic melanoma, resistance to targeted therapies such as BRAF inhibitors (BRAFi) or BRAFi plus MEK inhibitors (MEKi) remains a major problem. Our aim was to characterize progression on BRAFi therap
Autor:
Yannick Schwab, Marco R. Cosenza, Annik Rossberg, Taronish D. Dubash, Alla Slynko, Gleb Konotop, Hanno Glimm, Elena Bausch, Christel Herold-Mende, Alwin Krämer, Marc S. Raab, Tim Holland-Letz, Sven Poppelreuther, Nicole L. Schieber, Anna Cazzola
Publikováno v:
Cell Reports, Vol 20, Iss 8, Pp 1906-1920 (2017)
Chromosomal instability is a hallmark of cancer and correlates with the presence of extra centrosomes, which originate from centriole overduplication. Overduplicated centrioles lead to the formation of centriole rosettes, which mature into supernumer