Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alla Romashko"'
Autor:
Andrea Iskenderian, Nan Liu, Qingwei Deng, Yan Huang, Chuan Shen, Kathleen Palmieri, Robert Crooker, Dianna Lundberg, Niksa Kastrapeli, Brian Pescatore, Alla Romashko, John Dumas, Robert Comeau, Angela Norton, Jing Pan, Haojing Rong, Katayoun Derakhchan, David E. Ehmann
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract Background Myostatin antagonists are being developed as therapies for Duchenne muscular dystrophy due to their strong hypertrophic effects on skeletal muscle. Engineered follistatin has the potential to combine the hypertrophy of myostatin a
Externí odkaz:
https://doaj.org/article/67bfaa2651914f7787073ccc6974c8c1
Publikováno v:
Theory and Practice of Intellectual Property. :74-84
Keywords: innovations, innovation management, intellectual property, managementsystems, management system standards The UN General Assembly Resolution dated September 25,2015 set goals for sustainable development, which are actively accepted around t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ded427327cbdbc0303ccf8002c7523f9
https://doi.org/10.33731/22022.259746
https://doi.org/10.33731/22022.259746
Publikováno v:
Theory and Practice of Intellectual Property. :34-44
Keywords: scientific and technical information, intellectual property, trade secret,invention, utility model, rationalization proposal, WIPO PROOF, management system The article is devoted to defining terms for information inorder to use it effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03a6358dd8c4a78afcdfffb7f816f91d
https://doi.org/10.33731/32021.239581
https://doi.org/10.33731/32021.239581
Autor:
Devin Welty, Alla Romashko, Serene Josiah, Steve Van Adestine, Chulbul M. Ahmed, Anneli Savinainen, Alfred S. Lewin, Brian Dwyer, Zhen Lou, Bohong Zhang, Eun-Hee Park
Publikováno v:
Translational Vision Science & Technology
Purpose Mutations in RHO, the gene for a rhodopsin, are a leading cause of autosomal dominant retinitis pigmentosa. The objective of this study was to determine if a synthetic retinal analogue (SRD005825) serves as a pharmacologic chaperone to promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2777ba016a5ea108e126b32d2d219f
http://europepmc.org/articles/PMC6910612
http://europepmc.org/articles/PMC6910612
Autor:
Kathleen Palmieri, Bohong Zhang, Muthuraman Meiyappan, Sheng Gu, Matthew Traylor, Brian Pescatore, Robert Crooker, Angela W. Norton, David E. Ehmann, Clark Pan, Dianna Lundberg, George Baviello, Chuan Shen, Qingwei Deng, Bettina Strack-Logue, Alla Romashko, Tao He, Andrea Iskenderian, Haojing Rong, John Gill
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 366:291-302
Follistatin (FS) is an important regulatory protein, a natural antagonist for transforming growth factor-β family members activin and myostatin. The diverse biologic roles of the activin and myostatin signaling pathways make FS a promising therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31d0c29b0ec54cf1d6e1bd8246deac9
https://doi.org/10.1124/jpet.118.248195
https://doi.org/10.1124/jpet.118.248195
Autor:
Holmes Kevin, Muthuraman Meiyappan, Michael F. Concino, Alla Romashko, Bohong Zhang, Angela W. Norton, Dianna Lundberg, Thomas Cottle, Anne-Laure Dassier, Gabriel Birrane
Publikováno v:
Journal of structural biology. 205(3)
Mucopolysaccharidosis III B (MPS III-B) is a rare lysosomal storage disorder caused by deficiencies in Alpha-N-acetylglucosaminidase (NAGLU) for which there is currently no cure, and present treatment is largely supportive. Understanding the structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1dd713abeaac8735e704a0d7dec80c
https://pubmed.ncbi.nlm.nih.gov/30802506
https://pubmed.ncbi.nlm.nih.gov/30802506
Autor:
Jing Pan, Alla Romashko, David E. Ehmann, Katayoun Derakhchan, Angela W. Norton, Andrea Iskenderian, Qingwei Deng, Robert Comeau, Robert Crooker, Nan Liu, John Dumas, Chuan Shen, Niksa Kastrapeli, Dianna Lundberg, Brian Pescatore, Kathleen Palmieri, Haojing Rong, Yan Huang
Publikováno v:
Skeletal Muscle
Skeletal Muscle, Vol 8, Iss 1, Pp 1-16 (2018)
Skeletal Muscle, Vol 8, Iss 1, Pp 1-16 (2018)
Background Myostatin antagonists are being developed as therapies for Duchenne muscular dystrophy due to their strong hypertrophic effects on skeletal muscle. Engineered follistatin has the potential to combine the hypertrophy of myostatin antagonism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2104cea901b16f8803bff66aa10bb0
https://pubmed.ncbi.nlm.nih.gov/30368252
https://pubmed.ncbi.nlm.nih.gov/30368252
Autor:
Lynette C. Cook, Michael A. Jones, Angela W. Norton, Paolo Martini, Sarah M. Peterson, Michael W. Heartlein, Michael F. Concino, Andrea Iskenderian, Alla Romashko, Kristen Tobin, Alicia Gómez-Yafal, Lucy Liaw
Publikováno v:
BMC Cancer
BMC Cancer, Vol 10, Iss 1, p 427 (2010)
BMC Cancer, Vol 10, Iss 1, p 427 (2010)
Background Extracellular human sulfatases modulate growth factor signaling by alteration of the heparin/heparan sulfate proteoglycan (HSPG) 6-O-sulfation state. HSPGs bind to numerous growth factor ligands including fibroblast growth factors (FGF), e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7c34c7e30eb2f83ef223a9a21f65e6
https://doi.org/10.1186/1471-2407-10-427
https://doi.org/10.1186/1471-2407-10-427
Overexpression of the RNA polymerase alpha subunit in Bordetella pertussis reduces expression of the virulence factor pertussis toxin. Here we show that this reduction is at the level of transcription, is reversed by overexpression of the transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab6287ba5a1ca25e461bf3bc07450f3
https://europepmc.org/articles/PMC94308/
https://europepmc.org/articles/PMC94308/
Autor:
Gregory Grabowski, Hong Du, Brian Pescatore, Alla Romashko, Muthu Meiyappan, Paolo Martini, Lawrence Charnas, Alicia Gomez-Yafal, You-Hai Xu, Oluwaseyi Westmoreland, Lori Stanton
Publikováno v:
Molecular Genetics and Metabolism. 102:S19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c546eaa31436feccf47832ced34c22e
https://doi.org/10.1016/j.ymgme.2010.11.065
https://doi.org/10.1016/j.ymgme.2010.11.065