Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alla Peselis"'
Publikováno v:
Cell Reports, Vol 13, Iss 9, Pp 1800-1813 (2015)
Naturally occurring L-glutamine riboswitches occur in cyanobacteria and marine metagenomes, where they reside upstream of genes involved in nitrogen metabolism. By combining X-ray, NMR, and MD, we characterized an L-glutamine-dependent conformational
Externí odkaz:
https://doaj.org/article/df398b46981d438f97410eb57137cd6d
Autor:
Peter O. Fedichev, Ashok Nuthanakanti, Evgeny Nudler, Alexander Mironov, Dmitry Shishov, Ilya Shamovsky, Mirna Lechpammer, Nikita Vasilyev, Elena Shatalina, Konstantin Shatalin, Dmitri Rebatchouk, Abhishek Kaushik, Alla Peselis, Bibhusita Pani, Alexander Serganov
Publikováno v:
Science. 372:1169-1175
Turning down tolerance Persister cells, which are found in abundance in biofilms, adopt a quiescent state and survive antimicrobial treatments, seeding disease recurrence and incubating new resistance mutations. Building on work implicating the react
Autor:
Alexander Serganov, Alla Peselis
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611531
Allostery is among the most basic biological principles employed by biological macromolecules to achieve a biologically active state in response to chemical cues. Although initially used to describe the impact of small molecules on the conformation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f3c76aea289f8ce776462a42c170fc0
https://doi.org/10.1007/978-1-0716-1154-8_15
https://doi.org/10.1007/978-1-0716-1154-8_15
Autor:
Alla, Peselis, Alexander, Serganov
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2253
Allostery is among the most basic biological principles employed by biological macromolecules to achieve a biologically active state in response to chemical cues. Although initially used to describe the impact of small molecules on the conformation a
Autor:
Konstantin, Shatalin, Ashok, Nuthanakanti, Abhishek, Kaushik, Dmitry, Shishov, Alla, Peselis, Ilya, Shamovsky, Bibhusita, Pani, Mirna, Lechpammer, Nikita, Vasilyev, Elena, Shatalina, Dmitri, Rebatchouk, Alexander, Mironov, Peter, Fedichev, Alexander, Serganov, Evgeny, Nudler
Publikováno v:
Science (New York, N.Y.). 372(6547)
Emergent resistance to all clinical antibiotics calls for the next generation of therapeutics. Here we report an effective antimicrobial strategy targeting the bacterial hydrogen sulfide (H
Autor:
Alla Peselis, Alexander Serganov
Publikováno v:
Nature chemical biology
The ykkC family of bacterial riboswitches combines several widespread classes that have similar secondary structures and consensus motifs but control different genes in response to different cellular metabolites. Here we report the crystal structures
Publikováno v:
Cell Reports, Vol 13, Iss 9, Pp 1800-1813 (2015)
SummaryNaturally occurring L-glutamine riboswitches occur in cyanobacteria and marine metagenomes, where they reside upstream of genes involved in nitrogen metabolism. By combining X-ray, NMR, and MD, we characterized an L-glutamine-dependent conform
Autor:
Alexander Serganov, Alla Peselis
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1839:908-918
The complexity of gene expression control by non-coding RNA has been highlighted by the recent progress in the field of riboswitches. Discovered a decade ago, riboswitches represent a diverse group of non-coding mRNA regions that possess a unique abi
Autor:
Alexander Serganov, Alla Peselis
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 5:803-822
Natural RNA molecules can have a high degree of structural complexity but even the most complexly folded RNAs are assembled from simple structural building blocks. Among the simplest RNA elements are double-stranded helices that participate in the fo
Publikováno v:
Methods in Molecular Biology ISBN: 9781493927623
Recent studies have revealed that the majority of biological processes are controlled by noncoding RNAs. Among many classes of noncoding RNAs, metabolite-sensing segments of mRNAs called riboswitches are unique. Discovered over a decade ago in all th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a150b8f8ae777eb651e901149ae8058c
https://doi.org/10.1007/978-1-4939-2763-0_3
https://doi.org/10.1007/978-1-4939-2763-0_3