Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Alla Gagarinova"'
Autor:
Alla Gagarinova, Ali Hosseinnia, Matineh Rahmatbakhsh, Zoe Istace, Sadhna Phanse, Mohamed Taha Moutaoufik, Mara Zilocchi, Qingzhou Zhang, Hiroyuki Aoki, Matthew Jessulat, Sunyoung Kim, Khaled A. Aly, Mohan Babu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The bacterium E. coli has around 300 transcriptional factors, but the functions of many of them, and the interactions between their respective regulatory networks, are unclear. Here, the authors study genetic interactions among all transcription fact
Externí odkaz:
https://doaj.org/article/e26b507a74f145268dd8fb6fa76b67a2
Autor:
Bálint Kintses, Pramod K. Jangir, Gergely Fekete, Mónika Számel, Orsolya Méhi, Réka Spohn, Lejla Daruka, Ana Martins, Ali Hosseinnia, Alla Gagarinova, Sunyoung Kim, Sadhna Phanse, Bálint Csörgő, Ádám Györkei, Eszter Ari, Viktória Lázár, István Nagy, Mohan Babu, Csaba Pál, Balázs Papp
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The genetics underlying bacterial susceptibility to antimicrobial peptides (AMPs) remain unclear. Here, using a genome-wide chemical-genetic approach, the authors map the diversity of resistance determinants across AMPs in Escherichia coli and provid
Externí odkaz:
https://doaj.org/article/e0586b491c9a457fa943b36f2a4c75e9
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Microbial pathogens have evolved numerous mechanisms to hijack host’s systems, thus causing disease. This is mediated by alterations in the combined host-pathogen proteome in time and space. Mass spectrometry-based proteomics approaches have been d
Externí odkaz:
https://doaj.org/article/0f828625b27f48f4afe3ede8950296f8
Autor:
Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu
Publikováno v:
iScience, Vol 19, Iss , Pp 1114-1132 (2019)
Summary: Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-ba
Externí odkaz:
https://doaj.org/article/c6301e8c20a347908830d745496bf253
Autor:
Alla Gagarinova, Geordie Stewart, Bahram Samanfar, Sadhna Phanse, Carl A. White, Hiroyuki Aoki, Viktor Deineko, Natalia Beloglazova, Alexander F. Yakunin, Ashkan Golshani, Eric D. Brown, Mohan Babu, Andrew Emili
Publikováno v:
Cell Reports, Vol 17, Iss 3, Pp 904-916 (2016)
Bacterial protein synthesis is an essential, conserved, and environmentally responsive process. Yet, many of its components and dependencies remain unidentified. To address this gap, we used quantitative synthetic genetic arrays to map functional rel
Externí odkaz:
https://doaj.org/article/dac41ea360a046c5a5f5850ed06d8be2
Autor:
Ednalise Santiago, Pearl Akamine, Jamie Snider, Victoria Wong, Matthew Jessulat, Viktor Deineko, Alla Gagarinova, Hiroyuki Aoki, Zoran Minic, Sadhna Phanse, Andrea San Antonio, Luis A. Cubano, Brian C. Rymond, Mohan Babu, Igor Stagljar, Jose R. Rodriguez-Medina
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 5, Pp 1469-1474 (2016)
Nonmuscle myosin type II (Myo1p) is required for cytokinesis in the budding yeast Saccharomyces cerevisiae. Loss of Myo1p activity has been associated with growth abnormalities and enhanced sensitivity to osmotic stress, making it an appealing antifu
Externí odkaz:
https://doaj.org/article/57d4a251d67b42f4ab2e949e60cb2267
Autor:
Ashwani Kumar, Natalia Beloglazova, Cedoljub Bundalovic-Torma, Sadhna Phanse, Viktor Deineko, Alla Gagarinova, Gabriel Musso, James Vlasblom, Sofia Lemak, Mohsen Hooshyar, Zoran Minic, Omar Wagih, Roberto Mosca, Patrick Aloy, Ashkan Golshani, John Parkinson, Andrew Emili, Alexander F. Yakunin, Mohan Babu
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 648-661 (2016)
As antibiotic resistance is increasingly becoming a public health concern, an improved understanding of the bacterial DNA damage response (DDR), which is commonly targeted by antibiotics, could be of tremendous therapeutic value. Although the genetic
Externí odkaz:
https://doaj.org/article/9fbd82c0796d4664a9c936ea2215594d
Autor:
Mohan Babu, Roland Arnold, Cedoljub Bundalovic-Torma, Alla Gagarinova, Keith S Wong, Ashwani Kumar, Geordie Stewart, Bahram Samanfar, Hiroyuki Aoki, Omar Wagih, James Vlasblom, Sadhna Phanse, Krunal Lad, Angela Yeou Hsiung Yu, Christopher Graham, Ke Jin, Eric Brown, Ashkan Golshani, Philip Kim, Gabriel Moreno-Hagelsieb, Jack Greenblatt, Walid A Houry, John Parkinson, Andrew Emili
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004120 (2014)
Large-scale proteomic analyses in Escherichia coli have documented the composition and physical relationships of multiprotein complexes, but not their functional organization into biological pathways and processes. Conversely, genetic interaction (GI
Externí odkaz:
https://doaj.org/article/2896e8427bcd49608cc1b53f2c8d503b
Autor:
Mohan Babu, J Javier Díaz-Mejía, James Vlasblom, Alla Gagarinova, Sadhna Phanse, Chris Graham, Fouad Yousif, Huiming Ding, Xuejian Xiong, Anaies Nazarians-Armavil, Md Alamgir, Mehrab Ali, Oxana Pogoutse, Asaf Pe'er, Roland Arnold, Magali Michaut, John Parkinson, Ashkan Golshani, Chris Whitfield, Shoshana J Wodak, Gabriel Moreno-Hagelsieb, Jack F Greenblatt, Andrew Emili
Publikováno v:
PLoS Genetics, Vol 7, Iss 11, p e1002377 (2011)
As the interface between a microbe and its environment, the bacterial cell envelope has broad biological and clinical significance. While numerous biosynthesis genes and pathways have been identified and studied in isolation, how these intersect func
Externí odkaz:
https://doaj.org/article/267b6741cba6464c9b09fc1d98cbfecc
Autor:
Mohan Babu, Hiroyuki Aoki, Wasimul Q Chowdhury, Alla Gagarinova, Chris Graham, Sadhna Phanse, Ben Laliberte, Noor Sunba, Matthew Jessulat, Ashkan Golshani, Andrew Emili, Jack F Greenblatt, M Clelia Ganoza
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18510 (2011)
Elongation factor RbbA is required for ATP-dependent deacyl-tRNA release presumably after each peptide bond formation; however, there is no information about the cellular role. Proteomic analysis in Escherichia coli revealed that RbbA reciprocally co
Externí odkaz:
https://doaj.org/article/17514a7b656746b6b4282c075d3f8fc5