Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alla Belko"'
Autor:
Elena Kalinichenko, Aliaksandr Faryna, Viktoria Kondrateva, Alena Vlasova, Valentina Shevchenko, Alla Melnik, Olga Avdoshko, Alla Belko
Publikováno v:
Molecules, Vol 24, Iss 19, p 3543 (2019)
A number of new compounds containing the 4-(aminomethyl)benzamide fragment as a linker were designed and synthesized, and their biological activities were evaluated as potential anticancer agents. The cytotoxicity activity of the designed compounds w
Externí odkaz:
https://doaj.org/article/148f4dfd874a4c9ba2cf819ece4d20a5
Autor:
Aliaksandr Faryna, Alla Belko, Elena N. Kalinichenko, Olga Avdoshko, Alena Vlasova, Shevchenko Valentina A, Melnik Alla K, Viktoria Kondrateva
Publikováno v:
Molecules
Volume 24
Issue 19
Molecules, Vol 24, Iss 19, p 3543 (2019)
Volume 24
Issue 19
Molecules, Vol 24, Iss 19, p 3543 (2019)
A number of new compounds containing the 4-(aminomethyl)benzamide fragment as a linker were designed and synthesized, and their biological activities were evaluated as potential anticancer agents. The cytotoxicity activity of the designed compounds w
Publikováno v:
Journal of Drug Design and Medicinal Chemistry. 3:27
Several novel imatinib structure analogues were synthesized. Antiproliferative activity testing on various leukemic cell lines showed 1-2 fold less activity against K562 cells compared to imatinib. Autodock Vina’s docking studies predicted no diffe