Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Alla Amcheslavsky"'
Autor:
Luchi Farrell, Aleix Puig-Barbe, Md Iqramul Haque, Alla Amcheslavsky, Mengyuan Yu, Andreas Bergmann, Yun Fan
Publikováno v:
PLoS Genetics, Vol 18, Iss 12, p e1010533 (2022)
Stress-induced cell death, mainly apoptosis, and its subsequent tissue repair is interlinked although our knowledge of this connection is still very limited. An intriguing finding is apoptosis-induced proliferation (AiP), an evolutionary conserved me
Externí odkaz:
https://doaj.org/article/5d58febe2ca74dea8448f8e409a49780
Autor:
Qi Li, Fiachra Humphries, Roxie C. Girardin, Aaron Wallace, Monir Ejemel, Alla Amcheslavsky, Conor T. McMahon, Zachary A. Schiller, Zepei Ma, John Cruz, Alan P. Dupuis, Anne F. Payne, Arooma Maryam, Nese Kurt Yilmaz, Kathleen A. McDonough, Brian G. Pierce, Celia A. Schiffer, Andrew C. Kruse, Mark S. Klempner, Lisa A. Cavacini, Katherine A. Fitzgerald, Yang Wang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Anti-COVID antibody therapeutics have been developed but not widely used due to their high cost and escape of neutralization from the emerging variants. Here, we describe the development of VHH-IgA1.1, a nanobody IgA fusion molecule as an inhalable,
Externí odkaz:
https://doaj.org/article/daf01ec763884ddfa115d5def03c2186
Autor:
Alla Amcheslavsky, Aaron L. Wallace, Monir Ejemel, Qi Li, Conor T. McMahon, Matteo Stoppato, Serena Giuntini, Zachary A. Schiller, Jessica R. Pondish, Jacqueline R. Toomey, Ryan M. Schneider, Jordan Meisinger, Raimond Heukers, Andrew C. Kruse, Eileen M. Barry, Brian G. Pierce, Mark S. Klempner, Lisa A. Cavacini, Yang Wang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Enterotoxigenic Escherichia coli (ETEC) is estimated to cause approximately 380,000 deaths annually during sporadic or epidemic outbreaks worldwide. Development of vaccines against ETEC is very challenging due to the vast heterogeneity of th
Externí odkaz:
https://doaj.org/article/8c71423749de4016b747f5338a446935
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The initiator caspase Dronc is the only CARD-domain containing caspase in Drosophila and is essential for apoptosis. Here, we report that homozygous dronc mutant adult animals are short-lived due to the presence of a poorly developed, defect
Externí odkaz:
https://doaj.org/article/1e7b8635b7c346bc9c000cad7a5eb057
Autor:
Alicia Shields, Alla Amcheslavsky, Elizabeth Brown, Tom V. Lee, Yingchao Nie, Takahiro Tanji, Y. Tony Ip, Andreas Bergmann
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110817- (2022)
Summary: Drosophila Toll-1 and all mammalian Toll-like receptors regulate innate immunity. However, the functions of the remaining eight Toll-related proteins in Drosophila are not fully understood. Here, we show that Drosophila Toll-9 is necessary a
Externí odkaz:
https://doaj.org/article/6a1fc7ad54e6466c9b1985c50dc6f126
Autor:
Monir Ejemel, Qi Li, Shurong Hou, Zachary A. Schiller, Julia A. Tree, Aaron Wallace, Alla Amcheslavsky, Nese Kurt Yilmaz, Karen R. Buttigieg, Michael J. Elmore, Kerry Godwin, Naomi Coombes, Jacqueline R. Toomey, Ryan Schneider, Anudeep S. Ramchetty, Brianna J. Close, Da-Yuan Chen, Hasahn L. Conway, Mohsan Saeed, Chandrashekar Ganesa, Miles W. Carroll, Lisa A. Cavacini, Mark S. Klempner, Celia A. Schiffer, Yang Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Here, Ejemel et al. report the identification and characterization of a cross-neutralizing human IgA monoclonal antibody, named MAb362, that binds the receptor-binding domain of SARS-CoV-2 Spike, blocking its interaction with the ACE2 host receptor.
Externí odkaz:
https://doaj.org/article/97644dca295e44a19fa5676282d05155
Autor:
Alla Amcheslavsky, Wei Song, Qi Li, Yingchao Nie, Ivan Bragatto, Dominique Ferrandon, Norbert Perrimon, Y. Tony Ip
Publikováno v:
Cell Reports, Vol 9, Iss 1, Pp 32-39 (2014)
Summary: Intestinal stem cells in the adult Drosophila midgut are regulated by growth factors produced from the surrounding niche cells including enterocytes and visceral muscle. The role of the other major cell type, the secretory enteroendocrine ce
Externí odkaz:
https://doaj.org/article/3c6317ccd6574b5dba070e3a1766982f
Autor:
Mark S. Klempner, Matteo Stoppato, Alla Amcheslavsky, Jessica R. Pondish, Jordan Meisinger, Monir Ejemel, Ryan Schneider, Aaron Wallace, Qi Li, Yang Wang, Jacqueline R. Toomey, Raimond Heukers, Serena Giuntini, Lisa A. Cavacini, Eileen M. Barry, Zachary A. Schiller, Conor McMahon, Brian G. Pierce, Andrew C. Kruse
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Enterotoxigenic Escherichia coli (ETEC) is estimated to cause approximately 380,000 deaths annually during sporadic or epidemic outbreaks worldwide. Development of vaccines against ETEC is very challenging due to the vast heterogeneity of the ETEC st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078cfdfd96ee937b4c593bb60c08d2bb
https://doaj.org/article/8c71423749de4016b747f5338a446935
https://doaj.org/article/8c71423749de4016b747f5338a446935
Autor:
Mark S. Klempner, Michael J. Elmore, Zachary A. Schiller, Naomi Coombes, Mohsan Saeed, Brianna J. Close, Anudeep S. Ramchetty, Kerry J Godwin, Chandrashekar Ganesa, Hasahn L. Conway, Lisa A. Cavacini, Miles W. Carroll, Julia A. Tree, Shurong Hou, Jacqueline R. Toomey, Aaron Wallace, Da Yuan Chen, Celia A. Schiffer, Karen R. Buttigieg, Monir Ejemel, Ryan Schneider, Qi Li, Yang Wang, Alla Amcheslavsky, Nese Kurt Yilmaz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
bioRxiv
Nature Communications
bioRxiv
Nature Communications
COVID-19 caused by SARS-CoV-2 has become a global pandemic requiring the development of interventions for the prevention or treatment to curtail mortality and morbidity. No vaccine to boost mucosal immunity, or as a therapeutic, has yet been develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3b0f26b99337f8cf3e2daea8e6a5e4
http://link.springer.com/article/10.1038/s41467-020-18058-8
http://link.springer.com/article/10.1038/s41467-020-18058-8
Autor:
Alicia Shields, Alla Amcheslavsky, Elizabeth Brown, Tom V. Lee, Yingchao Nie, Takahiro Tanji, Y. Tony Ip, Andreas Bergmann
Publikováno v:
Cell reports. 39(7)
Drosophila Toll-1 and all mammalian Toll-like receptors regulate innate immunity. However, the functions of the remaining eight Toll-related proteins in Drosophila are not fully understood. Here, we show that Drosophila Toll-9 is necessary and suffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d3090a16c4a382ba64c579bd38b6cb
https://pubmed.ncbi.nlm.nih.gov/35584678
https://pubmed.ncbi.nlm.nih.gov/35584678