Výsledky vyhledávání - "Alkvin Wanders"

Sentinel node lymphocytes: tumour reactive lymphocytes identified intraoperatively for the use in immunotherapy of colon cancer

Autor: Per Marits, Magnus Thörn, Ola Winqvist, Kjell Dahl, Patrik Larsson, Mona Karlsson, Alkvin Wanders

Publikováno v: British Journal of Cancer

The sentinel node is the first lymph node to receive lymphatic drainage from a tumour and is usually the first site of metastases. Today, the sentinel node is used for tumour staging. Here, we focus on its immunological role and investigate lymphocyt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4138ade5b30c1c531cec44b31f64c4a7
https://doi.org/10.1038/sj.bjc.6603126

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Assessment of normal and tumor tissue uptake of MAG-CPT, a polymer-bound prodrug of camptothecin, in patients undergoing elective surgery for colorectal carcinoma

Autor: Massimo Breda, MariaGrazia Porro, Nenad Sarapa, Haile Mahteme, Margaret R. Britto, MariaGabriella Jannuzzo, C. A. James, Alkvin Wanders, M. Rocchetti, William Speed, Peter Nygren

Publikováno v: Cancer Chemotherapy and Pharmacology. 52:424-430

MAG-camptothecin (MAG-CPT) is the lead compound of a novel drug delivery system in which an active cytotoxic moiety, camptothecin (CPT), is covalently linked to a soluble polymeric carrier (MAG) to form an inactive prodrug. The mechanism of action of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869555d99ed39176a672797a7c1787d4
https://doi.org/10.1007/s00280-003-0685-x

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