Zobrazeno 1 - 10
of 446
pro vyhledávání: '"Alkodsi, A"'
Autor:
Meriranta, Leo, Alkodsi, Amjad, Pasanen, Annika, Lepistö, Maija, Mapar, Parisa, Blaker, Yngvild Nuvin, Jørgensen, Judit, Karjalainen-Lindsberg, Marja-Liisa, Fiskvik, Idun, Mikalsen, Lars Tore G., Autio, Matias, Björkholm, Magnus, Jerkeman, Mats, Fluge, Øystein, Brown, Peter, Jyrkkiö, Sirkku, Holte, Harald, Pitkänen, Esa, Ellonen, Pekka, Leppä, Sirpa *
Publikováno v:
In Blood 24 March 2022 139(12):1863-1877
Autor:
Meriranta, Leo, Pasanen, Annika *, Alkodsi, Amjad *, Haukka, Jari, Karjalainen-Lindsberg, Marja-Liisa, Leppä, Sirpa *
Publikováno v:
In Blood Advances 11 August 2020 4(15):3742-3753
Akademický článek
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Autor:
Eevi Kaasinen, Outi Kuismin, Kristiina Rajamäki, Heikki Ristolainen, Mervi Aavikko, Johanna Kondelin, Silva Saarinen, Davide G. Berta, Riku Katainen, Elina A. M. Hirvonen, Auli Karhu, Aurora Taira, Tomas Tanskanen, Amjad Alkodsi, Minna Taipale, Ekaterina Morgunova, Kaarle Franssila, Rainer Lehtonen, Markus Mäkinen, Kristiina Aittomäki, Aarno Palotie, Mitja I. Kurki, Olli Pietiläinen, Morgane Hilpert, Elmo Saarentaus, Jaakko Niinimäki, Juhani Junttila, Kari Kaikkonen, Pia Vahteristo, Radek C. Skoda, Mikko R. J. Seppänen, Kari K. Eklund, Jussi Taipale, Outi Kilpivaara, Lauri A. Aaltonen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Somatic heterozygous TET2 loss drives clonal hematopoiesis, which is linked to malignant cell degeneration and potentially cardiovascular disease. Here, the authors investigate the molecular impact of a germline TET2 mutation in a lymphoma family, fi
Externí odkaz:
https://doaj.org/article/46989eed5d5545f397b38c9c2843f70f
Autor:
Una Kjällquist, Rikard Erlandsson, Nicholas P. Tobin, Amjad Alkodsi, Ikram Ullah, Gustav Stålhammar, Eva Karlsson, Thomas Hatschek, Johan Hartman, Sten Linnarsson, Jonas Bergh
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-17 (2018)
Abstract Background Tumor heterogeneity in breast cancer tumors is today widely recognized. Most of the available knowledge in genetic variation however, relates to the primary tumor while metastatic lesions are much less studied. Many studies have r
Externí odkaz:
https://doaj.org/article/16b1daf21e6b406297d8329ccb94c5fd
Autor:
Leo Meriranta, Amjad Alkodsi, Annika Pasanen, Maija Lepistö, Parisa Mapar, Yngvild Nuvin Blaker, Judit Jørgensen, Marja-Liisa Karjalainen-Lindsberg, Idun Fiskvik, Lars Tore G. Mikalsen, Matias Autio, Magnus Björkholm, Mats Jerkeman, Øystein Fluge, Peter Brown, Sirkku Jyrkkiö, Harald Holte, Esa Pitkänen, Pekka Ellonen, Sirpa Leppä
Publikováno v:
Blood
Meriranta, L, Alkodsi, A, Pasanen, A, Lepistö, M, Mapar, P, Blaker, Y N, Jørgensen, J M, Karjalainen-Lindsberg, M-L, Fiskvik, I, Mikalsen, L T G, Autio, M, Björkholm, M, Jerkeman, M, Fluge, Ø, Brown, P, Jyrkkiö, S, Holte, H, Pitkänen, E, Ellonen, P & Leppa, S 2022, ' Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma ', Blood, vol. 139, no. 12, pp. 1863-1877 . https://doi.org/10.1182/blood.2021012852
Meriranta, L, Alkodsi, A, Pasanen, A, Lepistö, M, Mapar, P, Blaker, Y N, Jørgensen, J M, Karjalainen-Lindsberg, M-L, Fiskvik, I, Mikalsen, L T G, Autio, M, Björkholm, M, Jerkeman, M, Fluge, Ø, Brown, P, Jyrkkiö, S, Holte, H, Pitkänen, E, Ellonen, P & Leppa, S 2022, ' Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma ', Blood, vol. 139, no. 12, pp. 1863-1877 . https://doi.org/10.1182/blood.2021012852
Inadequate molecular and clinical stratification of the patients with high-risk diffuse large B-cell lymphoma (DLBCL) is a clinical challenge hampering the establishment of personalized therapeutic options. We studied the translational significance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a8922736ebf9763275c471d8a04f16
https://doi.org/10.1182/blood.2021012852
https://doi.org/10.1182/blood.2021012852
Autor:
Govindasamy-Muralidharan Karthik, Mattias Rantalainen, Gustav Stålhammar, John Lövrot, Ikram Ullah, Amjad Alkodsi, Ran Ma, Lena Wedlund, Johan Lindberg, Jan Frisell, Jonas Bergh, Johan Hartman
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-11 (2017)
Abstract Background Transcriptomic profiling of breast tumors provides opportunity for subtyping and molecular-based patient stratification. In diagnostic applications the specimen profiled should be representative of the expression profile of the wh
Externí odkaz:
https://doaj.org/article/c44ea55cc846474487dfc35c4ac3061b
Autor:
Niko Välimäki, Heli Kuisma, Annukka Pasanen, Oskari Heikinheimo, Jari Sjöberg, Ralf Bützow, Nanna Sarvilinna, Hanna-Riikka Heinonen, Jaana Tolvanen, Simona Bramante, Tomas Tanskanen, Juha Auvinen, Outi Uimari, Amjad Alkodsi, Rainer Lehtonen, Eevi Kaasinen, Kimmo Palin, Lauri A Aaltonen
Publikováno v:
eLife, Vol 7 (2018)
Uterine leiomyomas (ULs) are benign tumors that are a major burden to women’s health. A genome-wide association study on 15,453 UL cases and 392,628 controls was performed, followed by replication of the genomic risk in six cohorts. Effects of the
Externí odkaz:
https://doaj.org/article/94e199383a454da09e3a65af3810b73f
Autor:
Leo Meriranta, Annika Pasanen, Riku Louhimo, Alejandra Cervera, Amjad Alkodsi, Matias Autio, Minna Taskinen, Ville Rantanen, Marja-Liisa Karjalainen-Lindsberg, Harald Holte, Jan Delabie, Rainer Lehtonen, Sampsa Hautaniemi, Sirpa Leppä
Publikováno v:
Haematologica, Vol 102, Iss 5 (2017)
Externí odkaz:
https://doaj.org/article/28cc657606594d109e90f141258ab1de
Autor:
Olli Carpén, Katja Kaipio, Kaisa Huhtinen, Antti Häkkinen, Erdogan Pekcan Erkan, Noora Andersson, Naziha Mansuri, Sampsa Hautaniemi, Anna Vähärautio, Johanna Hynninen, Tarja Lamminen, Amjad Alkodsi, Rainer Lehtonen, Kaiyang Zhang, Jun Dai, Sakari Hietanen
Publikováno v:
Bioinformatics
Motivation A major challenge in analyzing cancer patient transcriptomes is that the tumors are inherently heterogeneous and evolving. We analyzed 214 bulk RNA samples of a longitudinal, prospective ovarian cancer cohort and found that the sample comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdc90ea0a8336db5a512e998ee118f7
https://doi.org/10.1093/bioinformatics/btab178
https://doi.org/10.1093/bioinformatics/btab178