Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Alkistis Kapelouzou"'
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 7, p 1994 (2024)
Background: This study sought to assess the effect of statin therapy on myocardial inflammation in a White New Zealand rabbit model of atherogenesis. Methods: The mRNA expression levels of pro-inflammatory, pluripotency, and aging-related markers wer
Externí odkaz:
https://doaj.org/article/f318dd002de6412d8c390f4f53e245ce
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15866 (2023)
The long-term patency of vein grafts is challenged by intimal hyperplasia. We sought to explore the intricate relationships between the transcription factor Egr-1, toll-like receptors (TLRs), and stem cell genes and also assessed oligodeoxynucleotide
Externí odkaz:
https://doaj.org/article/3176886dd6694b4585110bb0cedf541e
Autor:
Antonios Halapas, Alkistis Kapelouzou, Michael Chrissoheris, Gregory Pattakos, Dennis V. Cokkinos, Konstantinos Spargias
Publikováno v:
Hellenic Journal of Cardiology, Vol 62, Iss 6, Pp 423-428 (2021)
Background: Remote ischemic preconditioning (RIPC) is being evaluated as a strategy to reduce cardiac injury and inflammation in patients undergoing diverse cardiac invasive and surgical procedures. However, it is unclear whether RIPC has protective
Externí odkaz:
https://doaj.org/article/bca2a74abcde48ceab8b14dd1638f824
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9248 (2023)
Atherosclerosis is driven by a diverse range of cellular and molecular processes. In the present study, we sought to better understand how statins mitigate proatherogenic inflammation. 48 male New Zealand rabbits were divided into eight groups, each
Externí odkaz:
https://doaj.org/article/f435579aa32741f5ba5977d56d79789c
Autor:
Alkistis Kapelouzou, Michalis Katsimpoulas, Christos Kontogiannis, Irene Lidoriki, Georgios Georgiopoulos, Christos Kourek, Christos Papageorgiou, Konstantinos S. Mylonas, Spyridon Dritsas, Alexandros Charalabopoulos, Dennis V. Cokkinos
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 2, Pp 818-830 (2021)
Background: A high-cholesterol diet (HCD) induces vascular atherosclerosis through vascular inflammatory and immunological processes via TLRs. The aim of this study is to investigate the mRNA expression of TLRs and other noxious biomarkers expressing
Externí odkaz:
https://doaj.org/article/b3ef6c88e41c4db39662eafe1138dcf4
Autor:
Alkistis Kapelouzou, Styliani Geronikolou, Irene Lidoriki, Christos Kontogiannis, Loukas Kaklamanis, Loukas Tsourelis, Dennis V. Cokkinos
Publikováno v:
Biology, Vol 12, Iss 3, p 347 (2023)
Background and Aim. Degenerative Aortic Stenosis (DAS) is a common disease that causes substantial morbidity and mortality worldwide, especially in the older population. Our aim was to further investigate novel serum and tissue biomarkers to elucidat
Externí odkaz:
https://doaj.org/article/ece42649ecd64ceabf5c020e0ae00f81
Autor:
Hatam Naase, Leanne Harling, Emaddin Kidher, Amir Sepehripour, Bao Nguyen, Alkistis Kapelouzou, Dennis Cokkinos, George Stavridis, Gianni Angelini, Paul C. Evans, Thanos Athanasiou
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 15, Iss 1, Pp 1-9 (2020)
Abstract Objectives Cardiac surgery can lead to post-operative end-organ complications secondary to activation of systemic inflammatory response. We hypothesize that surgical trauma or cardiopulmonary bypass (CPB) may initiate systemic inflammatory r
Externí odkaz:
https://doaj.org/article/2e5ca6b3ada348768ae74a590cc7d8b9
Autor:
Chrysostomos V. Aravanis, Alkistis Kapelouzou, Stylianos Vagios, Diamantis I. Tsilimigras, Michalis Katsimpoulas, Demetrios Moris, Theano D. Demesticha, Dimitrios Schizas, Alkiviadis Kostakis, Anastasios Machairas, Theodore Liakakos
Publikováno v:
Journal of Investigative Surgery, Vol 33, Iss 2, Pp 109-117 (2020)
Objective: To investigate the expression of toll-like receptors (TLRs) in the liver of septic mouse model. Materials and methods: For this study seventy-two C57BL/6J mice were utilized. Sepsis was induced by cecal ligation and puncture (CLP) in the m
Externí odkaz:
https://doaj.org/article/cf987ca5894b4a0a9d7429491aed0245
Autor:
Konstantinos S. Mylonas, Panagiotis Sarantis, Alkistis Kapelouzou, Michalis V. Karamouzis, Emmanouil I. Kapetanakis, Konstantinos Kontzoglou, Dimitrios C. Iliopoulos, Nikolaos Nikiteas, Dimitrios Schizas
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 21, p 6465 (2022)
Aims: Inflammatory dysregulation of mechanosensitive developmental genes may be central to atherogenesis. In the present seven-week model, we utilized colchicine regimens to curtail aortic atherogenesis in New Zealand White rabbits. We also explored
Externí odkaz:
https://doaj.org/article/f6e1678f2ad24baba1e69d792ce46023
Autor:
Christos Papageorgiou MD, Andreas Synetos MD, Konstantinos Tampakis MD, Hector Anninos MD, Christos Kontogiannis MD, Alkistis Kapelouzou MD, Ioannis Kanakakis MD, Dimitrios Tousoulis MD, Ioannis Paraskevaidis MD, Konstantinos Toutouzas MD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 26 (2020)
Inflammation and coagulation pathways are implicated in circulatory disease, but their interaction has not been completely deciphered yet. In this study, we investigated the association of coagulation and inflammation indices (activated clotting time
Externí odkaz:
https://doaj.org/article/6b8a98bb45394dae84da22a04f1c20d3