Comparative effects of dexmedetomidine, propofol, sevoflurane, and S-ketamine on regional cerebral glucose metabolism in humans: a positron emission tomography study

Autor: Laaksonen, L., Kallioinen, M., Långsjö, J., Laitio, T., Scheinin, A., Scheinin, J., Kaisti, K., Maksimow, A., Kallionpää, R.E., Rajala, V., Johansson, J., Kantonen, O., Nyman, M., Sirén, S., Valli, K., Revonsuo, A., Solin, O., Vahlberg, T., Alkire, M., Scheinin, H.

Publikováno v: In British Journal of Anaesthesia July 2018 121(1):281-290

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Decreased Thalamic Activity Is a Correlate for Disconnectedness during Anesthesia with Propofol, Dexmedetomidine and Sevoflurane But Not S-Ketamine.

Autor: Kantonen O; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland.; Department of Perioperative Services, Intensive Care and Pain Medicine, Satakunta Central Hospital, Pori FI-28500, Finland., Laaksonen L; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland., Alkire M; Department of Anesthesiology and Perioperative Medicine, University of California, Irvine, Irvine, California 92868., Scheinin A; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland., Långsjö J; Department of Intensive Care, Tampere University Hospital, Tampere FI-33521, Finland., Kallionpää RE; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland.; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, Turun yliopisto FI-20014, Finland., Kaisti K; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland.; Department of Anesthesiology and Intensive Care, Oulu University Hospital, Oulu FI-90029, Finland., Radek L; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland., Johansson J; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland.; Department of Radiation Sciences, Umeå University, Umeå SE-901 87, Sweden., Laitio T; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland., Maksimow A; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland., Scheinin J; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland., Nyman M; Department of Radiology, Turku University Hospital, Turku FI-20521, Finland., Scheinin M; Institute of Biomedicine and Unit of Clinical Pharmacology, University of Turku and Turku University Hospital, Turun yliopisto FI-20014, Finland., Solin O; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland., Vahlberg T; Institute of Clinical Medicine, Biostatistics, University of Turku and Turku University Hospital, Turun yliopisto FI-20014, Finland., Revonsuo A; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, Turun yliopisto FI-20014, Finland.; Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, Skövde SE-541 28, Sweden., Valli K; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland.; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, Turun yliopisto FI-20014, Finland.; Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, Skövde SE-541 28, Sweden., Scheinin H; Turku PET Centre, University of Turku and Turku University Hospital, Turku FI-20521, Finland harry.scheinin@utu.fi.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, University of Turku, Turku FI-20521, Finland.; Institute of Biomedicine and Unit of Clinical Pharmacology, University of Turku and Turku University Hospital, Turun yliopisto FI-20014, Finland.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2023 Jun 28; Vol. 43 (26), pp. 4884-4895. Date of Electronic Publication: 2023 May 24.

High-resolution within-sewer SARS-CoV-2 surveillance facilitates informed intervention.

Autor: Reeves K; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Liebig J; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Feula A; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Saldi T; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Lasda E; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Johnson W; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Lilienfeld J; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States., Maggi J; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Pulley K; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Wilkerson PJ; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Real B; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Zak G; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Davis J; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Fink M; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Gonzales P; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Hager C; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Ozeroff C; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Tat K; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Alkire M; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Butler C; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Coe E; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Darby J; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Freeman N; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Heuer H; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Jones JR; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Karr M; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Key S; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Maxwell K; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Nelson L; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Saldana E; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Shea R; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Salveson L; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Tomlinson K; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Vargas-Barriga J; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Vigil B; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States., Brisson G; University of Colorado Boulder, Medical Services, 1900 Wardenburg Drive, Boulder, CO 80309, United States., Parker R; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Leinwand LA; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States; University of Colorado Boulder, Department of Molecular, Cellular, and Developmental Biology, 1945 Colorado Avenue, Boulder, CO 80309, United States., Bjorkman K; University of Colorado Boulder, BioFrontiers Institute, 3415 Colorado Avenue, Boulder, CO 80303, United States., Mansfeldt C; University of Colorado Boulder, Department of Civil, Environmental, and Architectural Engineering, 1111 Engineering Drive, Boulder, CO 80309, United States; University of Colorado Boulder, Environmental Engineering Program, 4001 Discovery Dr, Boulder, CO 80303, United States. Electronic address: cresten.mansfeldt@colorado.edu.

Publikováno v: Water research [Water Res] 2021 Oct 01; Vol. 204, pp. 117613. Date of Electronic Publication: 2021 Aug 28.

Foundations of Human Consciousness: Imaging the Twilight Zone.

Autor: Scheinin A; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, FI-20521 Turku, Finland., Kantonen O; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland., Alkire M; University of California, Irvine, Irvine, California 92868., Långsjö J; Department of Intensive Care, Tampere University Hospital, FI-33521 Tampere, Finland., Kallionpää RE; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, FI-20521 Turku, Finland.; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, FI-20014 Turun yliopisto, Finland., Kaisti K; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland.; Department of Anesthesiology and Intensive Care, Oulu University Hospital, FI-90029 Oulu, Finland., Radek L; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland., Johansson J; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland.; Department of Radiation Sciences, Umeå University, 901 87 Umeå, Sweden., Sandman N; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, FI-20014 Turun yliopisto, Finland., Nyman M; Department of Radiology, Turku University Hospital, FI-0521 Turku, Finland., Scheinin M; Institute of Biomedicine and Unit of Clinical Pharmacology, University of Turku and Turku University Hospital, FI-20014 Turun yliopisto, Finland., Vahlberg T; Institute of Clinical Medicine, Biostatistics, University of Turku and Turku University Hospital, FI-20014 Turun yliopisto, Finland., Revonsuo A; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, FI-20014 Turun yliopisto, Finland.; Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, 541 28 Skövde, Sweden., Valli K; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, FI-20521 Turku, Finland.; Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center, University of Turku, FI-20014 Turun yliopisto, Finland.; Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, 541 28 Skövde, Sweden., Scheinin H; Turku PET Centre, University of Turku and Turku University Hospital, FI-20521 Turku, Finland harry.scheinin@utu.fi.; Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, FI-20521 Turku, Finland.; Institute of Biomedicine and Unit of Clinical Pharmacology, University of Turku and Turku University Hospital, FI-20014 Turun yliopisto, Finland.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Feb 24; Vol. 41 (8), pp. 1769-1778. Date of Electronic Publication: 2020 Dec 28.