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pro vyhledávání: '"Alkeiver S. Cannon"'
Autor:
Kontham Kulangara Varsha, Xiaoming Yang, Alkeiver S. Cannon, Yin Zhong, Mitzi Nagarkatti, Prakash Nagarkatti
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Macrophage activation syndrome (MAS) is a life-threatening complication of systemic juvenile arthritis, accompanied by cytokine storm and hemophagocytosis. In addition, COVID-19–related hyperinflammation shares clinical features of MAS. Mechanisms
Externí odkaz:
https://doaj.org/article/dee9da17dd404f94bc0e8504bbc06ec1
Autor:
Mai Fujiwara, Lucien Garo, Amrendra K. Ajay, Alkeiver S. Cannon, Panagiota Kolypetri, Shivnarayan Dhuppar, Gopal Murugaiyan
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102249- (2023)
Summary: Transforming growth factor β (TGF-β) is critical to the maintenance of intestinal immune homeostasis. Here, we present techniques for analyzing Smad molecules downstream of TGF-β receptor signaling in dextran-sulfate-sodium-induced coliti
Externí odkaz:
https://doaj.org/article/5b70cae7cd33451eb0d903bdba3370bd
Autor:
Alkeiver S. Cannon, Bryan Latrell Holloman, Kiesha Wilson, Kathryn Miranda, Nicholas Dopkins, Prakash Nagarkatti, Mitzi Nagarkatti
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The aryl hydrocarbon receptor (AhR) is a ubiquitously expressed ligand-activated transcription factor. While initially identified as an environmental sensor, this receptor has been shown more recently to regulate a variety of immune functions. AhR li
Externí odkaz:
https://doaj.org/article/a4f47f9c47bf40ca9f1db1f3da1d7662
Publikováno v:
Immunology and cell biologyREFERENCES. 101(1)
Publikováno v:
The Journal of Immunology. 208:60.06-60.06
The promiscuous aryl hydrocarbon receptor (AhR) has long been the target of immunological studies due to its expression on many immune cells. However, the specific mechanisms underlying the role of AhR activation in inflammatory disease has not been
Publikováno v:
The Journal of Immunology. 206:64.06-64.06
Upregulation of long noncoding RNA (lncRNA) AW112010 has been observed in multiple inflammatory disease models. In line with implication of this lncRNA as a regulator of inflammation, it has also been shown that AW112010 expression decreases upon tre
Autor:
Kiesha Maria Wilson, Alkeiver S Cannon, Muthanna Sultan, Prakash Nagarkatti, Mitzi Nagarkatti
Publikováno v:
The Journal of Immunology. 206:110.15-110.15
The emergence of SARS-CoV-2 variants will change the landscape of what we already know about COVID-19, making it important to understand the immunological and molecular mechanism of this illness. The virulent nature of the virus, disease outcomes and
Publikováno v:
The Journal of Immunology. 204:154.13-154.13
GTPase of the immune-associated protein 5 (Gimap5) has been implicated in immune cell maintenance and development. A mouse model comparable to autoimmune hepatitis in humans was used to study the alterations induced in the gene expression profile of