Zobrazeno 1 - 10
of 902
pro vyhledávání: '"Alkali burn"'
Autor:
Yong Li, Ya-Qiong Yang, Yong Lin, Ke Yan, Yu-Fei Lyu, Zhao-Qiang Zhang, Cai-Hong Huang, Jiao-Yue Hu, Zu-Guo Liu
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 12, Pp 2158-2166 (2024)
AIM: To establish a stable, short-time, low-cost and reliable murine model of meibomian gland dysfunction (MGD). METHODS: A filter paper sheet soaked in 1.0 mol/L sodium hydroxide (NaOH) solution was used to touch the eyelid margin of C57BL/6J mice f
Externí odkaz:
https://doaj.org/article/05cb4e9c6b4641e782b02d94d9ca79d9
Publikováno v:
Biotechnologia Acta, Vol 17, Iss 3, Pp 47-58 (2024)
Corneal injury is associated with hypoxia-induced neovascularization, which interferes optical transparency of the cornea, resulting in vision loss and blindness. The treatment of corneal damage remains a ignificant unmet medical need. Lactoferrin (L
Externí odkaz:
https://doaj.org/article/a7b24b5f9abd4d168bb8c4575b1049aa
Autor:
Hitoshi Goto, Takeshi Arima, Akira Takahashi, Yutaro Tobita, Yuji Nakano, Etsuko Toda, Akira Shimizu, Fumiki Okamoto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Alkaline burns to the cornea lead to loss of corneal transparency, which is essential for normal vision. We used a rat corneal alkaline burn model to investigate the effect of ophthalmic trimebutine solution on healing wounds caused by alkal
Externí odkaz:
https://doaj.org/article/39ac1a18cf6648be8780d85c30e3435b
Autor:
V. L. Bilous, A. O. Tykhomyrov
Publikováno v:
The Ukrainian Biochemical Journal, Vol 96, Iss 1, Pp 37-48 (2024)
Prolonged inflammation and excessive neovascularization of the cornea due to severe injury can impair optical clarity and lead to vision impairment. Plasminogen kringle (K) fragments, known as angiostatins (AS), play a well-established role as inhibi
Externí odkaz:
https://doaj.org/article/ac8aac13fad1452088611d36ce59649d
Autor:
Qian Deng, Yuelan Gao, Yujin Wang, Jiewen Mao, Yulin Yan, Zixian Yang, Yuyu Cong, Yanning Yang, Shanshan Wan
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundCorneal neovascularization (CNV) is a sight-threatening condition that necessitates epigenetic control. The role of lysine-specific demethylase 1 (LSD1) in CNV remains unclear, despite its established significance in tumor angiogenesis regu
Externí odkaz:
https://doaj.org/article/a222f0ccb87b49c3b366254c3b2e2dd6
Autor:
Neethi C. Thathapudi, Marc Groleau, Delali S. Degué, Mozhgan Aghajanzadeh Kiyaseh, Piotr Kujawa, Fouzia Soulhi, Naoufal Akla, May Griffith, Marie-Claude Robert
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Moderate corneal alkali burns such as those sustained from accidental exposure to household chemicals are treated with topical corticosteroids. Side effects include increased intraocular pressure and slowing of wound healing. Here, we c
Externí odkaz:
https://doaj.org/article/1a742e5855f14e0fab4083aa899f99b0
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Corneal neovascularization (CNV) is an important disease that causes blindness. Secretogranin III (Scg3) has emerged as a new influencing factor of neovascularization. This study analyzed the Scg3 antibody’s inhibitory effect on
Externí odkaz:
https://doaj.org/article/201f3e6cf2cc4839af51909fc1d6c895
Autor:
Mehak Vohra, Abha Gour, Jyoti Rajput, Bharti Sangwan, Monika Chauhan, Kartik Goel, Ajith Kamath, Umang Mathur, Arun Chandru, Virender Singh Sangwan, Tuhin Bhowmick, Anil Tiwari
Publikováno v:
Cells, Vol 13, Iss 5, p 379 (2024)
Purpose: Chemical eye injury is an acute emergency that can result in vision loss. Neurotrophic keratitis (NK) is the most common long-term manifestation of chemical injury. NK due to alkali burn affects ocular surface health and is one of its most c
Externí odkaz:
https://doaj.org/article/3fbeb7556f6044f1b93a03a4e60b6842
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