Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Alka Kaushal"'
Autor:
Ramesh J. L. Kandimalla, Sudesh Prabhakar, Willayat Yousuf Wani, Alka Kaushal, Nidhi Gupta, Deep Raj Sharma, V. K. Grover, Neerja Bhardwaj, Kajal Jain, Kiran Dip Gill
Publikováno v:
Biology Open, Vol 2, Iss 11, Pp 1119-1124 (2013)
Summary The two hallmarks of Alzheimer's disease (AD) are neurofibrillary tangles and amyloid plaques. Neurofibrillary tangles are formed due to the hyperphosphorylation of tau protein. There is an urgent need to develop a reliable biomarker for the
Externí odkaz:
https://doaj.org/article/f587af351d7c453f928d53b2087e9c35
Publikováno v:
Biochemical and Biophysical Research Communications. 615:43-48
Among the post-translational modifications of α-synuclein, phosphorylation has been reported to modulate the protein's nuclear localization, gene-expression and cytotoxicity. However, its effect on the functional performance of dopaminergic-neurons
Publikováno v:
Journal of Neuroscience Research. 100:681-706
Serving as a source of glutathione and up-taking and metabolizing glutamate are the primary supportive role of astrocytes for the adjacent neurons. Despite the clear physical association between astrocytes and α-synuclein, the effect of extracellula
Autor:
Rachel Couban, Varun Bhardwaj, Edward Zhou, Lehana Thabane, Alka Kaushal, Prathiba Harsha, James Paul, Mohit Bhandari, Harsha Shanthanna, Li Wang, Jason W. Busse, Erica Aranha Suzumura
Publikováno v:
British Journal of Anaesthesia. 125:779-801
Background Despite common use, the benefit of adding steroids to local anaesthetics (SLA) for chronic non-cancer pain (CNCP) injections is uncertain. We performed a systematic review and meta-analysis of English-language RCTs to assess the benefit an
Publikováno v:
The Biology of Glial Cells: Recent Advances ISBN: 9789811683121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d0a2492389fc2f8913d199d1ab939b5
https://doi.org/10.1007/978-981-16-8313-8_10
https://doi.org/10.1007/978-981-16-8313-8_10
Publikováno v:
Cells, tissues, organs. 209(4-6)
Owing to their neural crest origin, dental pulp stem cells (DPSCs) are increasingly gaining prominence in treating nervous system disease conditions. However, as per the regulatory bodies [European-Medicines Agency (EMA), Indian-Council of Medical-Re
Autor:
Fiona Campbell, Lucas Gallo, Patrick Jiho Hong, Rachel Couban, Brian Y. Hong, Alka Kaushal, Elena Kum, Li Wang, Thomas Agoritsas, Mark A. Ware, Rachelle Buchbinder, Yvgeniy Oparin, Chris J. Hong, Samantha Craigie, Mahmood AminiLari, Harsha Shanthanna, Curtis May, Yasir Rehman, Jason W. Busse, Suneel Upadhye, Ira M Price
Publikováno v:
BMJ. :n1034
Objective To determine the benefits and harms of medical cannabis and cannabinoids for chronic pain. Design Systematic review and meta-analysis. Data sources MEDLINE, EMBASE, AMED, PsycInfo, CENTRAL, CINAHL, PubMed, Web of Science, Cannabis-Med, Epis
Autor:
Willayat Yousuf Wani, P. Hemachandra Reddy, Alberto Chiarugi, Anand Ruban, Ramesh Kandimalla, Aditya Sunkaria, Jayalakshmi Vallamkondu, Deep Raj Sharma, Kiran Dip Gill, Alka Kaushal
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863:1858-1866
In the previous study, we demonstrated that dichlorvos induces oxidative stress in dopaminergic neuronal cells and subsequent caspase activation mediates apoptosis. In the present study, we evaluated the effect and mechanism of dichlorvos induced oxi
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 393(2)
Besides the effects on the striatum, the impairment of visceral organs including liver functions has been reported in Parkinson's disease (PD) patients. However, it is yet unclear if liver functions are affected in the early stage of the disease befo
Autor:
Alka Kaushal, Rachel Couban, Lehana Thabane, Jason W. Busse, Lawrence Mbuagbaw, Harsha Shanthanna
Publikováno v:
Canadian journal of anaesthesia = Journal canadien d'anesthesie. 65(11)
Pilot trials inform the design and conduct of larger scale trials. Using the Consolidated Standards of Reporting Trials (CONSORT) pilot extension guidelines, we assessed reporting quality in five high-impact anesthesia journals and explored factors a