Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Aliz Szabo"'
Autor:
Ferenc Gallyas, Fadi H. J. Ramadan, Kitti Andreidesz, Eniko Hocsak, Aliz Szabo, Antal Tapodi, Gyongyi N. Kiss, Katalin Fekete, Rita Bognar, Arpad Szanto, Zita Bognar
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1544 (2022)
Novel compounds significantly interfering with the mitochondrial energy production may have therapeutic value in triple-negative breast cancer (TNBC). This criterion is clearly fulfilled by desethylamiodarone (DEA), which is a major metabolite of ami
Externí odkaz:
https://doaj.org/article/ad4dcfba5f4646ff9eab1490fd30cdc1
Autor:
Kitti Andreidesz, Aliz Szabo, Dominika Kovacs, Balazs Koszegi, Viola Bagone Vantus, Eszter Vamos, Mostafa Isbera, Tamas Kalai, Zita Bognar, Krisztina Kovacs, Ferenc Gallyas
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 9016 (2021)
Mitochondria have emerged as a prospective target to overcome drug resistance that limits triple-negative breast cancer therapy. A novel mitochondria-targeted compound, HO-5114, demonstrated higher cytotoxicity against human breast cancer lines than
Externí odkaz:
https://doaj.org/article/ce7ba44a176e4e63bbf762d5f52e703c
Autor:
Anna Maria Cseh, Zsolt Fabian, Ruben Quintana-Cabrera, Aliz Szabo, Krisztian Eros, Maria Eugenia Soriano, Ferenc Gallyas, Luca Scorrano, Balazs Sumegi
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
PARP-1 inhibition has recently been employed in both mono- and combination therapies in various malignancies including melanoma with both promising and contradicting results reported. Although deeper understanding of the underlying molecular mechanis
Externí odkaz:
https://doaj.org/article/f381065919764ca58bfa19b4e21df72f
Autor:
Fadi H. J. Ramadan, Aliz Szabo, Dominika Kovacs, Aniko Takatsy, Rita Bognar, Ferenc Gallyas, Zita Bognar
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7346 (2020)
Previously, we showed that desethylamiodarone (DEA), a major metabolite of the widely used antiarrhythmic drug amiodarone, has direct mitochondrial effects. We hypothesized that these effects account for its observed cytotoxic properties and ability
Externí odkaz:
https://doaj.org/article/edb4022781394ab2a4154fa9e173d467
Autor:
Adam Riba, Laszlo Deres, Krisztian Eros, Aliz Szabo, Klara Magyar, Balazs Sumegi, Kalman Toth, Robert Halmosi, Eszter Szabados
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175195 (2017)
In addition to their anti-bacterial action, tetracyclines also have complex biological effects, including the modification of mitochondrial protein synthesis, metabolism and gene-expression. Long-term clinical studies have been performed using tetrac
Externí odkaz:
https://doaj.org/article/144feeb2309f4075a9aea8129f6daeca
Autor:
Katalin Sumegi, Katalin Fekete, Csenge Antus, Balazs Debreceni, Eniko Hocsak, Ferenc Gallyas, Balazs Sumegi, Aliz Szabo
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169372 (2017)
Reactive oxygen species (ROS) play a critical role in the progression of mitochondria-related diseases. A novel insulin sensitizer drug candidate, BGP-15, has been shown to have protective effects in several oxidative stress-related diseases in anima
Externí odkaz:
https://doaj.org/article/9b0cb22536ac4c51a3146f4acb3a91e6
Autor:
Robert Gabriel, Andrea Tamas, Aliz Szabo, Krisztina Kovacs, Boglarka Racz, Norbert Babai, Peter Kiss, Dora Reglodi, Krisztina Szabadfi, Laszlo Mester, Tamas Atlasz
Publikováno v:
International Journal of Molecular Sciences, Vol 11, Iss 2, Pp 544-561 (2010)
Retinal ischemia can be effectively modeled by permanent bilateral common carotid artery occlusion, which leads to chronic hypoperfusion-induced degeneration in the entire rat retina. The complex pathways leading to retinal cell death offer a complex
Externí odkaz:
https://doaj.org/article/ceee84e40b794bd8bb7e185267d71956
Autor:
Karoly Kalmar-Nagy, Peter Degrell, Aliz Szabo, Katalin Sumegi, Istvan Wittmann, Ferenc Gallyas, Balazs Sumegi
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81928 (2013)
BACKGROUND: Novel immunosuppressive therapy facilitates long term allograft survival, but acute tubular necrosis and ischemia-reperfusion during transplantation can compromise allograft function. These processes are related to oxidative stress which
Externí odkaz:
https://doaj.org/article/432bae0d2ca949e4acd5d5d8310450a6
Autor:
Eszter Bognar, Zsolt Sarszegi, Aliz Szabo, Balazs Debreceni, Nikoletta Kalman, Zsuzsanna Tucsek, Balazs Sumegi, Ferenc Gallyas
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65355 (2013)
Red wine polyphenols can prevent cardiovascular and inflammatory diseases. Resveratrol, the most extensively studied constituent, is unlikely to solely account for these beneficial effects because of its rather low abundance and bioavailability. Malv
Externí odkaz:
https://doaj.org/article/379393d63695463aadb8fecba1bad701
Autor:
Peter Kiss, Jozsef Farkas, Krisztina Kovacs, Valeria Gaal, Zsolt Biro, Aliz Szabo, Tamas Atlasz, Inez Bosnyak, Gabor Toth, Andrea Tamas, Dora Reglodi
Publikováno v:
International Journal of Peptide Research and Therapeutics. 28
Corneal epithelium responds to insults with a rapid wound healing, which is essential for maintaining vision. The proper balance of apoptotic and proliferation-stimulating pathways is critical for normal regeneration. Pituitary adenylate cyclase acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b23a8d49a49c46e64211f32719be7f81
https://doi.org/10.1007/s10989-022-10405-1
https://doi.org/10.1007/s10989-022-10405-1