Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Aliz Szabo"'
Autor:
Ferenc Gallyas, Fadi H. J. Ramadan, Kitti Andreidesz, Eniko Hocsak, Aliz Szabo, Antal Tapodi, Gyongyi N. Kiss, Katalin Fekete, Rita Bognar, Arpad Szanto, Zita Bognar
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1544 (2022)
Novel compounds significantly interfering with the mitochondrial energy production may have therapeutic value in triple-negative breast cancer (TNBC). This criterion is clearly fulfilled by desethylamiodarone (DEA), which is a major metabolite of ami
Externí odkaz:
https://doaj.org/article/ad4dcfba5f4646ff9eab1490fd30cdc1
Autor:
Kitti Andreidesz, Aliz Szabo, Dominika Kovacs, Balazs Koszegi, Viola Bagone Vantus, Eszter Vamos, Mostafa Isbera, Tamas Kalai, Zita Bognar, Krisztina Kovacs, Ferenc Gallyas
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 9016 (2021)
Mitochondria have emerged as a prospective target to overcome drug resistance that limits triple-negative breast cancer therapy. A novel mitochondria-targeted compound, HO-5114, demonstrated higher cytotoxicity against human breast cancer lines than
Externí odkaz:
https://doaj.org/article/ce7ba44a176e4e63bbf762d5f52e703c
Autor:
Anna Maria Cseh, Zsolt Fabian, Ruben Quintana-Cabrera, Aliz Szabo, Krisztian Eros, Maria Eugenia Soriano, Ferenc Gallyas, Luca Scorrano, Balazs Sumegi
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
PARP-1 inhibition has recently been employed in both mono- and combination therapies in various malignancies including melanoma with both promising and contradicting results reported. Although deeper understanding of the underlying molecular mechanis
Externí odkaz:
https://doaj.org/article/f381065919764ca58bfa19b4e21df72f
Autor:
Fadi H. J. Ramadan, Aliz Szabo, Dominika Kovacs, Aniko Takatsy, Rita Bognar, Ferenc Gallyas, Zita Bognar
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7346 (2020)
Previously, we showed that desethylamiodarone (DEA), a major metabolite of the widely used antiarrhythmic drug amiodarone, has direct mitochondrial effects. We hypothesized that these effects account for its observed cytotoxic properties and ability
Externí odkaz:
https://doaj.org/article/edb4022781394ab2a4154fa9e173d467
Autor:
Adam Riba, Laszlo Deres, Krisztian Eros, Aliz Szabo, Klara Magyar, Balazs Sumegi, Kalman Toth, Robert Halmosi, Eszter Szabados
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175195 (2017)
In addition to their anti-bacterial action, tetracyclines also have complex biological effects, including the modification of mitochondrial protein synthesis, metabolism and gene-expression. Long-term clinical studies have been performed using tetrac
Externí odkaz:
https://doaj.org/article/144feeb2309f4075a9aea8129f6daeca
Autor:
Katalin Sumegi, Katalin Fekete, Csenge Antus, Balazs Debreceni, Eniko Hocsak, Ferenc Gallyas, Balazs Sumegi, Aliz Szabo
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169372 (2017)
Reactive oxygen species (ROS) play a critical role in the progression of mitochondria-related diseases. A novel insulin sensitizer drug candidate, BGP-15, has been shown to have protective effects in several oxidative stress-related diseases in anima
Externí odkaz:
https://doaj.org/article/9b0cb22536ac4c51a3146f4acb3a91e6
Autor:
Peter Kiss, Jozsef Farkas, Krisztina Kovacs, Valeria Gaal, Zsolt Biro, Aliz Szabo, Tamas Atlasz, Inez Bosnyak, Gabor Toth, Andrea Tamas, Dora Reglodi
Publikováno v:
International Journal of Peptide Research and Therapeutics. 28
Corneal epithelium responds to insults with a rapid wound healing, which is essential for maintaining vision. The proper balance of apoptotic and proliferation-stimulating pathways is critical for normal regeneration. Pituitary adenylate cyclase acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b23a8d49a49c46e64211f32719be7f81
https://doi.org/10.1007/s10989-022-10405-1
https://doi.org/10.1007/s10989-022-10405-1
Autor:
Robert Gabriel, Andrea Tamas, Aliz Szabo, Krisztina Kovacs, Boglarka Racz, Norbert Babai, Peter Kiss, Dora Reglodi, Krisztina Szabadfi, Laszlo Mester, Tamas Atlasz
Publikováno v:
International Journal of Molecular Sciences, Vol 11, Iss 2, Pp 544-561 (2010)
Retinal ischemia can be effectively modeled by permanent bilateral common carotid artery occlusion, which leads to chronic hypoperfusion-induced degeneration in the entire rat retina. The complex pathways leading to retinal cell death offer a complex
Externí odkaz:
https://doaj.org/article/ceee84e40b794bd8bb7e185267d71956
Autor:
Ferenc Gallyas, Fadi H. J. Ramadan, Kitti Andreidesz, Eniko Hocsak, Aliz Szabo, Antal Tapodi, Gyongyi N. Kiss, Katalin Fekete, Rita Bognar, Arpad Szanto, Zita Bognar
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1544, p 1544 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1544
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1544
Novel compounds significantly interfering with the mitochondrial energy production may have therapeutic value in triple-negative breast cancer (TNBC). This criterion is clearly fulfilled by desethylamiodarone (DEA), which is a major metabolite of ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5649ba2cf3d34044b1116cc8657bd4d0
https://pubmed.ncbi.nlm.nih.gov/35163464
https://pubmed.ncbi.nlm.nih.gov/35163464
Autor:
Karoly Kalmar-Nagy, Peter Degrell, Aliz Szabo, Katalin Sumegi, Istvan Wittmann, Ferenc Gallyas, Balazs Sumegi
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81928 (2013)
BACKGROUND: Novel immunosuppressive therapy facilitates long term allograft survival, but acute tubular necrosis and ischemia-reperfusion during transplantation can compromise allograft function. These processes are related to oxidative stress which
Externí odkaz:
https://doaj.org/article/432bae0d2ca949e4acd5d5d8310450a6