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Autor:
Phillip H. Lam, Daniel J. Dooley, Cherinne Arundel, Michelle White, Bertram Pitt, Wilbert S. Aronow, Javed Butler, Prakash Deedwania, Marc R. Blackman, Gregg Fonarow, Apostolos Tsimploulis, Aliy Ahmed, Charity J. Morgan, Wen-Chih Wu, Poonam Bhyan, Deepak L. Bhatt, Ioannis Kanonidis
Publikováno v:
Journal of the American College of Cardiology. 69:911
Background: In the DIG trial, 6800 patients with HFrEF (EF≤45%) were randomized to receive either placebo (n=3403) or digoxin (n=3397) and followed for a mean of 37 months. Digoxin significantly reduced the risk of HFH by 28% (HR, 0.72; 95% CI, 0.6