Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alistair R.R. Forrest"'
Autor:
Marti Cabanes-Creus, Renina Gale Navarro, Sophia H.Y. Liao, Suzanne Scott, Rodrigo Carlessi, Ramon Roca-Pinilla, Maddison Knight, Grober Baltazar, Erhua Zhu, Matthew Jones, Elena Denisenko, Alistair R.R. Forrest, Ian E. Alexander, Janina E.E. Tirnitz-Parker, Leszek Lisowski
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 220-237 (2023)
Recent clinical successes have intensified interest in using adeno-associated virus (AAV) vectors for therapeutic gene delivery. The liver is a key clinical target, given its critical physiological functions and involvement in a wide range of genetic
Externí odkaz:
https://doaj.org/article/12d90e3f3d744253b93a5e234204995c
Autor:
Joel Kidman, Rachael M. Zemek, John-William Sidhom, Debora Correa, Nicola Principe, Fezaan Sheikh, Vanessa S. Fear, Catherine A. Forbes, Abha Chopra, Louis Boon, Ayham Zaitouny, Emma de Jong, Robert A. Holt, Matt Jones, Michael J. Millward, Timo Lassmann, Alistair R.R. Forrest, Anna K. Nowak, Mark Watson, Richard A. Lake, W. Joost Lesterhuis, Jonathan Chee
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTImmune checkpoint therapy (ICT) causes durable tumour responses in a subgroup of patients, but it is not well known how T cell receptor beta (TCRβ) repertoire dynamics contribute to the therapeutic response. Using murine models that exclude
Externí odkaz:
https://doaj.org/article/f60545e051804f9796499b61db90824e
Autor:
Xian-Yang Qin, Mitsuko Hara, Erik Arner, Yoshikuni Kawaguchi, Ikuyo Inoue, Hideki Tatsukawa, Yutaka Furutani, Keisuke Nagatsuma, Tomokazu Matsuura, Feifei Wei, Jun Kikuchi, Hideko Sone, Carsten Daub, Hideya Kawaji, Timo Lassmann, Masayoshi Itoh, Harukazu Suzuki, Piero Carninci, Yoshihide Hayashizaki, Norihiro Kokudo, Alistair R.R. Forrest, Soichi Kojima
Publikováno v:
EBioMedicine, Vol 24, Iss C, Pp 257-266 (2017)
The acute phase protein orosomucoid-1 (Orm1) is mainly expressed by hepatocytes (HPCs) under stress conditions. However, its specific function is not fully understood. Here, we report a role of Orm1 as an executer of HPC proliferation. Increases in s
Externí odkaz:
https://doaj.org/article/2d67145a46cb4efdaebcf3fdbe40b328
Autor:
Lothar C. Dieterich, Sarah Klein, Anthony Mathelier, Adriana Sliwa-Primorac, Qiaoli Ma, Young-Kwon Hong, Jay W. Shin, Michito Hamada, Marina Lizio, Masayoshi Itoh, Hideya Kawaji, Timo Lassmann, Carsten O. Daub, Erik Arner, Piero Carninci, Yoshihide Hayashizaki, Alistair R.R. Forrest, Wyeth W. Wasserman, Michael Detmar
Publikováno v:
Cell Reports, Vol 13, Iss 7, Pp 1493-1504 (2015)
VEGF-C/VEGFR-3 signaling plays a central role in lymphatic development, regulating the budding of lymphatic progenitor cells from embryonic veins and maintaining the expression of PROX1 during later developmental stages. However, how VEGFR-3 activati
Externí odkaz:
https://doaj.org/article/d61ccb55c64848fa87fa8dddc7cdee82
Autor:
Alison C. Testa, Alistair R.R. Forrest
Publikováno v:
EBioMedicine, Vol 9, Iss C, Pp 9-10 (2016)
Externí odkaz:
https://doaj.org/article/1c35d1eae5c84c7d9a4c4923feb72358
Autor:
Michiel de Hoon, Alessandro Bonetti, Charles Plessy, Yoshinari Ando, Chung-Chau Hon, Yuri Ishizu, Masayoshi Itoh, Sachi Kato, Dongyan Lin, Sho Maekawa, Mitsuyoshi Murata, Hiromi Nishiyori, Jay W. Shin, Jens Stolte, Ana Maria Suzuki, Michihira Tagami, Hazuki Takahashi, Supat Thongjuea, Alistair R.R. Forrest, Yoshihide Hayashizaki, Juha Kere, Piero Carninci
Publikováno v:
Genome Research. 32:1727-1735
In eukaryotes, capped RNAs include long transcripts such as messenger RNAs and long noncoding RNAs, as well as shorter transcripts such as spliceosomal RNAs, small nucleolar RNAs, and enhancer RNAs. Long capped transcripts can be profiled using cap a
Autor:
Takahide Nagase, Akira Saito, Patrick Micke, Yoko Yamaguchi, Daiya Takai, Alistair R.R. Forrest, Yoshihide Hayashizaki, Piero Carninci, Timo Lassmann, Hideya Kawaji, Masayoshi Itoh, Marina Lizio, Yu Mikami, Satoshi Noguchi, Hirotaka Matsuzaki, Mitsuhiro Ohshima, Bogumil Kaczkowski, Masafumi Horie
Table S1. Cell samples used for CAGE profiling. Table S2. Public datasets used in this study. Table S3. Differentially expressed promoters in FANTOM5 NSCLC cell lines. Table S4. Up-regulated/hypomethylated promoters in NSCLC cell lines. Table S5. Epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049f5d8aeb17fe16198e48f0d683c820
https://doi.org/10.1158/1541-7786.22515631.v1
https://doi.org/10.1158/1541-7786.22515631.v1
Supplementary table 2 shows Spearman correlation values between drug sensitivity and gene expression for 481 drugs studied in the CTRP dataset.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359460f5b4a10473cc79b45f983864f6
https://doi.org/10.1158/1535-7163.22510668
https://doi.org/10.1158/1535-7163.22510668
Supplementary Table 1 shows Spearman correlation values between drug sensitivity and gene expression for 250 drugs studied in the GDSC dataset.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263143ea0c0598583a70b7d33f2664ba
https://doi.org/10.1158/1535-7163.22510671
https://doi.org/10.1158/1535-7163.22510671
Supplementary Table 6a: Spearman correlation values between drug sensitivity and target expression for 86 drugs common between GDSC and CTRP. Supplementary Table 6b: Correlation matrix comparing gene expression values. There are 558 cell lines and 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b94f6841494ae3ff91861d5cd3ba67f
https://doi.org/10.1158/1535-7163.22510665
https://doi.org/10.1158/1535-7163.22510665