Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Alistair J. Barber"'
Autor:
Mi Zhou, Yuanjun Zhao, Sarah R. Weber, Christopher Gates, Nicholas J. Carruthers, Han Chen, Xiaoming Liu, Hong‐Gang Wang, Michael Ford, Matthew T. Swulius, Alistair J. Barber, Stephanie L. Grillo, Jeffrey M. Sundstrom
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 10, Pp n/a-n/a (2023)
Abstract We have shown previously that expression of R345W‐Fibulin‐3 induces epithelial‐mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells. The purpose of the current study was to determine if extracellular vesicles (EVs) de
Externí odkaz:
https://doaj.org/article/1094854df85348fabefd89bbd42510e4
Autor:
Mi Zhou, Sarah R. Weber, Yuanjun Zhao, Han Chen, Alistair J. Barber, Stephanie L. Grillo, Carson A. Wills, Hong Gang Wang, John D. Hulleman, Jeffrey M. Sundstrom
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
PurposeTo investigate the role of protein misfolding in retinal pigment epithelial (RPE) cell dysfunction, the effects of R345W-Fibulin-3 expression on RPE cell phenotype were studied.MethodsPrimary RPE cells were cultured to confluence on Transwells
Externí odkaz:
https://doaj.org/article/23db40c4680440e7ab5dafdc5ecb170f
Autor:
Salvatore L. Stella, Jasmine S. Geathers, Sarah R. Weber, Michael A. Grillo, Alistair J. Barber, Jeffrey M. Sundstrom, Stephanie L. Grillo
Publikováno v:
Cells, Vol 10, Iss 3, p 633 (2021)
Neurodegenerative retinal diseases, such as glaucoma and diabetic retinopathy, involve a gradual loss of neurons in the retina as the disease progresses. Central nervous system neurons are not able to regenerate in mammals, therefore, an often sought
Externí odkaz:
https://doaj.org/article/88f7289763834e95ab831a68341fbe44
Autor:
Allyson L. Toro, Michael D. Dennis, Joseph Giordano, Alistair J. Barber, William P. Miller, Siddharth Sunilkumar
Publikováno v:
J Biol Chem
The transcription factor nuclear factor erythroid-2-related factor 2 (Nrf2) plays a critical role in reducing oxidative stress by promoting the expression of antioxidant genes. Both individuals with diabetes and preclinical diabetes models exhibit ev
Autor:
William P. Miller, Allyson L. Toro, Siddharth Sunilkumar, Shaunaci A. Stevens, Ashley M. VanCleave, David L. Williamson, Alistair J. Barber, Michael D. Dennis
Publikováno v:
Diabetes. 71(5)
Clinical studies support a role for the protein regulated in development and DNA damage response 1 (REDD1) in ischemic retinal complications. To better understand how REDD1 contributes to retinal pathology, we examined human single-cell sequencing da
Autor:
Alistair J. Barber, Jasmine Geathers, Salvatore L Stella, Sarah R. Weber, Jeffrey M. Sundstrom, Michael Grillo, Stephanie L. Grillo
Publikováno v:
Cells, Vol 10, Iss 633, p 633 (2021)
Cells
Cells
Neurodegenerative retinal diseases, such as glaucoma and diabetic retinopathy, involve a gradual loss of neurons in the retina as the disease progresses. Central nervous system neurons are not able to regenerate in mammals, therefore, an often sought
Autor:
Mi Zhou, Matthew T. Swulius, Yuanjun Zhao, Alistair J. Barber, Sarah Weber, Jeffrey M. Sundstrom, Michael J. Ford, Stephanie Louise Grillo, Han Chen
PurposePrevious studies in our lab found that expression of R345W-Fibulin-3 induces retinal pigment epithelial (RPE) cells to undergo epithelial-mesenchymal transition (EMT). The purpose of the current study was to investigate the size, cargo and fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7746b2d817abd361634fa66d20eb4365
https://doi.org/10.1101/2020.10.05.327221
https://doi.org/10.1101/2020.10.05.327221
Autor:
Jeffrey M. Sundstrom, John D. Hulleman, Carson A. Wills, Stephanie Louise Grillo, Hong Gang Wang, Mi Zhou, Alistair J. Barber, Yuanjun Zhao, Sarah Weber, Han Chen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Purpose To investigate the role of protein misfolding in retinal pigment epithelial (RPE) cell dysfunction, the effects of R345W-Fibulin-3 expression on RPE cell phenotype were studied. Methods Primary RPE cells were cultured to confluence on Transwe
Autor:
Justin D. Etzel, Jeffrey M. Sundstrom, Stephanie L. Grillo, Yuanjun Zhao, Sarah R. Weber, Cassandra Ondeck, Alistair J. Barber, Weiwei Wang
Publikováno v:
Experimental eye research. 203
Fibulin-3 (Fib3) is a secreted glycoprotein that is expressed in the retina and has been associated with drusen formation in age-related macular degeneration (AMD). The purpose of this study was to assess whether Fib3 is associated with extracellular
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose O-GlcNAcylation of cellular proteins contributes to the pathophysiology of diabetes and evidence supports a role for augmented O-GlcNAcylation in diabetic retinopathy. The aim of this study was to investigate the impact of the renin-angiotens