Positive association of angiotensin II receptor blockers, not angiotensin-converting enzyme inhibitors, with an increased vulnerability to SARS-CoV-2 infection in patients hospitalized for suspected COVID-19 pneumonia.

Autor: Jean-Louis Georges, Floriane Gilles, Hélène Cochet, Alisson Bertrand, Marie De Tournemire, Victorien Monguillon, Maeva Pasqualini, Alix Prevot, Guillaume Roger, Joseph Saba, Joséphine Soltani, Mehrsa Koukabi-Fradelizi, Jean-Paul Beressi, Cécile Laureana, Jean-François Prost, Bernard Livarek

Publikováno v: PLoS ONE, Vol 15, Iss 12, p e0244349 (2020)

BackgroundAngiotensin-converting enzyme 2 is the receptor that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses for entry into lung cells. Because ACE-2 may be modulated by angiotensin-converting enzyme inhibitors (ACEIs) and angiote

Externí odkaz: https://doaj.org/article/4743791ebb664c89bf8d29271e9e005f

Positive association of angiotensin II receptor blockers, not angiotensin-converting enzyme inhibitors, with an increased vulnerability to SARS-CoV-2 infection in patients hospitalized for suspected COVID-19 pneumonia.

Autor: Georges, Jean-Louis¹ (AUTHOR) jgeorges@ch-versailles.fr, Gilles, Floriane¹ (AUTHOR), Cochet, Hélène¹ (AUTHOR), Bertrand, Alisson¹ (AUTHOR), De Tournemire, Marie¹ (AUTHOR), Monguillon, Victorien¹ (AUTHOR), Pasqualini, Maeva¹ (AUTHOR), Prevot, Alix¹ (AUTHOR), Roger, Guillaume¹ (AUTHOR), Saba, Joseph¹ (AUTHOR), Soltani, Joséphine¹ (AUTHOR), Koukabi-Fradelizi, Mehrsa² (AUTHOR), Beressi, Jean-Paul³ (AUTHOR), Laureana, Cécile⁴ (AUTHOR), Prost, Jean-François¹ (AUTHOR), Livarek, Bernard¹ (AUTHOR)

Publikováno v: PLoS ONE. 12/21/2020, Vol. 15 Issue 12, p1-15. 15p.