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pro vyhledávání: '"Alissa M. Rauwerdink"'
Autor:
Jennifer A. Cummings, Steven C. Almo, Brian K. Shoichet, Alissa M. Rauwerdink, Jeremiah D. Farelli, Frank M. Raushel, Sarah Barelier, Karen N. Allen, Daniel S. Hitchcock
Publikováno v:
Shoichet, Brian; Barelier, S; Cummings, JA; Rauwerdink, AM; Hitchcock, DS; Farelli, JD; et al.(2014). Substrate deconstruction and the nonadditivity of enzyme recognition. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7hs4z196
Journal of the American Chemical Society
Journal of the American Chemical Society
Predicting substrates for enzymes of unknown function is a major postgenomic challenge. Substrate discovery, like inhibitor discovery, is constrained by our ability to explore chemotypes; it would be expanded by orders of magnitude if reactive sites