Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alissa L. Severson"'
Publikováno v:
Theoretical Population Biology. 147:1-15
By providing additional opportunities for coalescence within families, the presence of consanguineous unions in a population reduces coalescence times relative to non-consanguineous populations. First-cousin consanguinity can take one of six forms di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb1b5ba5239d76da621c1d108e2e6d2
https://doi.org/10.1016/j.tpb.2022.07.002
https://doi.org/10.1016/j.tpb.2022.07.002
Publikováno v:
Theor Popul Biol
Consanguineous unions increase the frequency at which identical genomic segments are inherited along separate paths of descent, decreasing coalescence times for pairs of alleles drawn from an individual who is the offspring of a consanguineous pair.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1be28b79bd3c287f56682bcbe1d070
https://doi.org/10.1016/j.tpb.2021.03.004
https://doi.org/10.1016/j.tpb.2021.03.004
Autor:
Alissa L. Severson, Joseph Juan, Lafia Sebastian, Vy Tran, Wensheng Nie, Ian Lai, Gregory D. Wall, Monte M. Winslow, Dmitri A. Petrov, Ian P. Winters, Michael J. Rosen
Publikováno v:
Cancer Research. 83:11-11
Aberrant growth driven by genomic alterations is the defining feature of cancer, yet the temporal dynamics of this process are poorly understood. Previous efforts to model tumor growth relied on patient data or in vivo transplantation models. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9da9fe3de5ea77bf14a443e3be180d3
https://doi.org/10.1158/1538-7445.am2023-11
https://doi.org/10.1158/1538-7445.am2023-11
Autor:
Alissa L. Severson, Brian F. Byrd, Elizabeth K. Mallott, Amanda C. Owings, Michael DeGiorgio, Alida de Flamingh, Charlene Nijmeh, Monica V. Arellano, Alan Leventhal, Noah A. Rosenberg, Ripan S. Malhi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(13)
Significance California supports a high cultural and linguistic diversity of Indigenous peoples. In a partnership of researchers with the Muwekma Ohlone tribe, we studied genomes of eight present-day tribal members and 12 ancient individuals from two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2a807b675888c285dd9fa5f3becf5a
https://pubmed.ncbi.nlm.nih.gov/35312358
https://pubmed.ncbi.nlm.nih.gov/35312358
Publikováno v:
Bioinformatics
Severson, A L, Korneliussen, T S & Moltke, I 2022, ' LocalNgsRelate : a software tool for inferring IBD sharing along the genome between pairs of individuals from low-depth NGS data ', Bioinformatics, vol. 38, no. 4, pp. 1159-1161 . https://doi.org/10.1093/bioinformatics/btab732
Severson, A L, Korneliussen, T S & Moltke, I 2022, ' LocalNgsRelate : a software tool for inferring IBD sharing along the genome between pairs of individuals from low-depth NGS data ', Bioinformatics, vol. 38, no. 4, pp. 1159-1161 . https://doi.org/10.1093/bioinformatics/btab732
Motivation Inference of identity-by-descent (IBD) sharing along the genome between pairs of individuals has important uses. But all existing inference methods are based on genotypes, which is not ideal for low-depth Next Generation Sequencing (NGS) d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5365f659dc33e8618ea982ee31b991a8
Publikováno v:
Genetics
Consanguineous unions increase the rate at which identical genomic segments are paired within individuals to produce runs of homozygosity (ROH). The extent to which such unions affect identity-by-descent (IBD) genomic sharing between rather than with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cd9eb17cae94742d5e4edd7592de64
https://doi.org/10.1534/genetics.119.302136
https://doi.org/10.1534/genetics.119.302136
Autor:
Ilana M. Arbisser, Emily C. Glassberg, Lawrence H. Uricchio, Noah A. Rosenberg, Alissa L. Severson
Publikováno v:
Theor Popul Biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556831c6b413024729ebe92e1851935f
https://europepmc.org/articles/PMC6746670/
https://europepmc.org/articles/PMC6746670/
Autor:
Jonathan A. Shortt, Carlos Bustamante, Fernando L. Mendez, Genevieve L. Wojcik, Alissa L. Severson, Christopher R. Gignoux
SummaryThe assignment of Y chromosome data to related clusters, or haplogroups, is a common application in human population genetics. To enable this at scale, we developed SNAPPY. SNAPPY is a software program used to assign Y-chromosome phylogeny-inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f6894f9b6036116cbee76ed82d1a9c
https://doi.org/10.1101/454736
https://doi.org/10.1101/454736