Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Alissa C. Rothchild"'
Autor:
Dat Mai, Ana Jahn, Tara Murray, Michael Morikubo, Pamelia N. Lim, Maritza M. Cervantes, Linh K. Pham, Johannes Nemeth, Kevin Urdahl, Alan H. Diercks, Alan Aderem, Alissa C. Rothchild
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/a8b5eeaaa33d439183f3c3f68c960c42
Autor:
Alissa C. Rothchild, Britni Stowell, Girija Goyal, Cláudio Nunes-Alves, Qianting Yang, Kadamba Papavinasasundaram, Christopher M. Sassetti, Glenn Dranoff, Xinchun Chen, Jinhee Lee, Samuel M. Behar
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
ABSTRACT Mice deficient for granulocyte-macrophage colony-stimulating factor (GM-CSF−/−) are highly susceptible to infection with Mycobacterium tuberculosis, and clinical data have shown that anti-GM-CSF neutralizing antibodies can lead to increa
Externí odkaz:
https://doaj.org/article/84fda4d38ff444bc83d207a27981150e
Autor:
Dat Mai, Ana Jahn, Tara Murray, Michael Morikubo, Johannes Nemeth, Kevin Urdahl, Alan H. Diercks, Alan Aderem, Alissa C. Rothchild
As innate sentinels in the lung, alveolar macrophages (AMs) play a critical role during Mycobacterium tuberculosis (Mtb) infection as the first cells to encounter bacteria. We previously showed that AMs initially respond to Mtb infection in vivo by m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98dae982b253b4a0cc5246531b903446
https://doi.org/10.1101/2022.09.19.507309
https://doi.org/10.1101/2022.09.19.507309
Autor:
John D. Aitchison, Alan Aderem, Gregory S. Olson, Elizabeth S. Gold, Alissa C. Rothchild, Fergal J. Duffy, Johannes Nemeth, Ana N. Jahn, Alan H. Diercks
Publikováno v:
The Journal of Infectious Diseases. 225:1832-1840
Previous studies have identified whole-blood transcriptional risk and disease signatures for tuberculosis; however, several lines of evidence suggest that these signatures primarily reflect bacterial burden, which increases before symptomatic disease
Autor:
Cláudio Nunes-Alves, Matthew G Booty, Stephen M Carpenter, Alissa C Rothchild, Constance J Martin, Danielle Desjardins, Katherine Steblenko, Henrik N Kløverpris, Rajhmun Madansein, Duran Ramsuran, Alasdair Leslie, Margarida Correia-Neves, Samuel M Behar
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004849 (2015)
The immune system can recognize virtually any antigen, yet T cell responses against several pathogens, including Mycobacterium tuberculosis, are restricted to a limited number of immunodominant epitopes. The host factors that affect immunodominance a
Externí odkaz:
https://doaj.org/article/b649e79c83074039910e479c4c31f14b
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003805 (2014)
Invariant natural killer T (iNKT) cells are activated during infection, but how they limit microbial growth is unknown in most cases. We investigated how iNKT cells suppress intracellular Mycobacterium tuberculosis (Mtb) replication. When co-cultured
Externí odkaz:
https://doaj.org/article/544a7cccb9be4130a40087d33f8a9ea2
Publikováno v:
Expert Reviews in Molecular Medicine. 23
Alveolar macrophages (AMs) are lung-resident myeloid cells that sit at the interface of the airway and lung tissue. Under homeostatic conditions, their primary function is to clear debris, dead cells and excess surfactant from the airways. They also
Publikováno v:
Bio Protoc
Mycobacterium tuberculosis (Mtb) is transmitted by aerosol and can cause serious bacterial infection in the lung that can be fatal if left untreated. Mtb is now the leading cause of death worldwide by an infectious agent. Characterizing the early eve
Autor:
Jing Li, Brett Smith, Andrew T. Magis, Jongchan Choi, Leroy Hood, Sergey A. Kornilov, Guangrong Qin, Venkata R Duvvuri, Valentin Voillet, Kelsey Scherler, Christopher Lausted, Shen Dong, Jennifer Hadlock, Phil Greenberg, Nathan D. Price, D. Shane O’Mahony, Sunga Hong, Yapeng Su, Kim Murray, Yong Zhou, Naeha Subramanian, Heather A. Algren, Rick Edmark, Clifford Rostomily, Alan Aderem, Mark M. Davis, Jeffrey A. Bluestone, Dan Yuan, Jing Zhou, Alexander M. Xu, Ryan Roper, Raphael Gottardo, Cheng Dai, Christopher R. Dale, Lewis L. Lanier, Priyanka Baloni, Kai Wang, Lesley Jones, Jason D Goldman, Julie A. Wallick, Daniel Chen, Sui Huang, Sean Mackay, James R. Heath, Alissa C. Rothchild, Pamela Troisch, Zager A. Michael, Wei Wei
Publikováno v:
bioRxiv
bioRxiv, vol 1, iss 08-04
bioRxiv, vol 1, iss 08-04
Author(s): Su, Yapeng; Chen, Daniel; Lausted, Christopher; Yuan, Dan; Choi, Jongchan; Dai, Cheng; Voillet, Valentin; Scherler, Kelsey; Troisch, Pamela; Duvvuri, Venkata R; Baloni, Priyanka; Qin, Guangrong; Smith, Brett; Kornilov, Sergey; Rostomily, C