Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alissa A, Frame"'
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
The mechanisms that sense alterations in total body sodium content to facilitate sodium homeostasis in response to an acute sodium challenge that does not increase blood pressure have not been fully elucidated. We hypothesized that the renal sympathe
Externí odkaz:
https://doaj.org/article/5523167cd6444161bb615634cee3e566
Autor:
Alissa A. Frame, Richard D. Wainford
Publikováno v:
Kidney Research and Clinical Practice, Vol 36, Iss 2, Pp 117-131 (2017)
The pathophysiology of hypertension, which affects over 1 billion individuals worldwide, involves the integration of the actions of multiple organ systems, including the kidney. The kidney, which governs sodium excretion via several mechanisms includ
Externí odkaz:
https://doaj.org/article/3e14d24e16cb4cfa906f7c56fa77e694
Autor:
Tara Vanderweyde, Daniel J. Apicco, Katherine Youmans-Kidder, Peter E.A. Ash, Casey Cook, Edroaldo Lummertz da Rocha, Karen Jansen-West, Alissa A. Frame, Allison Citro, John D. Leszyk, Pavel Ivanov, Jose F. Abisambra, Martin Steffen, Hu Li, Leonard Petrucelli, Benjamin Wolozin
Publikováno v:
Cell Reports, Vol 15, Iss 7, Pp 1455-1466 (2016)
Summary: Dendritic mislocalization of microtubule associated protein tau is a hallmark of tauopathies, but the role of dendritic tau is unknown. We now report that tau interacts with the RNA-binding protein (RBP) TIA1 in brain tissue, and we present
Externí odkaz:
https://doaj.org/article/221ecb1228fa44a68f43fcab96d83b55
Autor:
Emmanouil Tampakakis, Corey E. Tabit, Monika Holbrook, Erika A. Linder, Brittany D. Berk, Alissa A. Frame, Rosa Bretón‐Romero, Jessica L. Fetterman, Noyan Gokce, Joseph A. Vita, Naomi M. Hamburg
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 1 (2016)
BackgroundEndoplasmic reticulum (ER) stress and the subsequent unfolded protein response may initially be protective, but when prolonged, have been implicated in atherogenesis in diabetic conditions. Triglycerides and free fatty acids (FFAs) are elev
Externí odkaz:
https://doaj.org/article/3f4fe872bb6d4742aa591167a6f08b6b
Autor:
Richard D Wainford, Brandi M. Wynne, William B. Farquhar, Alissa A. Frame, Alicia A. McDonough, Marie E. Latulippe
Publikováno v:
Nutr Today
This review highlights the gaps in knowledge and methodological challenges discussed during the Experimental Biology 2019 expert panel session titled "Moving the Needle on Hypertension: What Knowledge Is Needed?" Hypertension is a critical public hea
Autor:
Tara L. Moore, Alissa A. Frame, Kayla M. Nist, Parul Chaudhary, Franco Puleo, Richard D Wainford, Jesse D. Moreira, Eric Abkin, Jonique C. George
Publikováno v:
Experimental Physiology
New findings • What is the central question of this study? We hypothesized that central inflammatory processes that involve activation of microglia and astrocytes contribute to the development of Gαi2 protein-dependent, salt-sensitive hypertension
Publikováno v:
Frontiers in Physiology
The mechanisms that sense alterations in total body sodium content to facilitate sodium homeostasis in response to an acute sodium challenge that does not increase blood pressure have not been fully elucidated. We hypothesized that the renal sympathe
Autor:
Richard D Wainford, Alissa A. Frame, Jill T. Kuwabara, J. Thomas Cunningham, Casey Y. Carmichael
Publikováno v:
Experimental Physiology
NEW FINDINGS What is the central question of this study? What are the differential roles of the mechanosensitive and chemosensitive afferent renal nerves in the reno-renal reflex that promotes natriuresis, sympathoinhibition and normotension during a
Autor:
Eric Abkin, Franco Puleo, Erica Comsti, Jesse D. Moreira, Alissa A. Frame, Kiyoung Kim, Mohammed Z. Ferdaus, Richard D Wainford, Kayla M. Nist, Kathryn R Walsh, Elizabeth Faudoa
Publikováno v:
Physiol Res
Increased sympathoexcitation and renal sodium retention during high salt intake are hallmarks of the salt sensitivity of blood pressure. The mechanism(s) by which excessive sympathetic nervous system release of norepinephrine influences renal sodium
Publikováno v:
Hypertension. 74
Aim: Age-dependent hypertension (HTN) develops at different rates in men versus women. These studies tested the hypothesis that in a model of normal aging, the Sprague Dawley rat, alterations in fluid and electrolyte balance contribute to age-depende