Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alison Yueh Li"'
Autor:
Hantz E, Alison Yueh Li, Kaveh Rayani, Van Petegem F, Glen F. Tibbits, Anne M. Spuches, Steffen Lindert, Omid Haji-Ghassemi, R. J. Solaro
Cardiac troponin C (cTnC) is the calcium (Ca2+) sensing component of the troponin complex. Binding of Ca2+ to cTnC triggers a cascade of myofilament conformational changes that culminate in force production. Mutations in cTnC linked to hypertrophic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2c793a323f5ee76bba9d19d917278ac
https://doi.org/10.1101/2021.05.12.443789
https://doi.org/10.1101/2021.05.12.443789
Autor:
R. John Solaro, Alison Yueh Li, Steffen Lindert, Filip Van Petegem, Kaveh Rayani, Anne M. Spuches, Jonathan P. Davis, Glen F. Tibbits, Justin T Seffernick
Publikováno v:
The Journal of Biological Chemistry
Cardiac muscle thin filaments are composed of actin, tropomyosin, and troponin that change conformation in response to Ca2+ binding, triggering muscle contraction. Human cardiac troponin C (cTnC) is the Ca2+-sensing component of the thin filament. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f98bcd3bdeebfd40de75f4f8c2cf35
https://pubmed.ncbi.nlm.nih.gov/33548225
https://pubmed.ncbi.nlm.nih.gov/33548225
Autor:
D. Peter Tieleman, Charles M. Stevens, Ryan D. Morin, Sanam Shafaattalab, Eric Lin, Laura J. Dewar, Glen F. Tibbits, Jonathan P. Davis, Francis C. Lynn, Zachary Laksman, Filip Van Petegem, Leif Hove-Madsen, Alison Yueh Li, Shubhayan Sanatani
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Sudden unexpected death of an infant (SUDI) is a devastating occurrence for families. To investigate the genetic pathogenesis of SUDI, we sequenced >70 genes from 191 autopsy-negative SUDI victims. Ten infants sharing a previously unknown variant in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720d324560e0405da37ed8b963a3233d
https://europepmc.org/articles/PMC6452669/
https://europepmc.org/articles/PMC6452669/
Autor:
Marcel Lamothe, Alison Yueh Li, Marvin Gunawan, Jasmine Gill, Calvin Craig, Eric Lin, Bader Al-Zeer, Leif Hove-Madsen, Glen F. Tibbits, Kaveh Rayani, Sanam Shafaattalab
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The zebrafish has proven to be an excellent organism for manipulation of its genome from a long history of transcript down-regulation using morpholino oligimers to more recent genome editing tools such as CRISPR-Cas9. Early forward and reverse geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f297544fac4c05640c4f35fe9ca8456
https://doi.org/10.1016/j.margen.2019.100701
https://doi.org/10.1016/j.margen.2019.100701
Autor:
Christine E, Genge, Eric, Lin, Ling, Lee, XiaoYe, Sheng, Kaveh, Rayani, Marvin, Gunawan, Charles M, Stevens, Alison Yueh, Li, Sanam Shafaat, Talab, Thomas W, Claydon, Leif, Hove-Madsen, Glen F, Tibbits
Publikováno v:
Reviews of physiology, biochemistry and pharmacology. 171
Zebrafish (Danio rerio) are widely used as vertebrate model in developmental genetics and functional genomics as well as in cardiac structure-function studies. The zebrafish heart has been increasingly used as a model of human cardiac function, in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::115165cdaf36079866e0b69835975141
https://pubmed.ncbi.nlm.nih.gov/27538987
https://pubmed.ncbi.nlm.nih.gov/27538987
Characterization of Zebrafish Cardiac and Slow Skeletal Troponin C Paralogs by MD Simulation and ITC
Autor:
Gurpreet Singh, Cindy Li, Charles M. Stevens, Kaveh Rayani, Glen F. Tibbits, Filip Van Petegem, Bo Liang, Christine E. Genge, Janine M. Roller, Alison Yueh Li, D. Peter Tieleman
Publikováno v:
Biophysical journal. 111(1)
Zebrafish, as a model for teleost fish, have two paralogous troponin C (TnC) genes that are expressed in the heart differentially in response to temperature acclimation. Upon Ca(2+) binding, TnC changes conformation and exposes a hydrophobic patch th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a15ff33e1755b4143ca8031424f0b9e
https://pubmed.ncbi.nlm.nih.gov/27410732
https://pubmed.ncbi.nlm.nih.gov/27410732
Autor:
Ling Lee, Christine E. Genge, Marvin Gunawan, Alison Yueh Li, Glen F. Tibbits, Leif Hove-Madsen, Sanam Shafaat Talab, Thomas W. Claydon, Kaveh Rayani, Eric Lin, Xiaoye Sheng, Charles M. Stevens
Publikováno v:
Reviews of Physiology, Biochemistry and Pharmacology ISBN: 9783319438139
Zebrafish (Danio rerio) are widely used as vertebrate model in developmental genetics and functional genomics as well as in cardiac structure-function studies. The zebrafish heart has been increasingly used as a model of human cardiac function, in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f633388e69be65ea5311d3848c9af6de
https://doi.org/10.1007/112_2016_5
https://doi.org/10.1007/112_2016_5
Autor:
Bo Liang, Sanam Shafaattalab, Marvin Gunawan, Kaveh Rayani, Eric Lin, Tiffany Barszczewski, Alison Yueh Li, Jonathan P. Davis, Glen F. Tibbits
Publikováno v:
Journal of Molecular and Cellular Cardiology. 124:86
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60f4c0d9a7a0bb06d004c7665dec8d39
https://doi.org/10.1016/j.yjmcc.2018.07.018
https://doi.org/10.1016/j.yjmcc.2018.07.018
Autor:
Shafaattalab, Sanam, Alison Yueh Li, Lin, Eric, Stevens, Charles M., Dewar, Laura J., Lynn, Francis C., Sanatani, Shubhayan, Laksman, Zachary, Morin, Ryan D., van Petegem, Filip, Hove-Madsen, Leif, Peter Tieleman, D., Davis, Jonathan P., Tibbits, Glen F.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 4/2/2019, Vol. 116 Issue 14, p6969-6974, 6p
Autor:
Bo Liang, Charles M. Stevens, Alison Yueh Li, Jonathan P. Davis, Sean C. Little, Kaveh Rayani, Glen F. Tibbits
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79363 (2013)
PLoS ONE
PLoS ONE
The Ca(2+) binding properties of the FHC-associated cardiac troponin C (cTnC) mutation L29Q were examined in isolated cTnC, troponin complexes, reconstituted thin filament preparations, and skinned cardiomyocytes. While higher Ca(2+) binding affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc917a4a864d6b9e43646ac375f70bf
http://europepmc.org/articles/PMC3832503?pdf=render
http://europepmc.org/articles/PMC3832503?pdf=render