Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Alison Yeomans"'
Publikováno v:
BMJ Open, Vol 12, Iss 7 (2022)
Objectives To determine whether spontaneous reporting rates of myocarditis and pericarditis differed in immunocompromised patients compared with the whole population overall, and in terms of demographics, vaccine dose and time-to-onset.Design Systema
Externí odkaz:
https://doaj.org/article/55fa415f3d47478b9a71cf2bfb305b4d
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Objectives To combine spontaneously reported data from multiple countries to estimate reporting rate, and better understand risk factors for myocarditis and pericarditis following COVID-19 messenger RNA (mRNA) vaccines.Design Systematic review of spo
Externí odkaz:
https://doaj.org/article/9485580debb9461eba97055670a5ac66
Autor:
Andrew J. Steele, Freda K. Stevenson, Joe Taylor, Mark J. Coldwell, Graham Packham, Sarah Wilmore, Elizabeth Lemm, Alison Yeomans, Francesco Forconi, Rachel Fell, Karly-Rai Rogers-Broadway
Publikováno v:
Cellular and Molecular Life Sciences
Signaling via the B-cell receptor (BCR) is a key driver and therapeutic target in chronic lymphocytic leukemia (CLL). BCR stimulation of CLL cells induces expression of eIF4A, an initiation factor important for translation of multiple oncoproteins, a
Publikováno v:
BMJ open. 12(5)
ObjectivesTo combine spontaneously reported data from multiple countries to estimate reporting rate, and better understand risk factors for myocarditis and pericarditis following COVID-19 messenger RNA (mRNA) vaccines.DesignSystematic review of spont
Autor:
Joe Taylor, Sarah Wilmore, Sophie Marriot, Karly-Rai Rogers-Broadway, Rachel Fell, Annabel R. Minton, Tom Branch, Meg Ashton-Key, Mark Coldwell, Freda K. Stevenson, Francesco Forconi, Andrew J. Steele, Graham Packham, Alison Yeomans
Publikováno v:
Cellular signalling. 94
B-cell receptor (BCR) signaling plays a major role in the pathogenesis of B-cell malignancies and is an established target for therapy, including in chronic lymphocytic leukemia cells (CLL), the most common B-cell malignancy. We previously demonstrat
Publikováno v:
Exploration of targeted anti-tumor therapy
Exploration of Targeted Anti-tumor Therapy, Vol 1, Iss 1, Pp 3-25 (2020)
Exploration of Targeted Anti-tumor Therapy, Vol 1, Iss 1, Pp 3-25 (2020)
Cancer development is frequently associated with dysregulation of mRNA translation to enhance both increased global protein synthesis and translation of specific mRNAs encoding oncoproteins. Thus, targeted inhibition of mRNA translation is viewed as
ObjectivesTo determine whether spontaneous reporting rates of myocarditis and pericarditis differed in immunocompromised patients compared to the whole population overall, and in terms of demographics, vaccine dose, and time-to-onset.DesignSystematic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bede8a1632db6dac5bbd8ce63de76f
https://doi.org/10.1101/2021.12.20.21268102
https://doi.org/10.1101/2021.12.20.21268102
ObjectivesTo bring together spontaneously reported data from multiple countries to estimate reporting rate, and better understand risk factors for myocarditis and pericarditis following COVID-19 mRNA vaccines.DesignSystematic review of spontaneously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::160fe4bfc8a832b21cc121907e64f998
https://doi.org/10.1101/2021.09.09.21263342
https://doi.org/10.1101/2021.09.09.21263342
Autor:
Karina Close, Jun Wang, Tahrima Rahim, Sameena Iqbal, Findlay Bewicke-Copley, Andrew Clear, Martin Philpott, Annalisa D'Avola, Lola Konali, James A. Heward, Emil Kumar, Udo Oppermann, Richard Neve, Maria Calaminici, Pedro R. Cutillas, Jessica Okosun, Peter Johnson, Koorosh Korfi, John G. Gribben, Darko Barisic, Ahad F. Al Seraihi, James E. Dunford, Alison Yeomans, Ari Melnick, Shamzah Araf, Jude Fitzgibbon, Graham Packham
Publikováno v:
Blood
Loss-of-function mutations in KMT2D are a striking feature of germinal center (GC) lymphomas, resulting in decreased histone 3 lysine 4 (H3K4) methylation and altered gene expression. We hypothesized that inhibition of the KDM5 family, which demethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69f75b8e11d8e8cb74d2e87d8a74550
https://ora.ox.ac.uk/objects/uuid:7efc616c-0a6f-4725-8739-6ff679a99852
https://ora.ox.ac.uk/objects/uuid:7efc616c-0a6f-4725-8739-6ff679a99852
Autor:
Lola Koniali, Karina Close, Richard Neve, Maria Calaminici, Martin Philpott, Tahrima Rahim, Ahad F. Al Seraihi, Alison Yeomans, John G. Gribben, Findlay Bewicke-Copley, Andrew Clear, Jude Fitzgibbon, Graham Packham, James A. Heward, Jessica Okosun, Koorosh Korfi, Emil Kumar, Peter Johnson, Sameena Iqbal, Ari Melnick, Shamzah Araf, Udo Oppermann, James E. Dunford, Jun Wang, Annalisa D'Avola, Darko Barisic
Loss-of-function mutations in KMT2D are a striking feature of the germinal centre (GC) lymphomas, resulting in decreased H3K4 methylation and altered gene expression. We hypothesised that inhibition of the KDM5 family, which demethylates H3K4me3/me2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767ce07069098562f94d88c6d06275e7
https://doi.org/10.1101/2020.06.30.177477
https://doi.org/10.1101/2020.06.30.177477