Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Alison Woollard"'
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0278169 (2023)
While attempts to promote acceptance of well-evidenced science have historically focused on increasing scientific knowledge, it is now thought that for acceptance of science, trust in, rather than simply knowledge of, science is foundational. Here we
Externí odkaz:
https://doaj.org/article/491588d9d23049f38090fc626ab6cbcb
Autor:
Abigail R. R. Guillermo, Karolina Chocian, Gavriil Gavriilidis, Julien Vandamme, Anna Elisabetta Salcini, Jane Mellor, Alison Woollard
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Evidence of global heterochromatin decay and aberrant gene expression in models of physiological and premature ageing have long supported the “heterochromatin loss theory of ageing”, which proposes that ageing is aetiologicall
Externí odkaz:
https://doaj.org/article/194508ad184f48f08a8ab0577b076117
Autor:
Siyu Serena Ding, Alison Woollard
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract During development, cell division often generates two daughters with different developmental fates. Distinct daughter identities can result from the physical polarity and size asymmetry itself, as well as the subsequent activation of distinc
Externí odkaz:
https://doaj.org/article/68f41940da504c10bb9ca3f0ac8a4d02
Autor:
Dimitris Katsanos, Sneha L Koneru, Lamia Mestek Boukhibar, Nicola Gritti, Ritobrata Ghose, Peter J Appleford, Maria Doitsidou, Alison Woollard, Jeroen S van Zon, Richard J Poole, Michalis Barkoulas
Publikováno v:
PLoS Biology, Vol 15, Iss 11, p e2002429 (2017)
Biological systems are subject to inherent stochasticity. Nevertheless, development is remarkably robust, ensuring the consistency of key phenotypic traits such as correct cell numbers in a certain tissue. It is currently unclear which genes modulate
Externí odkaz:
https://doaj.org/article/6277508cb47d427395d2628aabc8f068
Autor:
Emily A. Baker, Alison Woollard
Publikováno v:
Journal of Developmental Biology, Vol 7, Iss 4, p 19 (2019)
Comparative developmental biology and comparative genomics are the cornerstones of evolutionary developmental biology. Decades of fruitful research using nematodes have produced detailed accounts of the developmental and genomic variation in the nema
Externí odkaz:
https://doaj.org/article/f8600dfd2c644b5990092aa498befa11
Publikováno v:
Biology Open, Vol 2, Iss 7, Pp 718-727 (2013)
Summary Caenorhabditis elegans seam cells divide in the stem-like mode throughout larval development, with the ability to both self-renew and produce daughters that differentiate. Seam cells typically divide asymmetrically, giving rise to an anterior
Externí odkaz:
https://doaj.org/article/447a5c61547f49dab2b10132eb094eff
Autor:
Simone Prömel, Marie Frickenhaus, Samantha Hughes, Lamia Mestek, David Staunton, Alison Woollard, Ioannis Vakonakis, Torsten Schöneberg, Ralf Schnabel, Andreas P. Russ, Tobias Langenhan
Publikováno v:
Cell Reports, Vol 2, Iss 2, Pp 321-331 (2012)
Adhesion class G protein-coupled receptors (aGPCR) form the second largest group of seven-transmembrane-spanning (7TM) receptors whose molecular layout and function differ from canonical 7TM receptors. Despite their essential roles in immunity, tumor
Externí odkaz:
https://doaj.org/article/d46d010d9fbc404a8102cca8d868f516
Autor:
Alison Woollard
Publikováno v:
eLife, Vol 3 (2014)
Following a year of public engagement activities associated with the Royal Institution Christmas Lectures, Alison Woollard explains why scientists need to communicate with the public.
Externí odkaz:
https://doaj.org/article/b19a614008c0428fbd8a70c49513123f
Autor:
Melissa LaBonty, Cleo Szmygiel, Lauren E Byrnes, Samantha Hughes, Alison Woollard, Erin J Cram
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101945 (2014)
Wnt signaling is tightly regulated during animal development and controls cell proliferation and differentiation. In C. elegans, activation of Wnt signaling alters the activity of the TCF/LEF transcription factor, POP-1, through activation of the Wnt
Externí odkaz:
https://doaj.org/article/05e4623340504059a5ef150e7d7232b4
Autor:
Samantha Hughes, Henry Wilkinson, Sophie P R Gilbert, Marcia Kishida, Siyu Serena Ding, Alison Woollard
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114998 (2014)
Correct cell fate choice is crucial in development. In post-embryonic development of the hermaphroditic Caenorhabitis elegans, distinct cell fates must be adopted in two diverse tissues. In the germline, stem cells adopt one of three possible fates:
Externí odkaz:
https://doaj.org/article/045c3e4564ac43818dc7017f860cf662