Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alison Tedcastle"'
Autor:
Alison Tedcastle, Thomas Wilton, Elaine Pegg, Dimitra Klapsa, Erika Bujaki, Ryan Mate, Martin Fritzsche, Manasi Majumdar, Javier Martin
Publikováno v:
Viruses, Vol 14, Iss 1, p 143 (2022)
Infection with enterovirus D68 (EV-D68) has been linked with severe neurological disease such as acute flaccid myelitis (AFM) in recent years. However, active surveillance for EV-D68 is lacking, which makes full assessment of this association difficu
Externí odkaz:
https://doaj.org/article/ad1bfe828ebb4e00af16ee57e9c5999b
Autor:
Arthur Dyer, Ying Di, Hugo Calderon, Sam Illingworth, Gray Kueberuwa, Alison Tedcastle, Phil Jakeman, Suet Lin Chia, Alice Brown, Michael A. Silva, David Barlow, John Beadle, Terry Hermiston, David J.P. Ferguson, Brian Champion, Kerry D. Fisher, Leonard W. Seymour
Publikováno v:
Molecular Therapy: Oncolytics, Vol 4, Iss C, Pp 18-30 (2017)
Enadenotucirev (EnAd) is a chimeric group B adenovirus isolated by bioselection from a library of adenovirus serotypes. It replicates selectively in and kills a diverse range of carcinoma cells, shows effective anticancer activity in preclinical syst
Externí odkaz:
https://doaj.org/article/002ab69ebda84c369b82dc56d1ee6d03
Autor:
Pei Liu, Yadi Yuan, Bopei Cui, Yaqian Huo, Lianlian Bian, Lei Chen, Siyuan Liu, Chenfei Wang, Yingzhi Xu, Alison Tedcastle, Fan Gao, Qunying Mao, Javier Martin, Zhenglun Liang
Publikováno v:
Viruses, Vol 13, Iss 5, p 720 (2021)
Enterovirus A-71 (EV71) is a global, highly contagkkious pathogen responsible for severe cases of hand-food-mouth-disease (HFMD). The use of vaccines eliciting cross neutralizing antibodies (NTAbs) against the different circulating EV71 sub-genotypes
Externí odkaz:
https://doaj.org/article/16c32e7b2146475ca70c0c5389684126
Autor:
Dimitra Klapsa, Thomas Wilton, Andrew Zealand, Erika Bujaki, Eugene Saxentoff, Catherine Troman, Alexander G Shaw, Alison Tedcastle, Manasi Majumdar, Ryan Mate, Joyce O Akello, Shahin Huseynov, Ali Zeb, Maria Zambon, Anita Bell, José Hagan, Matthew J Wade, Mary Ramsay, Nicholas C Grassly, Vanessa Saliba, Javier Martin
Publikováno v:
Lancet
BACKGROUND: The international spread of poliovirus exposes all countries to the risk of outbreaks and is designated a Public Health Emergency of International Concern by WHO. This risk can be exacerbated in countries using inactivated polio vaccine,
Autor:
Natalie J Kingston, Joseph S Snowden, Agnieszka Martyna, Mona Shegdar, Keith Grehan, Alison Tedcastle, Elaine Pegg, Helen Fox, Andrew J Macadam, Javier Martin, James M Hogle, David J Rowlands, Nicola J Stonehouse
Enterovirus A71 (EVA71) causes widespread disease in young children with occasional fatal consequences. In common with other picornaviruses, both empty capsids (ECs) and infectious virions are produced during the viral lifecycle. While initially anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6b0829e1b634e1f8b5dad2afac80f5
https://doi.org/10.1101/2023.01.30.526315
https://doi.org/10.1101/2023.01.30.526315
Autor:
Javier Martin, Yaqian Huo, Qunying Mao, Fan Gao, Yingzhi Xu, Alison Tedcastle, Bopei Cui, Siyuan Liu, Chenfei Wang, Zhenglun Liang, Pei Liu, Lianlian Bian, Lei Chen, Yadi Yuan
Publikováno v:
Viruses
Volume 13
Issue 5
Viruses, Vol 13, Iss 720, p 720 (2021)
Volume 13
Issue 5
Viruses, Vol 13, Iss 720, p 720 (2021)
Enterovirus A-71 (EV71) is a global, highly contagkkious pathogen responsible for severe cases of hand-food-mouth-disease (HFMD). The use of vaccines eliciting cross neutralizing antibodies (NTAbs) against the different circulating EV71 sub-genotypes
Autor:
Laura Crawt, Peter Rigsby, Philip D. Minor, Javier Martin, Gillian Cooper, Alison Tedcastle, Eleanor Atkinson, Elaine Pegg
Publikováno v:
The Journal of infectious diseases. 221(4)
BACKGROUND Following the declaration of wild-type 2 poliovirus eradication in 2015, the type 2 component was removed from the live-attenuated oral polio vaccine (OPV). This change implies a need to improve global coverage through routine immunization
Publikováno v:
Molecular Therapy. 24(4):796-804
Spread of oncolytic viruses through tumor tissue is essential to effective virotherapy. Interstitial matrix is thought to be a significant barrier to virus particle convection between "islands" of tumor cells. One way to address this is to encode mat
Publikováno v:
Human Gene Therapy. 26:249-256
Developing effective anticancer treatments is a particular challenge, as agents must contend with not only the target cellular biology, but also with the complex tumor microenvironment. Here we discuss various in vitro strategies that have sought to
Publikováno v:
Human Gene Therapy Methods. 25:154-165
Wild-type Sindbis virus (SV) shows promise as an oncolytic agent, although potential off-target replication is a safety concern. To remove possible pathology reflecting virus replication in liver, muscle, and/or hematopoietic cells, microRNA (miR)-re