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pro vyhledávání: '"Alison Sandoval"'
Autor:
Ian B. Moses, Rick Rodriguez, Peter Robert Rose, Corey L. Stanchina, Cuthbertson Timothy J, Asayuki Kamatani, Pieter D. de Koning, Alison Sandoval, Kyle Kissick, Robert Moore, Leera Rahman, Douglas McAndrew, Armando Urbina, David C. Boyles
Publikováno v:
Organic Process Research & Development. 15:1018-1026
A robust six-step process for the synthesis of crizotinib, a novel c-Met/ALK inhibitor currently in phase III clinical trials, has been developed and used to deliver over 100 kg of API. The process includes a Mitsunobu reaction, a chemoselective redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fd5a1469f77db90ff994ded3cb5273e
https://doi.org/10.1021/op200131n
https://doi.org/10.1021/op200131n
